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1. WO2007102562 - 新規抗血栓薬

公開番号 WO/2007/102562
公開日 13.09.2007
国際出願番号 PCT/JP2007/054489
国際出願日 01.03.2007
IPC
A61K 38/00 2006.01
A生活必需品
61医学または獣医学;衛生学
K医薬用,歯科用又は化粧用製剤
38ペプチドを含有する医療製剤
A61P 9/10 2006.01
A生活必需品
61医学または獣医学;衛生学
P化合物または医薬製剤の特殊な治療活性
9循環器系疾患の治療剤
10虚血,アテローム性動脈硬化症の治療のためのもの,例.抗アンギナ,冠状動脈拡張剤,心筋梗塞,網膜症,脳血流障害,腎臓細動脈硬
CPC
A61K 38/38
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
38Albumins
A61K 38/385
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
38Albumins
385Serum albumin
A61K 47/60
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
56the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
59obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
60the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
A61K 47/643
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
51the non-active ingredient being a modifying agent
62the modifying agent being a protein, peptide or polyamino acid
64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
643Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
出願人
  • 学校法人慶應義塾 KEIO UNIVERSITY [JP/JP]; 〒1088345 東京都港区三田二丁目15番45号 Tokyo 15-45, Mita 2-chome, Minato-ku, Tokyo 1088345, JP (AllExceptUS)
  • 末松誠 SUEMATSU, Makoto [JP/JP]; JP (UsOnly)
  • 萬代新太郎 MANDAI, Shintaro [JP/JP]; JP (UsOnly)
発明者
  • 末松誠 SUEMATSU, Makoto; JP
  • 萬代新太郎 MANDAI, Shintaro; JP
代理人
  • 小林浩 KOBAYASHI, Hiroshi; 〒1040028 東京都中央区八重洲二丁目8番7号福岡ビル9階 阿部・井窪・片山法律事務所 Tokyo c/o ABE, IKUBO & KATAYAMA, Fukuoka Bldg. 9th Fl. 8-7, Yaesu 2-chome, Chuo-ku, Tokyo 1040028, JP
優先権情報
60/778,48901.03.2006US
公開言語 (言語コード) 日本語 (JA)
出願言語 (言語コード) 日本語 (JA)
指定国 (国コード)
発明の名称
(EN) NOVEL ANTITHROMBOTIC AGENT
(FR) NOUVEL AGENT ANTITHROMBOTIQUE
(JA) 新規抗血栓薬
要約
(EN)
Disclosed is a pharmaceutical composition comprising polyethylene glycol-bound albumin. Also disclosed is a method for antithrombotic therapy in a human body or a method for treatment of an ischemic disease in a human body, comprising administering polyethylene glycol-bound albumin to a patient intravenously.
(FR)
La présente invention concerne une composition pharmaceutique comprenant de l'albumine liée à du polyéthylène glycol. La présente invention concerne également une méthode de thérapie antithrombotique d'un organisme humain ou une méthode de traitement d'une maladie ischémique d'un organisme humain, ladite méthode comprenant l'administration intraveineuse d'albumine liée à du polyéthylène glycol à un patient.
(JA)
本発明はポリエチレングリコール結合アルブミンを含む医薬組成物、およびポリエチレングリコール結合アルブミンを患者に静脈内投与することを含む、ヒト虚血性疾患の治療方法を提供する。
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