WO/2015/176693 DEVICE FOR A MANIPULATION WITH A CONTACT LENS WITHIN AN EYE AREA AND A METHOD OF MANUFACTURING SUCH DEVICE||WO||26.11.2015|
||PCT/CZ2015/000046||PALASOVÁ, Lucie ||PALASOVÁ, Lucie |
Device for a manipulation with a contact lens within an eye area and methods for the production thereof The invention concerns a device for a manipulation with a contact lens within an eye area and methods for the production thereof, the subject matter of which lies in that it comprises a functional part (1) from porous polymer, mainly hydrophilic polymer, which is shaped for a non-aggressive contact with the cleaned area of the eye and adapted by its porousness for absorption of non-toxic and non-irritant fluid, as well as methods for producing said device.
WO/2015/176692 ROTARY MOTOR WITH GEARED TRANSMISSION FOR USE OF COMPRESSIBLE MEDIA DRIVE||WO||26.11.2015|
||PCT/CZ2015/000041||DVOŘÁK, Jiří ||DVOŘÁK, Jiří |
A rotary motor with a geared transmission for use of compressible media drive which contains a stator (1) which is procured with at least one, preferably two, triangular cavities (12) which are sealed to surrounding environment and which are procured with rounded peaks (121) from which into each is led in at least one canal (41) for entry and exit of compressible medium where in each cavity (12) is embedded a rotary piston (2) with en elliptical crosscut in the way that its lengthwise axis (Op) which is parallel with an axis (Oc) of a rotary element (7) is displaced regarding to a lengthwise axis (Os) of the inner cavity (12) of the stator (1) of a value of eccentricity (e) in order to reach a planetary movement of the rotary piston (2) namely during the displacement of the lengthwise axis (Op) of the rotary piston (2) along a circle with radius of the eccentricity (e) where the essence of the invention is in the fact that the mutual coupling of the rotary pistons (2) with a driven mechanism (9) is achieved by led out of following pins (21) of the rotary pistons (2) out of the cavities (12) of the stator (1) where they are procured with rotary cog wheels (6) which are mutually coupled with the geared elliptical rotary element (7) which is connected with the driven mechanism (9).
WO/2015/172754 DEVICE FOR POSITIONING INTERIOR BLIND SLATS||WO||19.11.2015|
||PCT/CZ2015/000013||ZEBR S.R.O. |
Device for positioning of interior blinds slats, especially window blinds which consists of a hollow rod (1) with a longitudinal slot (2) and it is further provided with a brake (3) at one end and with a pass-through joint (4) with pins (5) provided for fastening at an end piece (6) of a bearing profile (7) at another end, of a slider (15) arranged slidingly on the hollow rod (1) and which is led by a shoulder (16) and by the longitudinal slot (2) inside of the hollow rod (2), whereas in the hollow rod (1) passages (17,18) are arranged on the slider's shoulder (16) for the bendable member (13) and into the passage (17) arranged on the side of the longitudinal slot (2) a pressure button (19) which protrudes slidingly into the slider (15), is arranged.
WO/2015/169271 VACCINE FOR PREVENTION OF LYME BORRELIOSIS||WO||12.11.2015|
||PCT/CZ2015/000042||VYZKUMNY USTAV VETERINARNIHO LEKARSTVI, V.V.I. ||TURANEK, Jaroslav |
The invention provides a vaccine for prevention of Lyme borreliosis containing at least two types of chimeric poly epitope recombinant antigens, comprising immunodominant regions of OspA and OspC antigens, and at least one adjuvant and/or ferritin II.
WO/2015/169270 LIGHT SOURCE||WO||12.11.2015|
||PCT/CZ2015/000040||CRYTUR, SPOL.S R.O. ||FIDLER, Tomáš |
The light source (1) is based on a high-efficiency solid-state laser source (2) of the excitation coherent radiation (3) and a single crystal phosphor (4) which is machined in a form of an optic element for emitted light parameterisation. The single crystal phosphor (4) is produced from a single crystal material on the basis of garnets of the (Ax, Lu1-x)aAlbO12:Cec general formula or from a single crystal material on the basis of perovskite structure of the B1-qAIO3:Dq general formula. The efficient light source (1) shall be utilized e.g. in the automotive industry.
