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4. (WO2013169361) IRON CHELATORS AS HIV-1 INHIBITORS
국제사무국에 기록된 최신 서지정보   

공개번호:    WO/2013/169361    국제출원번호:    PCT/US2013/031231
공개일: 14.11.2013 국제출원일: 14.03.2013
IPC:
C07C 337/00 (2006.01), C07C 337/08 (2006.01), A61P 35/00 (2006.01)
출원인: HOWARD UNIVERSITY [US/US]; 2400 Sixth Street N.W. Washington, DC 20059 (US)
발명자: NEKHAI, Sergei; (US).
KOVALSKYY, Dmytro Borisovych; (US)
대리인: KRATZ, Rudy; Fitch, Even, Tabin & Flannery 120 S. Lasalle Street Suite 1600 Chicago, IL 60603 (US)
우선권 정보:
61/644,842 09.05.2012 US
발명의 명칭: (EN) IRON CHELATORS AS HIV-1 INHIBITORS
(FR) CHÉLATEURS DU FER EN TANT QU'INHIBITEURS DU VIH-1
요약서: front page image
(EN)The present invention relates to chelator compounds for chelating metal ions. In particular, the present invention relates to (thio)semicarbazone compounds and (thio)hydrazone compounds, such as PpYeT and PpYaT, which are chelators for metal ions, including iron ions. Therapeutic use of such compounds and/ or their metal ion complexes, includes methods for treating and inhibiting HIV-1 replication, particularly in HIV-1 infected cells.
(FR)La présente invention concerne des composés chélateurs destinés à chélater des ions métalliques. En particulier, la présente invention concerne des composés de (thio)semicarbazone et des composés de (thio)hydrazone, tels que PpYeT et PpYaT, qui sont des chélateurs d'ions métalliques, y compris les ions de fer. L'utilisation thérapeutique de tels composés et/ou de leurs complexes d'ions métalliques, comprend des procédés de traitement et d'inhibition de la réplication du VIH-1, en particulier dans des cellules infectées par le VIH-1.
지정국: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
공개언어: English (EN)
출원언어: English (EN)