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1. (WO2017107945) CRYSTALLINE FORM OF BENZOATE OF DIPEPTIDYL PEPTIDASE-IV INHIBITOR
국제사무국에 기록된 최신 서지정보    정보 제출

공개번호:    WO/2017/107945    국제출원번호:    PCT/CN2016/111445
공개일: 29.06.2017 국제출원일: 22.12.2016
IPC:
C07D 471/04 (2006.01), A61K 31/4545 (2006.01), A61P 3/10 (2006.01), A61P 5/50 (2006.01), A61P 3/06 (2006.01)
출원인: XUANZHU PHARMA CO.,LTD. [CN/CN]; 2518, Tianchen Street, National High-tech Development Zone Jinan, Shandong 250101 (CN)
발명자: SHU, Chutian; (CN).
WANG, Zhenhua; (CN)
대리인: CCPIT PATENT AND TRADEMARK LAW OFFICE; 8th Floor, Vantone New World Plaza, 2 Fuchengmenwai Street, Xicheng District Beijing 100037 (CN)
우선권 정보:
201510990347.X 24.12.2015 CN
발명의 명칭: (EN) CRYSTALLINE FORM OF BENZOATE OF DIPEPTIDYL PEPTIDASE-IV INHIBITOR
(FR) FORME CRISTALLINE DE BENZOATE D'INHIBITEUR DE DIPEPTIDYL PEPTIDASE-IV
(ZH) 二肽基肽酶-IV抑制剂的苯甲酸盐的晶型
요약서: front page image
(EN)The present invention relates to a crystalline form of benzoate of a dipeptidyl peptidase-IV inhibitor, a method for preparing the same, a pharmaceutical composition, and a use thereof. Specifically, the present invention relates to a crystalline form of benzoate of a compound used as a dipeptidyl peptidase-IV inhibitor and represented by formula (1), namely (R)-2-((7-(3-aminopiperidine-1-yl)-3,5-dimethyl-2-oxo-2,3-dihydro-1H-imidazo(4,5-b)pyridine-1-yl)methyl)benzonitrile, a method for preparing the same, a pharmaceutical composition, and a use thereof.
(FR)La présente invention concerne une forme cristalline de benzoate d'un inhibiteur de dipeptidyl-peptidase-IV, son procédé de préparation, une composition pharmaceutique, et une utilisation associée. Plus précisément, la présente invention concerne une forme cristalline de benzoate d'un composé utilisé comme inhibiteur de dipeptidyl peptidase-IV et représenté par la formule (1), à savoir le (R)-2-((7-(3-aminopipéridin-1-yl)-3,5-diméthyl-2-oxo-2,3-dihydro-1H-imidazo(4,5-b)pyridin-1-yl)méthyl)benzonitrile, son procédé de préparation, une composition pharmaceutique et une utilisation associée.
(ZH)本发明涉及二肽基肽酶-IV抑制剂的苯甲酸盐的晶型、其制备方法、药物组合物及应用。具体地涉及作为二肽基肽酶-IV抑制剂的式(1)所示化合物(R)-2-((7-(3-氨基哌啶-1-基)-3,5-二甲基-2-氧代-2,3-二氢-1H-咪唑并(4,5-b)吡啶-1-基)甲基)苯甲腈的苯甲酸盐的晶型、其制备方法、药物组合物和应用。
지정국: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
공개언어: Chinese (ZH)
출원언어: Chinese (ZH)