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1. EP3336556 - FLOW PATH STRUCTURE, MEASUREMENT UNIT, METHOD FOR MEASURING LIQUID TO BE MEASURED, AND DEVICE FOR MEASURING LIQUID TO BE MEASURED

注意: このテキストは、OCR 処理によってテキスト化されたものです。法的な用途には PDF 版をご利用ください。
Claims

1. A channel structure comprising a liquid storage having a liquid container portion capable of storing liquid and an outlet portion, a separation-element housing having arranged therein a separation element between two open ends thereof, a supply channel connected to the outlet portion of the liquid storage and the one open end of the separation-element housing and causing the liquid storage and the separation-element housing to communicate with one another, and a discharge channel connected to the other open end of the separation-element housing,
wherein the supply channel includes a liquid-storage-side channel connected to the outlet portion of the liquid storage, a separation-element-side channel connected to the separation-element housing, and an injection portion located between the liquid-storage-side channel and the separation-element-side channel and being capable of introducing liquid to be measured into the supply channel, and
wherein the liquid storage includes a pressure transmission portion capable of transmitting an external force applied to the channel structure, as a variation in a pressure in the liquid storage, and is capable of causing liquid stored in the liquid storage to flow out from the outlet portion to the supply channel on the basis of the variation in the pressure in the liquid storage.
  2. The channel structure according to claim 1, wherein the channel structure is formed of a bonded body of a plurality of plate-shaped base members.
  3. The channel structure according to claim 1 or 2, wherein the pressure transmission portion is a tubular body communicating with the inside of the liquid storage and the outside of the channel structure, and the pressure in the liquid storage can be increased by a pressure of a fluid to be supplied from outside the channel structure into the tubular body.
  4. The channel structure according to any one of claims 1 to 3, wherein the pressure transmission portion has a direct-acting structure, and the pressure in the liquid storage can be increased by a force applied from outside the channel structure to the direct-acting structure.
  5. The channel structure according to any one of claims 1 to 4, wherein the separation element is a separation column.
  6. The channel structure according to any one of claims 1 to 4, wherein the separation element is an electric migration element.
  7. The channel structure according to any one of claims 1 to 6, wherein an input portion capable of inputting liquid into the liquid container portion of the liquid storage is provided.
  8. The channel structure according to any one of claims 1 to 7, wherein a vent capable of discharging gas in the liquid container portion of the liquid storage is provided.
  9. The channel structure according to any one of claims 1 to 8, wherein a porous body promoting mixing of the liquid to be measured with liquid from the liquid storage is arranged in the injection portion.
  10. The channel structure according to claim 9, wherein the porous body arranged in the injection portion has a function of promoting separation of the liquid to be measured in cooperation with the separation element.
  11. The channel structure according to any one of claims 1 to 10, further comprising a rectifying portion arranged at the liquid-storage-side channel and decreasing a variation in a flow rate of liquid flowing in the injection portion.
  12. The channel structure according to any one of claims 1 to 11, wherein a plurality of the liquid storages and a plurality of the liquid-storage-side channels connected to the plurality of liquid storages are provided, and the supply channel includes a convergence portion arranged between outlet portions of the plurality of liquid storages and the separation-element-side channel, converging the plurality of liquid-storage-side channels, and causing the plurality of liquid storages to communicate with the separation-element-side channel.
  13. The channel structure according to claim 12, wherein a porous body promoting mixing of liquid from the plurality of liquid storages is arranged in the convergence portion.
  14. The channel structure according to claim 13, wherein the porous body arranged in the convergence portion has a function of promoting separation of the liquid to be measured in cooperation with the separation element.
  15. The channel structure according to any one of claims 12 to 14, further comprising an individual rectifying portion arranged between the outlet portion and the convergence portion and decreasing a variation in a flow rate of liquid flowing in the convergence portion.
  16. The channel structure according to any one of claims 12 to 15, wherein the injection portion is integrally provided with the convergence portion.
  17. The channel structure according to any one of claims 1 to 16, further comprising a waste-liquid storage connected to an open end of the discharge channel opposite to an open end of the discharge channel connected to the separation-element housing, and storing liquid passing through the separation element.
  18. The channel structure according to claim 17, wherein the waste-liquid storage has a vent discharging gas in the waste-liquid storage.
  19. The channel structure according to any one of claims 2 to 18,
wherein at least one of the plurality of plate-shaped base members forming the bonded body transmits measurement light in a wavelength range emitted for measuring the liquid to be measured, and
wherein the discharge channel includes a channel portion extending in a thickness direction of the bonded body.
  20. The channel structure according to any one of claims 2 to 19, wherein a distance between a portion of the liquid container portion of the liquid storage being the closest to one of principal surfaces of the bonded body and the one of the principal surfaces of the bonded body is smaller than a distance between a portion of the separation-element housing being the closest to the one of the principal surfaces of the bonded body and the one of the principal surfaces of the bonded body.
  21. The channel structure according to any one of claims 2 to 20, wherein the plate-shaped base members are three or more plate-shaped base members.
  22. The channel structure according to claim 21,
wherein the liquid storage is formed by removing a portion of at least two of the plate-shaped base members, and the separation-element housing is formed by removing a portion of at least two of the plate-shaped base members, and
wherein the at least two of the plate-shaped members forming the liquid storage are different from the at least two of the plate-shaped members forming the separation-element housing.
  23. A measurement unit comprising:

the channel structure according to any one of claims 2 to 22; and

liquid stored in the liquid container portion of the channel structure.


  24. A method of measuring liquid to be measured comprising:

inputting liquid to be measured to the injection portion of the measurement unit according to claim 23;

applying an external force to the pressure transmission portion, supplying a developing solution in the liquid container portion into the supply channel, and causing liquid containing the liquid to be measured to pass through the inside of the separation element; and

measuring liquid containing the liquid to be measured passing through the separation element, and obtaining information on a composition of the liquid to be measured.


  25. The method of measuring liquid to be measured according to claim 24,
wherein at least one of the plurality of plate-shaped base members forming the bonded body transmits measurement light in a wavelength range emitted for measuring the liquid to be measured, and
wherein the information on the composition of the liquid to be measured is obtained by irradiating liquid containing the liquid to be measured passing through the separation element and located in the discharge channel, with the measurement light.
  26. The method of measuring liquid to be measured according to claim 24 or 25, wherein the separation element is a separation column, and a pressure of liquid to be supplied to the separation column is 1 MPa or lower.
  27. A measurement device for liquid to be measured comprising the measurement unit according to claim 23.