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1. WO2019214591 - PRODUIT SANGUIN DÉRIVÉ D'UN PORC KNOCK-OUT DE GÈNE ET SON UTILISATION

Numéro de publication WO/2019/214591
Date de publication 14.11.2019
N° de la demande internationale PCT/CN2019/085773
Date du dépôt international 07.05.2019
CIB
A61K 35/12 2015.01
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
35Préparations médicinales contenant des substances ou leurs produits de réaction de constitution non déterminée
12Substances provenant de mammifères; Compositions comprenant des tissus ou des cellules non spécifiés; Compositions comprenant des cellules souches non embryonnaires; Cellules génétiquement modifiées
A01K 67/027 2006.01
ANÉCESSITÉS COURANTES DE LA VIE
01AGRICULTURE; SYLVICULTURE; ÉLEVAGE; CHASSE; PIÉGEAGE; PÊCHE
KÉLEVAGE; AVICULTURE; APICULTURE; PISCICULTURE; PÊCHE; OBTENTION D'ANIMAUX, NON PRÉVUE AILLEURS; NOUVELLES RACES D'ANIMAUX
67Élevage ou obtention d'animaux, non prévus ailleurs; Nouvelles races d'animaux
027Nouvelles races de vertébrés
CPC
C12N 15/66
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
66General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
C12N 15/85
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
85for animal cells
C12N 15/873
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
873Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
C12N 15/907
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
90Stable introduction of foreign DNA into chromosome
902using homologous recombination
907in mammalian cells
C12N 2510/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2510Genetically modified cells
C12N 2800/107
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2800Nucleic acids vectors
10Plasmid DNA
106for vertebrates
107for mammalian
Déposants
  • 创观(苏州)生物科技有限公司 GCREATENE (SUZHOU) BIOTECHNOLOGY CO., LTD. [CN]/[CN]
Inventeurs
  • 戴一凡 DAI, Yifan
  • 杨海元 YANG, Haiyuan
  • 王盈 WANG, Ying
Mandataires
  • 上海巅石知识产权代理事务所(普通合伙) SHANGHAI DIANSHI PARTNERS, P.C.
Données relatives à la priorité
201810426018.607.05.2018CN
Langue de publication chinois (ZH)
Langue de dépôt chinois (ZH)
États désignés
Titre
(EN) BLOOD PRODUCT DERIVED FROM GENE KNOCKOUT PIG AND USE THEREOF
(FR) PRODUIT SANGUIN DÉRIVÉ D'UN PORC KNOCK-OUT DE GÈNE ET SON UTILISATION
(ZH) 源自基因敲除猪的血液产品及其用途
Abrégé
(EN)
Provided are a blood product derived from a gene knockout pig and use of the blood product. The binding of the blood product to immunoglobulin in human serum is reduced, and the blood product has an effect on overcoming hyperacute immune rejection.
(FR)
L'invention concerne un produit sanguin dérivé d'un porc knock-out de gène et l'utilisation du produit sanguin. La liaison du produit sanguin à l'immunoglobuline dans le sérum humain est réduite, et le produit sanguin a pour effet de surmonter le rejet immunitaire hyper-aigu.
(ZH)
提供了一种源自基因敲除猪的血液产品,以及该血液产品的应用。该血液产品与人血清中免疫球蛋白结合降低,对克服超急性免疫排斥反应有作用。
Également publié en tant que
EP2019799696
Dernières données bibliographiques dont dispose le Bureau international