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1. WO2008022994 - USE OF AZABICYCLO HEXANE DERIVATIVES

公開番号 WO/2008/022994
公開日 28.02.2008
国際出願番号 PCT/EP2007/058636
国際出願日 20.08.2007
IPC
A61K 31/403 2006.01
A生活必需品
61医学または獣医学;衛生学
K医薬用,歯科用又は化粧用製剤
31有機活性成分を含有する医薬品製剤
33複素環式化合物
395環異種原子として窒素を持つもの,例.グアネチジン,リファマイシン
40環異種原子として1個の窒素をもつ5員環を有するもの,例.スルピリド,スクシンイミド,トルメチン,プフロメシル
403炭素環と縮合したもの,例.カルバゾール
CPC
A61P 1/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
04for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
A61P 1/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
08for nausea, cinetosis or vertigo; Antiemetics
A61P 15/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders
10for impotence
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 25/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
08Antiepileptics; Anticonvulsants
A61P 25/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
14for treating abnormal movements, e.g. chorea, dyskinesia
出願人
  • GLAXO GROUP LIMITED [GB]/[GB] (AllExceptUS)
  • ANDERTON, Clare Louise [GB]/[GB] (UsOnly)
  • BACCHI, Sergio [IT]/[IT] (UsOnly)
  • BEATO, Stefania [IT]/[IT] (UsOnly)
  • SARTOR, Franco [IT]/[IT] (UsOnly)
発明者
  • ANDERTON, Clare Louise
  • BACCHI, Sergio
  • BEATO, Stefania
  • SARTOR, Franco
代理人
  • DOLTON, Peter, I
優先権情報
0616574.021.08.2006GB
PCT/EP2006/00831421.08.2006EP
公開言語 (言語コード) 英語 (EN)
出願言語 (言語コード) 英語 (EN)
指定国 (国コード)
発明の名称
(EN) USE OF AZABICYCLO HEXANE DERIVATIVES
(FR) UTILISATION DE DÉRIVÉS DE L'AZABICYCLO HEXANE
要約
(EN)
The present invention relates to the tartrate salt of 1-[2-fluoro-4-(trifluoromethyl)phenyl]-3-(3-{[4-methyl-5-(4-methyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]thio}propyl)-3-azabicyclo[3.1.0]-hexane and solvates thereof, pharmaceutical formulations, processes for their preparation, and their use in medicine.
(FR)
La présente invention concerne un sel, le tartrate de 1-[2-fluoro-4-(trifluorométhyl)phényl]-3-(3-{[4-méthyl-5-(4-méthyl-1,3-oxazol-5-yl)-4H-1,2,4-triazol-3-yl]thio}propyl)-3-azabicyclo[3.1.0]-hexane, et ses solvates, des formulations pharmaceutiques, leurs procédés de préparation et leur utilisation en médecine.
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