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Results 1-10 of 2,161 for Criteria: Office(s):all Language:EN Stemming: true maximize
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TitleCtrPubDate
Int.ClassAppl.NoApplicantInventor
1. WO/2016/192689 A METHOD OF FORMING A METAL ELECTRODE ON THE CERAMIC INSULATOR OF A SPARK PLUGWO08.12.2016
H01T 21/02
PCT/CZ2015/000055BRISK TÁBOR, A.S.MOJMÍR, Čapka
The method of creating a metal electrode on the ceramic insulator of a spark plug with a deposit of additional material using the laser weld deposition method, where this metal electrode, formed by a diffusion metallic layer (3) of the joint between the weld deposit of the smelted wire and the insulator (1), is in the shape of a ring in the end part of the insulator body (1) around the central electrode (2) of the spark plug. First, the spark plug insulator (1) is preheated by resistance heating to the temperature of 500 to 700°C at the rate of 100 to 150°C/min to prevent the creation of thermal stresses, and subsequently it is exposed to rotation at the speed depending on the required wire weld deposit thickness, where the end part of the insulator (1), at a distance of 12 to 15 mm from its margin, is preheated to the temperature of the wire weld deposition determined below the temperature of phase transformation of the insulator (1) material by the action of a laser beam swept into a rectangular area homogenously at the power density of laser preheating within the range of 3,500 to 4,000 W/sq. cm. After achieving the weld depositing temperature of the wire, the wire feeding into the area of the created electrode is activated, with a feed speed from 0.5 to 3 mm / 360°, and together with the wire feeding activation, the laser output decreases to the power density of 700 to 900 W/sq. cm, while throughout the weld deposition, the end part of the insulator is simultaneously heated at a distance of 12 to 15 mm from its margin and after weld depositing an overlap of 360° + 30° of the insulator (1), the wire feeding is deactivated and the laser output is decreased to zero.

2. WO/2016/192690 EXTENSION FOR INCREASING OF THE UPPER LIMIT OF APPLICATION OF POLYURETHAN FOAM FROM A DOSEWO08.12.2016
B05B 9/08
PCT/CZ2016/000010MISLER, JaroslavMISLER, Jaroslav
Extension (1) for increasing of the upper limit of application of polyurethan foam from a dose (2) including a connection socket (3) connected with a swinging controller (4) where on the connection socket a lower bending (5) is connected, on which a tube prolongation (6) is connected, on which an upper bending (7) is connected and on it an application ending (8) is connected, where the extension (1) is provided inside with a freely arranged wire (10) for its shaping and the connection socket (3) is provided with at least one hole (13) and simultaneously there is a hook (14) in the end of the wire (10), diameter of which is smaller then the diameter of the hole (13) for inserting of the hook (14) into the connection socket (3) and both over the wire (10) and over the connection socket (3) the tube (11) is pulled over up to the foot (17) of the connection socket (3).

3. WO/2016/192691 SOLID FORMS OF DACLATASVIRWO08.12.2016
C07D 403/14
PCT/CZ2016/000058ZENTIVA, K.S.ZVATORA, Pavel
Salts of methyl [(1S)-2-{(2-S)-4-[4-(2'-{2-[(1S)-2-{(2S)-3-[(methoxycarbonyl)amino]-2- methylbutanoyl } -4-pyrrolidinyl]-1H-imidazol-4-yl } -2-biphenylyl)-1H-imidazol-1-yl] -3 - pyrrolidinyl}-1-methyl-2-oxo-2- butanyl]carbamate-daclatasvir of formula (I) in the solid state with an acid from the group consisting of hydrochloric, hydrobromic, sulphuric, 2-naphthalenesulfonic, toluenesulfonic, methanesulfonic, benzenesulfonic, maleic and fumaric acid. Preparation of the salts of daclatasvir with acids.

4. WO/2016/192692 SOLID FORMS OF TENOFOVIR ALAFENAMIDEWO08.12.2016
C07F 9/6561
PCT/CZ2016/000059ZENTIVA K.S.DAMMER, Ondrej
The invention relates to a solid form of tenofovir alafenamide with an inorganic or organic acid selected from the following group: hydrochloric, hydrobromic, sulfuric, phosphoric, maleic, citric, succinic, tartaric, gallic, benzenesulfonic, salicylic, 4- aminobenzoic acid. Another aspect of the present invention provides a pharmaceutical composition, which comprises the solid form of tenofovir alafenamide and at least one pharmaceutically acceptable excipient, the composition being used as a medicament for the treatment of HIV infection and viral hepatitis B. (I)

5. WO/2016/192693 EQUIPMENT FOR COMMUNITY RECEPTION AND DISTRIBUTION OF TELEVISION AND RADIO PROGRAMSWO08.12.2016
H04N 21/61
PCT/CZ2016/000060EMP - CENTAURI, SPOLEČNOST S RUČENÍM OMEZENÝMHAJČIAR, Petr
Problem to be resolved: Distribution of community television and radio signal is performed individually. Antennas (4, 12) of the subscribers make the concerned buildings unsightly, construction adjustments must be completed on the residential buildings and all the subscribers must purchase their own receivers (14) and decoders (15). Solution: The apparatus (13) for community reception and distribution of television and radio programs allows installation of a limited number of antennas (4, 12) on residential buildings with numerous subscribers and it allows to use the existing coaxial distribution system with star topology in the building and the apparatus (13) made according to one of the examples of practical embodiment that allows data communication.

