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1. WO2020205920 - PROTECTION DE L'INTÉGRITÉ D'ANTICORPS MONOCLONAUX CONTRE LA SOLIDIFICATION PAR ÉVAPORATION, LA COMPRESSION ET LA PROTÉOLYSE À L'AIDE DE DEXTRANE ET DE DÉRIVÉS DE LA CYCLODEXTRINE


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INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/US2020/026092 0652022 WO
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
01 April 2020 01 April 2019
Applicant
VTA LABS, LLC
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No. ____________
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     A61K 39/395 (2006.01)i; C07K 16/22 (2006.01)i; C07K 16/24 (2006.01)i; C07K 16/32 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     A61K; C07K
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data, BIOSIS, EMBASE

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
X
WO 2018019900 A1 (LAB FRANCAIS DU FRACTIONNEMENT [FR]) 01 February 2018 (2018-02-01)
1-16
cited in the application
Y
the whole document
17-20
in particular, pages 3, 10-12 and 15-17
(2)
X
EP 3459527 A1 (TILLOTTS PHARMA AG [CH]) 27 March 2019 (2019-03-27)
1,5,6
the whole document
in particular, claims 1, 3, 4 and 11
(3)
Y
WO 2004009319 A1 (SMI INC [US]) 29 January 2004 (2004-01-29)
17-20
the whole document
in particular, pages 3 and 6
(4)
A
VAHID RAMEZANI ET AL, "Application of cyclodextrins in antibody microparticles: potentials for antibody protection in spray drying", DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY,Vol. 43, No. 7, 01 March 2017 (2017-03-01), page 1103-1111,
XP055656619
1-20
the whole document
in particular, see abstract and pages 1108-1110
(5)
A
Ajay K Banga, "Therapeutic peptides and proteins: formulation, processing, and delivery systems",
ISBN: 9781466566064
15 April 2015 (2015-04-15),
Retrieved from the Internet:
URL:https://www.taylorfrancis.com/books/9780429099908
XP055499575
ISBN: 9781466566064
1-20
the whole document
in particular, section 4.4.2
(6)
A
WANG W ET AL, "ANTIBODY STRUCTURE, INSTABILITY, AND FORMULATION", JOURNAL OF PHARMACEUTICAL SCIENCES, AMERICAN CHEMICAL SOCIETY AND AMERICAN PHARMACEUTICAL ASSOCIATION, US,Vol. 96, No. 1, 01 January 2007 (2007-01-01), page 1-26,
XP009084505
1-20
the whole document
in particular, pages 18-20
(7)
A
SON SOYOUNG ET AL, "Anti-Trop2 antibody-conjugated bioreducible nanoparticles for targeted triple negative breast cancer therapy", INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, ELSEVIER BV, NL,Vol. 110, 18 October 2017 (2017-10-18), page 406-415,
XP085363539
1-20
the whole document
in particular, page 408
(8)
A
SIVASUBRAMANIAN MAHARAJAN ET AL, "Mineralized cyclodextrin nanoparticles for sustained protein delivery", CARBOHYDRATE POLYMERS, APPLIED SCIENCE PUBLISHERS, LTD. BARKING, GB,Vol. 97, No. 2, 18 May 2013 (2013-05-18), page 643-649,
XP028687313
1-20
the whole document
in particular, page 644
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
WO 2018019900 A1
01 February 2018
CA 3031033 A1
EP 3490534 A1
FR 3054444 A1
US 2019270801 A1
WO 2018019900 A1
01 February 2018
05 June 2019
02 February 2018
05 September 2019
01 February 2018
EP 3459527 A1
27 March 2019
AR 112701 A1
CA 3075875 A1
CN 111107841 A
EP 3459527 A1
EP 3684340 A1
KR 20200054984 A
TW 201914576 A
WO 2019057563 A1
27 November 2019
28 March 2019
05 May 2020
27 March 2019
29 July 2020
20 May 2020
16 April 2019
28 March 2019
WO 2004009319 A1
29 January 2004
AU 2003261210 A1
CA 2492869 A1
CN 1668439 A
EP 1536934 A1
JP 2005533563 A
KR 20050037555 A
US 2004056375 A1
WO 2004009319 A1
09 February 2004
29 January 2004
14 September 2005
08 June 2005
10 November 2005
22 April 2005
25 March 2004
29 January 2004
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
29 June 2020
Date of mailing of the international search report:
09 July 2020
Authorized officer:
Pérez-Mato, Isabel
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