WO/2015/169269 SALTS OF 2-CHLORO-N-(4-CHLORO-3-(PYRIDIN-2-YL)PHENYL)-4-(METHYLSULFONYL)BENZAMIDE||WO||12.11.2015|
||PCT/CZ2014/000049||ZENTIVA, K.S. ||RIDVAN, Ludek |
A salt comprising compound of Formula (I) and at least one acid component (HA).
WO/2015/165428 FUROPYRIDINES AS INHIBITORS OF PROTEIN KINASES||WO||05.11.2015|
||PCT/CZ2015/000038||MASARYKOVA UNIVERZITA ||PARUCH, Kamil |
The invention relates to furo[3,2-b]pyridines substituted at least in position 5 as inhibitors of protein kinases, regulators or modulators, methods of preparation thereof, pharmaceutical compositions containing the compounds, and pharmaceutical use of the compounds and compositions in the treatment of the diseases such as, for example, cancer or neurodegenerative diseases. (Formula (I))
WO/2015/161834 METHOD OF MANUFACTURING LAMINATE AND THE LAMINATE||WO||29.10.2015|
||PCT/CZ2014/000042||MERIT CHAIN LIMITED ||TETHAL, Tomas |
A method of manufacturing laminate, comprising of at least two layers (1, 5) of thermoplastic materials with a diffractive optical element incorporated between them. In this method a layer (2) with a different refraction index from that of a carrying layer (1) and/or from that of a cover layer (5) of thermoplastic material is put on a carrying layer (1) and covered by the cover layer (5). The layer (2) with a different refraction index is placed only in some areas of the carrying layer (1). Subsequently a stamp (4) with optical diffractive relief (6) is imprinted and/or embossed into the layer (2) with a different refraction index. Then the cover layer (5) of thermoplastic material is put on the layer (2) with a different refraction index and the laminate is heated to a temperature at which bonding of the cover layer (5) and the carrying layer (1) occurs. A laminate, comprising of at least two layers (1, 5) of thermoplastic materials, with optical diffraction element incorporate between them.
WO/2015/158316 AN ECOLOGICAL VEHICLE FOR TRANSPORTATION OF PERSONS||WO||22.10.2015|
||PCT/CZ2015/000036||BÖHM, František ||BÖHM, František |
An vehicle comprising one support frame with a raised higher front part, which is provided with at least two wheels (2, 3) and at least one seat (4), a control means connected with at least one steerable wheel (3) and a drive means connected to at least one driven wheel (2). The support frame forms a diagonally arranged elongated straight beam (5) forming an angle a of between 15° and 30° with the horizontal plane (6) and arranged with its rear end before the rear steerable wheel (3) and with its front end above the front driven wheel (2). Simultaneously, to the rear end of the beam (5) there is fixed an upwardly extending rear support arm (7) carrying the mounting (8) of the rear steerable wheel (3) and in the central part of the beam (5) there is fixed a downwardly extending front support arm (9) carrying the swinging fork (10) for mounting the front driven wheel (2). On the beam (5) there is further arranged a sliding mounted seat (4) with the possibility of locking a selected position of the seat (4) on the beam (5).
WO/2015/158317 USE OF A L,3J5-TRIAZIN-2-YL PHOSPHORAMIDATE COMPOUND IN THE SYNTHESIS OF SOFOSBUVIR||WO||22.10.2015|
||PCT/CZ2015/000037||ZENTIVA, K.S. ||SEFKO, Martin |
The present invention relates to a new type of 1,3.5-triazin-2-yl phosphoramidates of general formula I with the absolute configuration (S) at the phosphorus atom, an Sp diastereoisomer, wherein R1 and R2 can independently be H, a C1-C6 (un)branched alkyl, a C1-C6 (un)branched alkoxy group, a C1-C6 (un)branched alkylsulfanyl group, C1-C6 (un)branched monoalkylamino or dialkylamino group, including cyclic amino groups, e.g. pyrrolidino, piperidino or morpholino group; and to their use for the production of biologically active phosphoramidate prodrugs, especially sofosbuvir of formula II. Sofosbuvir II is a nucleotide inhibitor of the RNA polymerase, used for the treatment of hepatitis C in the form of a prodrug, releasing the active antiviral agent 2'-deoxy-2'-a-fluoro- P-C-methyluridine-5'-triphosphate in the organism.