6. WO/2016/192694 A PROCESS FOR PREPARING THE KEY INTERMEDIATE OF APREMILAST, USING ENZYMATIC RESOLUTION OF THE RACEMIC AMINESWO08.12.2016
C12P 41/00
PCT/CZ2016/000061ZENTIVA, K.S.DOUBSKY, Jan
The invention relates to a preparation method of (S)-l-(3-ethoxy-4-methoxyphenyl)- 2-(methylsulfonyl)-ethyl-amine (S)-l, or its N-acyl derivatives of general formula (S)-2. The amine (S)-l is the key intermediate in the synthesis of (S)-{2-[l-(3-ethoxy-4- methoxyphenyi)-2-methyisulfonylethyl]-4-acetylaminoisoindolin-l ?3-dione, known as Apremilast. In this synthesis, the amine (S)-l, or its respective salts, are subjected to condensation with 3-acetamidophthalic anhydride 4, providing the desired product 3 (Scheme 1).

7. WO/2016/192695 DEVICE AND METHOD FOR DETECTING THE PRESENCE OF BEDWO08.12.2016
G01S 5/02
PCT/CZ2016/000062LINET SPOL. S.R.O.HARTMAN, Marek
The device and method for determining the position of a hospital bed using wireless technology comprises a transmitter, receiver, and communication module for collecting data from the hospital bed and for forwarding packets of information from the bed to the server. For determining a bed's position, the ID of the bed is transmitted by the communication module without a unique transmitter ID. The transmitter is securely attached near the defined parking position and sends a unique identifier of the position using at least one transmitter. The receiver is attached to the hospital bed. The method allocates a bed to the parking position and is able to detect the former occupancy of the parking position and the activity of the formerly-allocated bed.

8. WO/2016/192696 METHOD OF SCANNING DEVELOPMENT OF DEFORMATIONS DURING IMPACT TESTS AND APPARATUS FOR MAKING THE SAMEWO08.12.2016
G01N 3/06
PCT/CZ2016/050016TOMAS BATA UNIVERSITY IN ZLINMALOCH, Jaroslav
In the process of scanning/registering/depicting the course of deformations in the course of impact tests, when the impact hammer or the drop hammer fall on the obverse surface of an experimental specimen, the test specimen is illuminated - and the distortion, or respectively, the destruction of their reverse surface is thus captured by a high-speed camera system during the impact of the impact hammer or of the drop hammer. The subsequent images, recorded on tape or other media, are then optimised by means of Post-processing Methods. The device, designed for performing this method, (viz Fig. 1), comprises a measuring head (1); with a test body (2); fixed to its upper surface, above the vertical central channel (la) of the head - in the area of the impact of the "impact hammer" or "drop-hammer" (3). Under the "test body" (2), are illumination channels (5) in the walls of the measuring head (1); directed toward the central channel cavity (la); which incorporate inserted light sources (4); or the outlets of externally located/vented external fibre-optic light sources; in the space under the illumination channels (5) - against the outlet of the observation channel (lb) and into the central channel (la) a mirror is placed obliquely (7); the upper reflective surface is oriented perpendicular to the axis of the angle between the axis of the side observation channel (lb) and the axis of the central channel (la); outside the side observation channel (lb), a high-speed camera system (8) is mounted on a stand (9) for scanning purposes.

9. WO/2016/192697 LINEAR FIBROUS FORMATION WITH A COATING OF POLYMERIC NANOFIBERS ENVELOPING A SUPPORTING LINEAR FORMATION CONSTITUTING A CORE, A METHOD AND A DEVICE FOR PRODUCING ITWO08.12.2016
PCT/CZ2016/050017TECHNICKA UNIVERZITA V LIBERCIBERAN, Jaroslav
The invention relates to a linear fibrous formation with a coating of polymeric nanofibers consisting of a core formed by a supporting linear formation (3) and of polymeric nanofibers. The polymeric nanofibers envelop the supporting linear formation (3) constituting a core (31) of the resulting linear fibrous formation (30) with a nanofibrous coating (32) composed of a flat formation created from a nanofibrous plume (6) withan organized structure of nanofibers generated by electrospinning using AC high electric voltage, whereby the nanofibrous coating (32) is wrapped around the core (31) with a helical-shaped stripe. In addition, the invention relates to a method for the production of a linear fibrous formation with a nanofibrous coating containing polymeric nanofibers, whose core is composed of a supporting linear formation (3). On a spinning electrode (5) powered by AC voltage is formed a nanofibrous plume (6), which in the spinning space (41) changes into a flat stripe with an organized structure of nanofibers, which is fed towards the circumference of the supporting linear formation (3) rotating in the spinning space around its own axis and/or ballooning in the spinning space with at least one antinode loop, whereby the stripe created from the nanofibrous plume (6) winds around the supporting linear formation, forming a helix around the supporting linear formation (3). The invention also relates to a device for producing a linear fibrous formation.

10. WO/2016/188506 SOLID FORMS OF 5-FLUORO-3-PHENYL-2-[(1S)-1-(9H-PURIN-6-YLAMINO)PROPYL]QUINAZOLIN-4-ONE AND PREPARATION THEREOFWO01.12.2016
C07D 473/34
PCT/CZ2016/000056ZENTIVA, K.S.KISS, Violetta
Solid forms of 5-fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)propyl]quinazolin-4-one of formula (I), suitable for oral administration, which comply with pharmaceutical requirements. Preparation and characterization of Crystal Form 1 and Crystal Form 2.


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