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Results 1-10 of 7,136 for Criteria: Office(s):all Language:EN Stemming: true maximize
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TitleCtrPubDate
Int.ClassAppl.NoApplicantInventor
1. WO/2016/114714 METHOD AND APPARATUS FOR FORMING BARBED SUTURESWO21.07.2016
A61B 17/04
PCT/SG2015/000013RACER TECHNOLOGY PTE LTDKOH, Kee Joo, Willy
An apparatus for forming barbed sutures, the apparatus comprising: a suture frame configured for presenting a plurality of lengths of suture on which barbs are to be formed; a bending mechanism configured to bend the plurality of lengths of suture to present a bent part of each length of suture for cutting; a cutting assembly configured to cut into a convex surface of the bent part of each length of suture to form a barb on the bent part of each length of suture; an indexing block configured to support the suture frame and the cutting assembly, the indexing block comprising an indexing mechanism configured to lock the suture frame and the cutting assembly in a cutting position and to effect relative stepwise movement between the suture frame and the cutting assembly to allow a plurality of barbs to be formed at intervals apart on each length of suture.

2. WO/2016/114717 AN ENHANCED MEASUREMENT SYSTEM OF A PHOTO-IONIZATION DETECTOR WITH CAPABILITIES FOR AUTOMATIC CLEANING AND AUTOMATIC PURGING FEATUREWO21.07.2016
G01N 27/62
PCT/SG2015/050003R2CD HOLDINGS PTE LTDCHAN, Wai Hoe
A purging and continuous measurement system for use with a Photo-Ionization Detector (PID) is disclosed. The system has a first conduit (20) for inflow of ambient gas at port (16) to be measured, during a measurement cycle, in an ionization chamber (10) of the PID, a pump (48), a second conduit (22) for flow of ambient air at port (18), and a cleaning chamber (10) of the PID which removes pollutants and contaminants in the ambient air, and a first valve (30A) for direct flow of ambient gas (16) or ambient air at port (18) into the ionization chamber (10) and a second valve (30B) for cleaned and filtered ambient gas at port (16) and ambient air at port (18) be flushed out air borne pollutants and contaminants left in the ionization chamber (10) by the ambient gas at port (16) after the measurement cycle, characterized in that the first valve (30A) is positioned in such a way that the first conduit (20) and the second conduit (22) entering the first valve (30A) and an exit from the first valve (30A) to the ionization chamber (10), and the second valve (30B) is positioned to the pump (48) and to an outflow conduit (26) into the atmosphere, and to the first conduit (20); during a measurement cycle in the first cycle, ambient gas at port (16) is drawn through the ionization chamber (10) by the operation of the pump (48), and during a second cycle which is a cleaning and a purging cycle, ambient air at port (18) is being cleaned in the cleaning chamber (12) and drawn to flush out air borne contaminants and pollutants in the ionization chamber (10), originating from the ionization of ambient gas at port (16) during the measurement cycle, and purges out through port (16) via the outflow conduit (20).

3. WO/2016/114713 DRUG ORDERING PROCESSWO21.07.2016
G06Q 50/24
PCT/SG2015/000010MHC MEDICAL NETWORK PTE LTDLOW, LeeYong
There is provided a method performed by an mobile phone application to simplify the drug ordering process, comprising display of a plurality of products for selection by a user; enabling the addition and subtraction of quantities of products into a shopping cart; and sending the orders in a shopping cart to the respective distributors.

4. WO/2016/114716 ELECTRONIC DEVICE GRADE SINGLE CRYSTAL DIAMONDS AND METHOD OF PRODUCING THE SAMEWO21.07.2016
C01B 31/06
PCT/SG2015/000145IIA TECHNOLOGIES PTE LTDDEVI, Shanker Misra
A method utilising microwave plasma chemical vapour deposition (MPCVD) process of producing electronic device grade single crystal diamond comprising of: (a) selecting a diamond seed or substrate having a pre-determined orientation, (b) cleaning and / or etching of non-diamond phases and other induced surface damages from the diamond seed or substrate, whereby this step can be performed one or more times, (c) growing a layer of extremely low crystal defect density diamond surface on the cleaned / etched diamond seed or substrate, whereby this step can be performed one or more times, and (d) growing electronics device grade single crystal diamond on top of the layer of the low crystal defect density diamond surface.

5. WO/2016/114718 MEMORY DEVICE AND METHOD FOR OPERATING THEREOFWO21.07.2016
H01L 27/105
PCT/SG2015/050520AGENCY FOR SCIENCE,TECHNOLOGY AND RESEARCHFOONG, Huey Chian
According to various embodiments, there is provided a memory device including at least one sense amplifier having a first side and a second side, wherein the second side opposes the first side; a first array including a plurality of memory cells arranged at the first side; a second array including a plurality of memory cells arranged at the second side; a first row including a plurality of mid-point reference units arranged at the first side; and a second row including a plurality of mid-point reference units arranged at the second side, wherein each mid-point reference unit of the first row is configured to generate a first reference voltage, and wherein each mid-point reference unit of the second row is configured to generate a second reference voltage; wherein the sense amplifier is configured to determine a resistance state of a memory cell of the first array based on the second reference voltage; wherein the sense amplifier is configured to determine a resistance state of a memory cell of the second array based on the first reference voltage.

