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1. (WO2018202202) COMPOUND WITH KINASE INHIBITORY ACTIVITY AND PREPARATION METHOD AND USE THEREOF

Pub. No.:    WO/2018/202202    International Application No.:    PCT/CN2018/085848
Publication Date: Fri Nov 09 00:59:59 CET 2018 International Filing Date: Tue May 08 01:59:59 CEST 2018
IPC: C07D 401/14
C07D 403/14
C07D 405/14
A61K 31/506
A61K 31/5377
A61K 31/501
A61P 35/00
Applicants: SELECTION BIOSCIENCE LLC
上海时莱生物技术有限公司
Inventors: ZHANG, Fuyao
张富尧
CHEN, Xianjie
陈先杰
FANG, Weijun
方为军
SUN, Hua
孙华
Title: COMPOUND WITH KINASE INHIBITORY ACTIVITY AND PREPARATION METHOD AND USE THEREOF
Abstract:
The present invention provides a compound as shown in general formulas (I) or (II) and a pharmaceutically acceptable salt, an isomer or a mixture form thereof, a solvate, a polymorph, a stable isotope derivative, or a prodrug of the same. The compound of the present invention has CDK kinase inhibitory activity and can be used in treating a disease related to CDK kinase, such as a cancer.