WO/2016/078660 DETECTING REPLICATION CATASTROPHE IN CELLS||WO||26.05.2016|
||PCT/DK2014/050394||KØBENHAVNS UNIVERSITET ||LUKAS, Jiri |
The present invention relates to methods for determining the status in a cell. In particular the present invention relates to methods for determining whether a cell population will undergo replication catastrophe in response to a cancer therapy. The invention also relates to methods of treatment of cancer.
WO/2016/078665 A CONTAMINANT SENSOR FOR DETECTING MAGNETIZABLE CONTAMINANTS IN LUBRICANT FLOW||WO||26.05.2016|
||PCT/DK2015/050350||VESTAS WIND SYSTEMS A/S ||NIELSEN, Thomas Korsgaard |
A contaminant sensor (1) for detecting magnetizable contaminants (7) present in a lubricant flow is disclosed. A permanent magnet (3) is arranged movably inside a sensor housing (2). A sensor element (6, 11, 13), e.g. in the form of a distance sensor (6) or a pressure sensor (11), is arranged to detect a displacement of the permanent magnet (3) inside the sensor housing (2), and an indicator is arranged to generate an alert signal when a displacement and/or a rate of change of displacement of the permanent magnet (3) inside the sensor housing (2) exceeds a predefined threshold value. The permanent magnet (3) is arranged to move inside the sensor housing (2) in response to magnetizable contaminants (7) collected on an outer surface of the sensor housing (2).
WO/2016/078663 CURTAILED OPERATION OF A WIND POWER PLANT BY DEACTIVATION OF WIND TURBINES||WO||26.05.2016|
||PCT/DK2015/050342||VESTAS WIND SYSTEMS A/S ||MØLLER, Henrik |
The invention relates to a method for operating a group of wind turbines in a wind power plant coupled to a utility grid, comprising the steps of determining that a wind turbine should be deactivated in response to receiving a power curtailment command from the grid, and retrieving data from each wind turbine in the group of wind turbines. Further, the method comprises ranking all the wind turbines according to a set of ranking criteria and based on the retrieved data, and selecting a wind turbine to be deactivated based on the ranking. Further, the steps of data retrieval and ranking of all the wind turbines including any deactivated wind turbines in the group are repeated at time intervals, and the wind turbine to be deactivated is re-selected based on this updated ranking. The data may include a down time for any presently deactivated wind turbine in the group of wind turbines, reflecting for how long time the wind turbine has been presently deactivated, and the set of ranking criteria may then comprise a pause criterion taking into account the down time.
WO/2016/078667 ASSEMBLY FOR ASSESSING DRUG PERMEABILITY WITH ADJUSTABLE BIOMIMETIC PROPERTIES||WO||26.05.2016|
||PCT/DK2015/050352||SYDDANSK UNIVERSITET ||DI CAGNO, Massimiliano Pio |
There is provided an assembly and process for its preparation for predicting the permeability of chemical compounds,comprising a donor compartment for adding a composition comprising the compound;a barrier based on a support and a phospholipid layer adhering to the support; and an acceptor compartment for accepting the compound upon permeation of the barrier.
WO/2016/078670 DETECTING REPLICATION CATASTROPHE IN CELLS||WO||26.05.2016|
||PCT/DK2015/050355||KØBENHAVNS UNIVERSITET ||LUKAS, Jiri |
The present invention relates to methods for determining the status in a cell. In particular the present invention relates to methods for determining whether a cell population will undergo replication catastrophe in response to a cancer therapy. Further aspects relate to methods for classification of a compound of interest based on said compounds effect on amounts of DB-RPA and DNA damage in a cell nucleus. The invention also relates to methods of treatment of cancer.
