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1. (WO1995024908) USE OF NITRIC OXIDE-RELEASING POLYMERS TO TREAT RESTENOSIS AND RELATED DISORDERS
국제사무국에 기록된 최신 서지정보   

공개번호: WO/1995/024908 국제출원번호: PCT/US1995/003040
공개일: 21.09.1995 국제출원일: 09.03.1995
국제예비심사 청구일: 29.09.1995
IPC:
A61K 31/785 (2006.01)
A SECTION A — 생활필수품 농업
61
위생학; 의학 또는 수의학
K
의약용, 치과용 또는 화장용 제제
31
유기 활성 성분을 함유 하는 의약품 제재
74
합성 중합체
785
질소를 함유하는 중합체
출원인:
THE UNITED STATES OF AMERICA, represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES [US/US]; National Institutes of Health Office of Technology Transfer Box OTT Bethesda, MD 20892-9902, US
COMEDICUS, INC. [US/US]; 3050 Jamestown Road Long Lake, MN 55356, US
발명자:
KEEFER, Larry, K.; US
HUTSELL, Thomas, C.; US
대리인:
GAGALA, Bruce, M. ; Leydig, Voit & Mayer, Ltd. Suite 4900 Two Prudential Plaza Chicago, IL 60601-6780, US
우선권 정보:
214,37217.03.1994US
발명의 명칭: (EN) USE OF NITRIC OXIDE-RELEASING POLYMERS TO TREAT RESTENOSIS AND RELATED DISORDERS
(FR) UTILISATION DE POLYMERES LIBERANT DE L'ACIDE NITRIQUE DANS LE BUT DE TRAITER LA RESTENOSE ET DES MALADIES APPARENTEES
요약서:
(EN) Methods of amelioration, treatment and prevention for restenosis and related disorders are provided. Methods involve the administration of nitric oxide by a nitric oxide delivery means comprising a restenosis-ameliorating or therapeutically/prophylactically effective amount of a polymer to which is bound a nitric oxide-releasing N2O2- functional group or a compound comprising a nitric oxide-releasing N2O2- functional group. Also provided are nitric oxide delivery means comprising such nitric oxide-releasing polymers or compounds for use in such methods. Preferably, the delivery means is coated with a nitric oxide-releasing polymer, which may be biodegradable, and enables the controllable and predictable release of NO to a given site in such a manner that effective ameliorating, prophylactic or therapeutic dosing is realized.
(FR) L'invention concerne des procédés d'amélioration, de traitement et de prévention de la resténose et de maladies apparentées. Ces procédés consistent à administrer de l'oxyde nitrique par l'intermédiaire d'un moyen d'administration d'oxyde nitrique comprenant une quantité améliorant la resténose ou thérapeutiquement/prophylactiquement efficace d'un polymère auquel est fixé un groupe fonctionnel/de N2O2- libérant de l'oxyde nitrique ou un composé comprenant un groupe fonctionnel de N2O2- libérant de l'oxyde nitrique. Elle concerne également des moyens d'administration d'oxyde nitrique comprenant lesdits polymères ou lesdits composés de libération d'oxyde nitrique. De préférence, le moyen d'administration est revêtu par un polymère libérant de l'oxyde nitrique, qui peut être biodégradable et permet d'effectuer la libération contrôlée et prévisible de NO à un site donné, de façon à réaliser une amélioration efficace, ainsi qu'un dosage prophylactique ou thérapeutique.
지정국: AM, AT, AU, BB, BG, BR, BY, CA, CH, CN, CZ, DE, DK, EE, ES, FI, GB, GE, HU, JP, KE, KG, KP, KR, KZ, LK, LR, LT, LU, LV, MD, MG, MN, MW, MX, NL, NO, NZ, PL, PT, RO, RU, SD, SE, SI, SK, TJ, TT, UA, UZ, VN
아프리카지역 지식재산권기구(ARIPO) (KE, MW, SD, SZ, UG)
유럽 특허청(EPO) (AT, BE, CH, DE, DK, ES, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, ML, MR, NE, SN, TD, TG)
공개언어: 영어 (EN)
출원언어: 영어 (EN)