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1. (WO2002044727) METHOD OF MEASURING BINDING ACTIVITY OF LIGAND-BINDING PROTEIN HAVING POOR CHEMICAL STABILITY TO FIRST LIGAND
국제사무국에 기록된 최신 서지정보   

공개번호:    WO/2002/044727    국제출원번호:    PCT/JP2001/010494
공개일: 06.06.2002 국제출원일: 30.11.2001
국제예비심사 청구일:    30.11.2001    
IPC:
G01N 33/543 (2006.01), G01N 33/557 (2006.01), G01N 33/68 (2006.01)
출원인: CHUGAI SEIYAKU KABUSHIKI KAISHA [JP/JP]; 5-1, Ukima 5-chome Kita-ku, Tokyo 115-8543 (JP) (For All Designated States Except US).
KAKUTA, Masaya [JP/JP]; (JP) (For US Only).
TSUCHIYA, Mikako [JP/JP]; (JP) (For US Only)
발명자: KAKUTA, Masaya; (JP).
TSUCHIYA, Mikako; (JP)
대리인: SHAMOTO, Ichio; Yuasa and Hara Section 206, New Ohtemachi Bldg. 2-1, Ohtemachi 2-chome Chiyoda-ku, Tokyo 100-0004 (JP)
우선권 정보:
2000-364593 30.11.2000 JP
발명의 명칭: (EN) METHOD OF MEASURING BINDING ACTIVITY OF LIGAND-BINDING PROTEIN HAVING POOR CHEMICAL STABILITY TO FIRST LIGAND
(FR) PROCEDE DE MESURE DE L'ACTIVITE DE LIAISON D'UNE PROTEINE SE LIANT A UN LIGAND PRESENTANT UNE FAIBLE STABILITE CHIMIQUE A UN PREMIER LIGAND
요약서: front page image
(EN)A method of measuring the binding activity of a ligand-binding protein which has a poor chemical stability to a first ligand characterized by comprising fixing a second ligand capable of binding to the above-described ligand-binding protein at a binding site other than the binding site of the ligand-binding protein to the first protein, allowing the protein to bind to the second ligand, and then measuring the binding activity of the protein to the first ligand by the surface plasmon resonance.
(FR)L'invention concerne un procédé de mesure de l'activité de liaison d'une protéine se liant à un ligand présentant une faible stabilité chimique à un premier ligand. Ce procédé est caractérisé en ce qu'il consiste à fixer un second ligand capable de se lier à la protéine se liant à un ligand susmentionnée, au niveau d'un site de liaison autre que le site de liaison de la protéine se liant à un ligand, à la première protéine, à permettre à la protéine de se lier au second ligand et puis à mesurer l'activité de liaison de la protéine au premier ligand au moyen de la résonance plasmon de surface.
지정국: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
공개언어: Japanese (JA)
출원언어: Japanese (JA)