Certains contenus de cette application ne sont pas disponibles pour le moment.
Si cette situation persiste, veuillez nous contacter àObservations et contact
1. (WO2019003105) SURVEILLANCE CONTINUE DE LA PERFUSION D'UN ORGANE OU D'UNE EXTRÉMITÉ
Note: Texte fondé sur des processus automatiques de reconnaissance optique de caractères. Seule la version PDF a une valeur juridique

CLAIMS

What is claimed is:

1. A method for assessing obstruction in a blood vessel comprising:

measuring a delay in wave propagation of a blood perfusion wave, which is associated with flow of blood through a blood vessel, and correlating said delay to an amount of occlusion in the blood vessel, wherein if said delay is greater, the amount of occlusion is greater.

2. The method according to claim 1, wherein said delay in wave propagation is associated with a change in a shape of said perfusion wave.

3. The method according to claim 1, wherein said delay is a peak perfusion delay includes: (a) an interval from an R wave to a perfusion onset, also referred to as pulse-transit time; (b) a relatively slow phase of the perfusion wave and (c) a relatively fast second phase of the perfusion wave up to a peak of the perfusion wave.

4. The method according to claim 1, wherein said delay in wave propagation is associated with a change in a power spectrum of said perfusion wave.

5. The method according to claim 1, further comprising measuring said delay in wave propagation in left and right limbs and comparing the delay in each of the limbs.

6. The method according to claim 1, wherein measuring said delay is done by measuring coherence between different limbs or sites, or between different acquisitions in time.

7. The method according to claim 1, further comprising differentiating between respiratory and cardiac modulations of said perfusion wave, wherein attenuation of a cardiac component of the perfusion wave indicates partial arterial occlusion, whereas attenuation of a respiratory component of the perfusion wave indicates partial venous occlusion.

8. The method according to claim 1, wherein the correlating is done by wavelet coherence analysis, by continuous wavelet transform, or by analysis of a time-frequency domain associated with said delay.

9. The method according to claim 6, wherein differentiating between said respiratory and said cardiac components is done by quantifying changes in a spectrum between different limbs or sites or between different acquisitions in time.

10. A method for assessing obstruction in a blood vessel comprising:

measuring a wave propagation of a blood perfusion wave, which is associated with flow of blood through a blood vessel; and

differentiating between respiratory and cardiac modulations of said perfusion wave, wherein attenuation of a cardiac component of the perfusion wave indicates partial arterial occlusion, and attenuation of a respiratory component of the perfusion wave indicates partial venous occlusion.

11. The method according to claim 10, wherein differentiating between said respiratory and said cardiac components is done by quantifying changes in a spectrum between different limbs or sites or between different acquisitions in time.

12. A system for assessing obstruction in a blood vessel comprising:

a sensor configured to measure a delay in wave propagation of a blood perfusion wave, which is associated with flow of blood through a blood vessel; and a processor configured to correlate said delay to an amount of occlusion in the blood vessel, wherein if said delay is greater, the amount of occlusion is greater.

13. The system according to claim 12, wherein said sensor comprises an electrocardiogram (ECG) sensor.

14. The system according to claim 12, wherein said sensor comprises a photo-plethysmography (PPG) sensor.

15. The system according to claim 12, wherein said sensor comprises an impedance plethysmography (IPG) sensor.

16. The system according to claim 12, wherein said sensor comprises a tonometry sensor.

17. The system according to claim 12, wherein said sensor comprises an accelerometer.