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International application No. Applicant's or agent's file reference
PCT/EP2019/071061 S152171WO
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
06 August 2019 25 September 2018
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
The figure of the drawings to be published with the abstract is Figure No.     2    
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
none of the figures is to be published with the abstract.


     A61K 9/20 (2006.01)i; A61K 9/14 (2006.01)i; A61K 9/16 (2006.01)i; A61K 31/7076 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC


Minimum documentation searched (classification system followed by classification symbols):
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data


Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
EP 2140861 A1 (ABBOTT GMBH & CO KG [DE]) 06 January 2010 (2010-01-06)
the whole document
WO 2015114315 A1 (CHORD THERAPEUTICS S A R L [CH]; LUCAS BRIAN RONALD [GB]) 06 August 2015 (2015-08-06)
the whole document
EP 2340018 A2 (ROQUETTE FRERES [FR]) 06 July 2011 (2011-07-06)
the whole document
US 7037900 B2 (SUPERGEN INC [US]) 02 May 2006 (2006-05-02)
the whole document
Special categories of cited documents:
document defining the general state of the art which is not considered to be of particular relevance
document cited by the applicant in the international application
earlier application or patent but published on or after the international filing date
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
document referring to an oral disclosure, use, exhibition or other means
document published prior to the international filing date but later than the priority date claimed
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
document member of the same patent family


Patent document cited in search report Publication date
Patent family member(s) Publication date
EP 2140861 A1
06 January 2010
AU 2009265737 A1
BR PI0914918 A2
CA 2729148 A1
CN 102083420 A
EP 2140861 A1
EP 2303242 A1
ES 2699075 T3
JP 5717628 B2
JP 5976086 B2
JP 2011526592 A
JP 2015063549 A
KR 20110046457 A
RU 2011103085 A
US 2011182891 A1
US 2014200278 A1
WO 2010000740 A1
07 January 2010
20 October 2015
07 January 2010
01 June 2011
06 January 2010
06 April 2011
07 February 2019
13 May 2015
23 August 2016
13 October 2011
09 April 2015
04 May 2011
10 August 2012
28 July 2011
17 July 2014
07 January 2010
WO 2015114315 A1
06 August 2015
AU 2015212613 A1
CA 2937978 A1
CY 1120139 T1
DK 3099307 T3
EA 201691525 A1
EP 3099307 A1
ES 2655291 T3
HR P20180071 T1
HU E036120 T2
JP 6535678 B2
JP 2017504636 A
LT 3099307 T
NO 3099307 T3
PL 3099307 T3
PT 3099307 T
SI 3099307 T1
US 2016339049 A1
WO 2015114315 A1
01 September 2016
06 August 2015
12 December 2018
22 January 2018
30 December 2016
07 December 2016
19 February 2018
23 February 2018
28 June 2018
26 June 2019
09 February 2017
12 February 2018
17 March 2018
30 March 2018
08 January 2018
28 February 2018
24 November 2016
06 August 2015
EP 2340018 A2
06 July 2011
CN 102196806 A
CN 102196807 A
EP 2179727 A1
EP 2340018 A2
EP 2340019 A1
ES 2391876 T3
ES 2415747 T3
ES 2425762 T3
JP 5685542 B2
JP 5697598 B2
JP 2012506849 A
JP 2012506850 A
US 2011200680 A1
US 2011256230 A1
WO 2010049432 A1
WO 2010049433 A2
21 September 2011
21 September 2011
28 April 2010
06 July 2011
06 July 2011
30 November 2012
26 July 2013
17 October 2013
18 March 2015
08 April 2015
22 March 2012
22 March 2012
18 August 2011
20 October 2011
06 May 2010
06 May 2010
US 7037900 B2
02 May 2006
CA 2463105 A1
EP 1443820 A1
US 2003073649 A1
US 2006025359 A1
US 2007066517 A1
WO 03030643 A1
17 April 2003
11 August 2004
17 April 2003
02 February 2006
22 March 2007
17 April 2003
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
25 October 2019
Date of mailing of the international search report:
11 November 2019
Authorized officer:
Giró, Annalisa
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