6. WO/2016/114723 DIFFERENTIATION OF MACROPHAGES FROM PLURIPOTENT STEM CELLSWO21.07.2016
C12N 5/0786
PCT/SG2016/050018AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHLIM, Hwei-In Shawn
The present invention relates to a method of culturing primitive-like macrophages from stem cells, a kit when used in the method thereof and uses of the primitive like macrophage for in-vitro disease models and for screening compounds for therapy. One embodied culture method comprises contacting and incubating embryonic stem cells or induced pluripotent stem cells with a serum-free culture media comprising a GSK3 inhibitor to differentiate stem cells into cells of the mesoderm lineage, followed by incubation with a culture media comprising Dickkopf-related protein 1 (DKK1) to differentiate the mesoderm into cells of hematopoietic lineage, maturing hematopoietic cells and incubating these cells with a culture media comprising M-CSF to drive differentiation into primitive-like macrophages. Another embodiment comprises incubating the stem cells with serum-free culture media comprising FGF2 and BMP4 to induce differentiation into cells of the mesoderm lineage, followed by incubating the cells with a culture media comprising FGF2, BMP4, Activin A and VEGF to differentiate the cells of the mesoderm lineage into cells of the hematopoietic cell lineage, maturing the cells of the hematopoietic cell lineage and lastly, incubating the matured hematopoietic cells with culture media comprising M-CSF to drive the differentiation of hematopoietic cells into primitive-like macrophages.

7. WO/2016/114721 METHOD AND SYSTEM FOR MAKING A SECURE PAYMENT TRANSACTIONWO21.07.2016
G06Q 20/22
PCT/SG2016/050014MASTERCARD ASIA/PACIFIC PTE LTDVENUGOPALAN, Vijin
A method and system are presented for making a secure payment transaction using a payment card associated with a consumer which has been registered with a digital wallet. A secure server is arranged, in response to a request from a merchant server in relation to the consumer, to extract from the digital wallet payment credentials for the payment card. The secure server uses the payment credentials and the identity of the merchant server to generate a token. The token is provided to the merchant. To effect a payment transaction, the merchant server returns the token to the secure server with details of the desired payment transaction, and the secure server arranges for the payment transaction to occur, and notifies the merchant server. The merchant server does not receive the payment credentials of the payment card during this process, so even if its security is compromised, the payment credentials are not at risk.

8. WO/2016/114719 PERCUTANEOUS CAVAL VALVE IMPLANTATION FOR SEVERE TRICUSPID REGURGITATIONWO21.07.2016
A61F 2/07
PCT/SG2016/050012NATIONAL UNIVERSITY OF SINGAPORETAY, Lik Wui Edgar
Implantable prosthetic valves and related methods for treating tricuspid valve regurgitation block transmission of elevated pressure during ventricular systole upstream along the superior vena cava and the inferior vena cava. A method for treating tricuspid valve regurgitation includes implanting a first prosthetic valve into the superior vena cava adjacent to the junction of the superior vena cava and the right atrium and implanting a second prosthetic valve into the inferior vena cava adjacent to the junction of the inferior vena cava and the right atrium. The implanted first and second prosthetic valves accommodate blood flow to the right atrium and block back flow of blood from the right atrium, thereby decreasing pressure within the superior vena cava and within the inferior vena cava. In many embodiments, the first and second prosthetic valves are configured to accommodate blood flow from one or more adjacent veins covered by the respective implanted valve.

9. WO/2016/114722 ALPHA-CELL SELECTIVE PROBE FOR EX-VIVO TWO PHOTON IMAGING OF ALPHA CELLS IN INTACT PANCREATIC ISLETSWO21.07.2016
C07C 237/10
PCT/SG2016/050016NATIONAL UNIVERSITY OF SINGAPORECHANG, Young-Tae
The present invention relates to a composition represented by structural formula (A) [Formula should be entered here] or a salt thereof, as well as a method of visualizing a target cell, the method including (a) contacting a population of the target cell with the composition to form an incubation media, (b) incubating the incubation media for a period of time sufficient to stain the target cells, and (c) visualizing the stained target cells with two-photon microscopy to visualize the target cell.

10. WO/2016/114720 MONOCLONAL ANTIBODY AGAINST MURAMYL PEPTIDES IN PREVENTION AND TREATMENT OF IMMUNE-MEDIATED DISEASESWO21.07.2016
A61K 39/02
PCT/SG2016/050013AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHWANG, Yue
Disclosed are methods of treating an autoimmune or inflammatory disease using a composition comprising an isolated antibody or an antigen-binding fragment or variant thereof that is capable of binding to muramyl peptide, derivative, analog or salt thereof, wherein said muramyl peptide comprises muramic acid and an amino acid selected from the group consisting of alanine, isoglutamine, glutamic acid and a salt thereof. In one preferred embodiment, the composition can comprise of the isolated antibody or an antigen-binding fragment and one or more therapeutic agents such as Tumor Necrosis Factor (TNF) inhibitor. The autoimmune or inflammatory disease is selected from a group consisting of sepsis, septic shock, Crohn's disease, rheumatoid arthritis, asthma, allergy, atopic disorders, multiple sclerosis, pertussis, gonorrhea, inflammatory bowel disease, and antibiotic associated disorder.


Results 1-10 of 7,136 for Criteria: Office(s):all Language:EN Stemming: true
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