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1. WO2005010529 - 非特異吸着を抑制した基材表面

公開番号 WO/2005/010529
公開日 03.02.2005
国際出願番号 PCT/JP2004/011123
国際出願日 28.07.2004
IPC
G01N 33/543 2006.01
G物理学
01測定;試験
N材料の化学的または物理的性質の決定による材料の調査または分析
33グループG01N1/00~G01N31/00に包含されない,特有な方法による材料の調査または分析
48生物学的材料,例.血液,尿;血球計
50生物学的材料,例.血液,尿,の化学分析;生物学的特異性を有する配位子結合方法を含む試験;免疫学的試験
53免疫分析;生物学的特異的結合分析;そのための物質
543免疫化学物質を固定化するための不溶性担体によるもの
CPC
C12Q 1/6834
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6813Hybridisation assays
6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
C12Q 1/6837
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6813Hybridisation assays
6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
6837using probe arrays or probe chips
G01N 27/327
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
26by investigating electrochemical variables; by using electrolysis or electrophoresis
28Electrolytic cell components
30Electrodes, e.g. test electrodes; Half-cells
327Biochemical electrodes ; , e.g. electrical or mechanical details for in vitro measurements
G01N 27/3271
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
26by investigating electrochemical variables; by using electrolysis or electrophoresis
28Electrolytic cell components
30Electrodes, e.g. test electrodes; Half-cells
327Biochemical electrodes ; , e.g. electrical or mechanical details for in vitro measurements
3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
G01N 33/543
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
G01N 33/54366
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
54366Apparatus specially adapted for solid-phase testing
出願人
  • 学校法人東京理科大学 TOKYO UNIVERSITY OF SCIENCE, EDUCATIONAL FOUNDATION [JP]/[JP] (AllExceptUS)
  • 長崎 幸夫 NAGASAKI, Yukio [JP]/[JP] (UsOnly)
  • 高橋 唯仁 TAKAHASHI, Tadahito [JP]/[JP] (UsOnly)
  • 片岡 一則 KATAOKA, Kazunori [JP]/[JP] (UsOnly)
  • 網干 史子 ABOSHI, Fumiko [JP]/[JP] (UsOnly)
  • 加藤 美紀 KATO, Miki [JP]/[JP] (UsOnly)
  • 城村 友子 JOMURA, Tomoko [JP]/[JP] (UsOnly)
  • 小林 宏 KOBAYASHI, Hiroshi [JP]/[JP] (UsOnly)
  • 勝山 吉徳 KATSUYAMA, Yoshinori [JP]/[JP] (UsOnly)
  • 中前 雅美 NAKAMAE, Masami [JP]/[JP] (UsOnly)
発明者
  • 長崎 幸夫 NAGASAKI, Yukio
  • 高橋 唯仁 TAKAHASHI, Tadahito
  • 片岡 一則 KATAOKA, Kazunori
  • 網干 史子 ABOSHI, Fumiko
  • 加藤 美紀 KATO, Miki
  • 城村 友子 JOMURA, Tomoko
  • 小林 宏 KOBAYASHI, Hiroshi
  • 勝山 吉徳 KATSUYAMA, Yoshinori
  • 中前 雅美 NAKAMAE, Masami
代理人
  • 小田島 平吉 ODAJIMA, Heikichi
優先権情報
2003-30796428.07.2003JP
2003-43697429.12.2003JP
公開言語 (言語コード) 日本語 (JA)
出願言語 (言語コード) 日本語 (JA)
指定国 (国コード)
発明の名称
(EN) SURFACE OF BASE MATERIAL BEING INHIBITED IN NON-SPECIFIC ADSORPTION
(FR) SURFACE DE MATERIAU DE BASE RENDUE INSENSIBLE A UNE ADSORPTION NON SPECIFIQUE
(JA) 非特異吸着を抑制した基材表面
要約
(EN)
A surface of a base material which has a substance for detecting a material to be analyzed or a material to be analyzed being fixed thereon and have been formed by the treatment with a fluid containing a non-crosslinked polymer on the basis of a polyethylene glycol chain segment carried out simultaneously with or after the fixation of said substance or the material to be analyzed. The above surface allows the significant inhibition of the non-specific adsorption of a trashy protein and the like having been co-present in a measured sample.
(FR)
La surface d'un matériau de base comporte une matière permettant de détecter une substance à analyser, ou une matière à analyser fixée sur ladite surface, et a été formée par traitement à l'aide d'un fluide contenant un polymère non réticulé renfermant un segment de chaîne de polyéthylène glycol, ledit traitement étant mis en oeuvre simultanément ou consécutivement à la fixation de ladite matière ou de la substance à analyser. Cette surface permet d'inhiber sensiblement l'adsorption non spécifique d'une protéine impure ou analogue, présente de façon concomitante dans un échantillon mesuré.
(JA)
被分析物を検出するための物質または被分析物が固定された基材表面であって、基材表面に該物質または被分析物と同時にか、または該表面に該物質または被分析物が固定された後に、ポリエチレングリコール鎖セグメントをベースにする非架橋ポリマー含有液で処理して形成された基材表面が提供される。測定された試料中に共存する夾雑タンパク質等の非特異吸着が有意に抑制される。
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