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1. CN108291889 - AN OUTER LAYER FOR ENZYME SENSORS

官庁
中華人民共和国
出願番号 201680068219.2
出願日 23.11.2016
公開番号 108291889
公開日 17.07.2018
特許番号 108291889
特許付与日 12.03.2021
公報種別 B
IPC
G01N 27/327
G物理学
01測定;試験
N材料の化学的または物理的性質の決定による材料の調査または分析
27電気的,電気化学的,または磁気的手段の利用による材料の調査または分析
26電気化学的変量の調査によるもの;電解または電気泳動の利用によるもの
28電解セル要素
30電極,例.試験電極;半電池
327生化学的電極
C12Q 1/00
C化学;冶金
12生化学;ビール;酒精;ぶどう酒;酢;微生物学;酵素学;突然変異または遺伝子工学
Q酵素,核酸または微生物を含む測定または試験方法;そのための組成物または試験紙;その組成物を調製する方法;微生物学的または酵素学的方法における状態応答制御
1酵素,核酸または微生物を含む測定または試験方法;そのための組成物;そのような組成物の製造方法
CPC
C12Q 1/002
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
001Enzyme electrodes
002Electrode membranes
G01N 27/3271
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
26by investigating electrochemical variables; by using electrolysis or electrophoresis
28Electrolytic cell components
30Electrodes, e.g. test electrodes; Half-cells
327Biochemical electrodes ; , e.g. electrical or mechanical details for in vitro measurements
3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
C08L 33/12
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
33Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
04Homopolymers or copolymers of esters
06of esters containing only carbon, hydrogen and oxygen, which oxygen atoms are present only as part of the carboxyl radical
10Homopolymers or copolymers of methacrylic acid esters
12Homopolymers or copolymers of methyl methacrylate
C08L 2203/20
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
2203Applications
20use in electrical or conductive gadgets
C08L 2205/03
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
2205Polymer mixtures characterised by other features
03containing three or more polymers in a blend
C08L 2207/02
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
2207Properties characterising the ingredient of the composition
02Heterophasic composition
出願人 RADIOMETER MEDICAL APS
雷迪奥米特医学公司
発明者 KJAER THOMAS
T.克亚尔
HANSEN THOMAS STEEN
T.S.汉森
CLAUSEN LYDIA DAHL
L.D.克劳森
代理人 北京市柳沈律师事务所 11105
北京市柳沈律师事务所 11105
優先権情報 PA201500755 27.11.2015 DK
発明の名称
(EN) AN OUTER LAYER FOR ENZYME SENSORS
(ZH) 用于酶传感器的外层
要約
(EN)
The present application discloses a planar enzyme sensor for measuring the concentration of an analyte in a solution comprising a substrate of an electrically insulating material supporting an electrode layer of an electrically conductive material. The substrate and electrode layer have a plurality of layers disposed thereon which include an enzyme layer and a microporous outer layer covering theenzyme layer, wherein the outer layer comprises a continuous phase of a water-resistant polymer (e.g. a polyvinyl acetate or an acrylate copolymer), a protein (e.g. an enzyme) embedded in the continuous phase, and possibly polytetrafluoroethylene particles. The enzyme and the polytetrafluoroethylene particles provide a controlled porosity to the outer membrane.

(ZH)
本申请公开了一种用于测量溶液中分析物的浓度的平面酶传感器,所述传感器包括支撑导电材料的电极层的电绝缘材料的基板。所述基板和电极层具有设置在其上的多个层,所述多个层包括酶层和覆盖所述酶层的微孔外层,其中所述外层包含防水性聚合物(例如,聚乙酸乙烯酯或丙烯酸酯共聚物)的连续相、嵌入所述连续相中的蛋白质(例如,酶),以及可能的聚四氟乙烯颗粒。所述酶和所述聚四氟乙烯颗粒向所述外膜提供受控的孔隙度。