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1. WO2012142318 - DISPOSITIF D'ADMINISTRATION D'UN MÉDICAMENT CONSTITUÉ DE PLUSIEURS PELLICULES MINCES, ET PROCÉDÉS DE FABRICATION ET D'UTILISATION ASSOCIÉS

Numéro de publication WO/2012/142318
Date de publication 18.10.2012
N° de la demande internationale PCT/US2012/033366
Date du dépôt international 12.04.2012
CIB
A61K 9/00 2006.01
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
9Préparations médicinales caractérisées par un aspect particulier
CPC
A61F 9/0017
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
9Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
0008Introducing ophthalmic products into the ocular cavity or retaining products therein
0017implantable in, or in contact with, the eye, e.g. ocular inserts
A61K 31/436
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
4353ortho- or peri-condensed with heterocyclic ring systems
436the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
A61K 47/34
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 47/42
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
A61K 9/0048
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0048Eye, e.g. artificial tears
A61K 9/0051
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0048Eye, e.g. artificial tears
0051Ocular inserts, ocular implants
Déposants
  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US]/[US] (AllExceptUS)
  • DESAI, Tejal A. [US]/[US] (UsOnly)
  • STEEDMAN, Mark Rory [US]/[US] (UsOnly)
  • BHISITKUL, Robert B. [US]/[US] (UsOnly)
  • BERNARDS, Daniel A. [US]/[US] (UsOnly)
  • LANCE, Kevin D. [US]/[US] (UsOnly)
Inventeurs
  • DESAI, Tejal A.
  • STEEDMAN, Mark Rory
  • BHISITKUL, Robert B.
  • BERNARDS, Daniel A.
  • LANCE, Kevin D.
Mandataires
  • BABA, Edward J.
Données relatives à la priorité
61/475,37314.04.2011US
Langue de publication anglais (EN)
Langue de dépôt anglais (EN)
États désignés
Titre
(EN) MULTILAYER THIN FILM DRUG DELIVERY DEVICE AND METHODS OF MAKING AND USING THE SAME
(FR) DISPOSITIF D'ADMINISTRATION D'UN MÉDICAMENT CONSTITUÉ DE PLUSIEURS PELLICULES MINCES, ET PROCÉDÉS DE FABRICATION ET D'UTILISATION ASSOCIÉS
Abrégé
(EN)
Multilayer thin film devices that include a bioactive agent for elution to the surrounding tissue upon administration to a subject are provided. The multilayer thin film devices are useful as medical devices, such as ocular devices. Also provided are methods and kits for localized delivery of a bioactive agent to a tissue of a subject, and methods of preparing the subject devices. The multilayer thin film medical device includes a first layer, a bioactive agent and a second layer. The first and the second layers may be porous or non-porous. The devices have a furled structure, suitable for administration to a subject.
(FR)
Cette invention concerne des dispositifs constitués de plusieurs pellicules minces comprenant un agent bioactif soumis à une élution dans le tissu avoisinant après administration. Ces dispositifs sont utilisés dans le domaine médical, par exemple, comme dispositifs oculaires. L'invention concerne également des procédés et des kits permettant d'administrer localement un agent bioactif à un tissu chez un sujet, et des procédés de préparation desdits dispositifs. Le dispositif constitué de plusieurs pellicules minces comporte une première couche, un agent bioactif et une seconde couche. La première couche et la seconde couche peuvent être poreuses ou non. La structure des dispositifs est repliée et convient pour une administration chez un sujet.
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