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1. WO2020118198 - SYSTÈMES DE CRIBLAGE D'INTERACTIONS PROTÉINE-PROTÉINE


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INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/US2019/064969 52652-705601
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
06 December 2019 07 December 2018
Applicant
OCTANT, INC.
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
1. With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
a. forming part of the international application as filed:
in the form of an Annex C/ST.25 text file.
on paper or in the form of an image file.
b. furnished together with the international application under PCT Rule 13ter.1(a) for the purposes of international search only in the form of an Annex C/ST.25 text file.
c. furnished subsequent to the international filing date for the purposes of international search only:
in the form of an Annex C/ST.25 text file (Rule 13ter.1(a)).
on paper or in the form of an image file (Rule 13ter.1(b) and Administrative Instructions, Section 713).
2.
In addition, in the case that more than one version or copy of a sequence listing has been filed or furnished, the required statements that the information in the subsequent or additional copies is identical to that forming part of the application as filed or does not go beyond the application as filed, as appropriate, were furnished.
3.
Additional comments:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No.     1A    
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     C12N 15/10 (2006.01)i; C12Q 1/37 (2006.01)i; C40B 30/04 (2006.01)i; G01N 33/50 (2006.01)i; G01N 33/68 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     C12N; G01N; C12Q; C40B
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, BIOSIS, EMBASE, WPI Data

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
X
BOTVINNIK A ET AL, "Integrated analysis of receptor activation and dowstream signaling with EXTassays", Vol. 7, No. 1, 01 January 2009 (2009-01-01), page 74-80, NATURE METHODS, NATURE PUB. GROUP, NEW YORK
Retrieved from the Internet:
URL:http://www.nature.com/nmeth/journal/v7/n1/pdf/nmeth.1407.pdf
XP002566572
[retrieved on  2010-01-28]
1-30
Y
the whole document
31-59
(2)
X
WEHR MICHAEL C ET AL, "Split protein biosensor assays in molecular pharmacological studies", DRUG DISCOVERY TODAY, ELSEVIER, AMSTERDAM, NL,Vol. 21, No. 3, 21 November 2015 (2015-11-21), page 415-429,
XP029464364
1,2,26,29
the whole document
(3)
Y
JULIA PETSCHNIGG ET AL, "Interactive proteomics research technologies: recent applications and advances", 09 September 2010 (2010-09-09), Vol. 22, No. 1, page 50-58,
XP028276921
[retrieved on  2010-09-09]
31-59
the whole document
(4)
Y
EP 1348766 A1 (DUALSYSTEMS BIOTECH AG [CH]) 01 October 2003 (2003-10-01)
31-59
claims 1-47
(5)
Y
THAMINY S ET AL, "Identification of novel ErbB3-interacting factors using the split-ubiquitin membrane yeast two-hybrid system", GENOME RESEARCH, COLD SPRING HARBOR LABORATORY PRESS, US,Vol. 13, No. 7, 01 July 2003 (2003-07-01), page 1744-1753,
XP002288002
31-59
the whole document
(6)
Y
Julia Petschnigg, "The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells", 01 May 2014 (2014-05-01), page 585-592,
Retrieved from the Internet:
URL:http://www.nature.com/nmeth/journal/v11/n5/pdf/nmeth.2895.pdf
XP055301607
[retrieved on  2016-09-12]
31-59
the whole document
(7)
Y
JENNIFER D LEWIS ET AL, "Quantitative Interactor Screening with next-generation Sequencing (QIS-Seq) identifies Arabidopsis thaliana MLO2 as a target of the Pseudomonas syringae type III effector HopZ2", BMC GENOMICS, BIOMED CENTRAL,Vol. 13, No. 1, 09 January 2012 (2012-01-09), page 8,
XP021123450
31-59
the whole document
(8)
A
EP 1483576 A2 (AXARON BIOSCIENCE AG [DE]) 08 December 2004 (2004-12-08)
1-30
claims 1-14
(9)
A
US 2004043388 A1 (COME JON H [US] ET AL) 04 March 2004 (2004-03-04)
1-59
paragraph [0014] - paragraph [0465]
(10)
A
SUJAN S SHEKHAWAT ET AL, "Split-protein systems: beyond binary protein-protein interactions", CURRENT OPINION IN CHEMICAL BIOLOGY,Vol. 15, No. 6, 01 December 2011 (2011-12-01), page 789-797,
XP055268066
1-59
the whole document
(11)
A
MICHAEL C WEHR ET AL, "Monitoring regulated protein-protein interactions using split TEV", NATURE METHODS,Vol. 3, No. 12, 29 October 2006 (2006-10-29), page 985-993,
XP055565855
1-30
the whole document
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
EP 1348766 A1
01 October 2003
AT 348190 T
AU 2003219114 A1
CA 2479999 A1
DE 60216721 T2
EP 1348766 A1
EP 1497457 A1
JP 4216733 B2
JP 2005521408 A
US 2005106636 A1
WO 03083136 A1
15 January 2007
13 October 2003
09 October 2003
18 October 2007
01 October 2003
19 January 2005
28 January 2009
21 July 2005
19 May 2005
09 October 2003
EP 1483576 A2
08 December 2004
AT 483971 T
AU 2003215660 A1
DE 10211063 A1
DK 1483576 T3
DK 2110666 T3
EP 1483576 A2
EP 2110666 A1
US 2005084864 A1
US 2009298089 A1
WO 03076932 A2
15 October 2010
22 September 2003
09 October 2003
31 January 2011
08 April 2013
08 December 2004
21 October 2009
21 April 2005
03 December 2009
18 September 2003
US 2004043388 A1
04 March 2004
NONE
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
13 March 2020
Date of mailing of the international search report:
20 March 2020
Authorized officer:
Westphal-Daniel, K
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