WO/2016/078673 PROCESS FOR REDUCING THE OXYGEN CONTENT OF BIOMASS USING MOLYBDENUM-BASED CATALYSTS||WO||26.05.2016|
||PCT/DK2015/050359||DANMARKS TEKNISKE UNIVERSITET ||DETHLEFSEN, Johannes Rytter |
The present invention concerns a process for converting biomass into useful organic building blocks for the chemical industry. The process involves the reduction of a polyol wherein at least two of the hydroxyl groups are located on adjacent carbon atoms in the presence of a molybdenum-based catalyst of the formula (I), such as (ΝΗ4)6Μo7O24⋅4Η20. A primary or secondary monohydric C1-C4 alcohol is used as reductant, as well as a solvent.
WO/2016/078668 A METHOD FOR ESTIMATING A WIND SPEED IN A STABLE MANNER||WO||26.05.2016|
||PCT/DK2015/050353||VESTAS WIND SYSTEMS A/S ||ATZLER, Martin |
A method for iteratively estimating a wind speed at a wind turbine is disclosed, said wind turbine comprising a rotor carrying a set of wind turbine blades, each wind turbine blade having a variable pitch angle. A minimum tip speed ratio, λmin, is derived, based on an obtained pitch angle, θ. The minimum tip speed ratio, λmin, defines a limit between a stable and an unstable control region. An initial tip speed ratio, λinit> λmin, is selected, and an initial estimated wind speed, vinit, is derived based on the initial tip speed ratio, λint, and an obtained rotational speed, ω, of the rotor. An estimated wind speed, vest, is iteratively derived, based on the obtained rotational speed, ω, and the obtained pitch angle,ω, and using the derived initial estimated wind speed, vinit, as a starting point. The iterative process converges fast and reliably.
WO/2016/078671 CIRCULATING SUB WITH ACTIVATION MECHANISM AND A METHOD THEREOF||WO||26.05.2016|
||PCT/DK2015/050356||ADVANCETECH APS ||SOLEM, Sigurd |
The present invention relates to an activation method, an activation mechanism and a downhole tool comprising the activation mechanism. The activation mechanism com- prises a pressure switch for turning power to the electrical components, a control unit connected to a pressure sensor for sensing the internal pressure of the drilling fluid located in a first fluid conduit. The control unit controls an actuator unit connected to a moveable valve element. The actuator unit moves the valve element from a closed position when activated. A seat for the valve element is arranged relative to a second fluid conduit so that the valve element closes the second conduit when it is placed in its seat. This provides a very fast and accurate activation method that involves the use of balls or RFID tags. Furthermore, the downhole tool can be activated even if no actual flow is passing through the tool.
WO/2016/078672 TNF-ALPHA INHIBITOR FOR TREATING STROKE||WO||26.05.2016|
||PCT/DK2015/050358||SYDDANSK UNIVERSITET ||LAMBERTSEN, Kate Lykke |
The present disclosure is directed to a method of treating stroke and/or symptoms associated with stroke by administration to a subject in need thereof a DN -TNF polypeptide that inhibits the activity of soluble TNF- but not transmembrane TNF-α.
WO/2016/078666 AN UNBONDED FLEXIBLE PIPE AND A METHOD FOR REGULATING THE TEMPERATURE OF THE SURFACE OF AN UNBONDED FLEXIBLE PIPE||WO||26.05.2016|
||PCT/DK2015/050351||NATIONAL OILWELL VARCO DENMARK I/S ||GLEJBØL, Kristian |
The invention relates to an unbonded flexible pipe (1) having a length and a longitudinal direction (10) along the length and comprising from the inside and out at least an internal pressure sheath (2) defining a bore (11), on or more armour layers (3,4,5) and an outer sheath (7), wherein the unbonded flexible pipe (1) in at least a length section comprises at least one tube (8) wound around the outer sheath (7) with an inclination of at least 60° in respect of the longitudinal direction (10). The tube (8) has a first end and a second end, wherein the first end of the tube (8) is adapted for connection to a fluid source. A protective layer (9) may surround the tube (8). The invention also relates to a method for regulating the temperature of the surface of an unbonded flexible pipe.