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1. WO2012001103 - PEPTIDES CITRULLINÉS D'HISTONE ET LEURS UTILISATIONS

Numéro de publication WO/2012/001103
Date de publication 05.01.2012
N° de la demande internationale PCT/EP2011/061006
Date du dépôt international 30.06.2011
CIB
C07K 14/47 2006.01
CCHIMIE; MÉTALLURGIE
07CHIMIE ORGANIQUE
KPEPTIDES
14Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés
435provenant d'animaux; provenant d'humains
46provenant de vertébrés
47provenant de mammifères
G01N 33/68 2006.01
GPHYSIQUE
01MÉTROLOGIE; TESTS
NRECHERCHE OU ANALYSE DES MATÉRIAUX PAR DÉTERMINATION DE LEURS PROPRIÉTÉS CHIMIQUES OU PHYSIQUES
33Recherche ou analyse des matériaux par des méthodes spécifiques non couvertes par les groupes G01N1/-G01N31/146
48Matériau biologique, p.ex. sang, urine; Hémocytomètres
50Analyse chimique de matériau biologique, p.ex. de sang ou d'urine; Test par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligands; Test immunologique
68faisant intervenir des protéines, peptides ou amino-acides
C07K 16/18 2006.01
CCHIMIE; MÉTALLURGIE
07CHIMIE ORGANIQUE
KPEPTIDES
16Immunoglobulines, p.ex. anticorps monoclonaux ou polyclonaux
18contre du matériel provenant d'animaux ou d'humains
CPC
C07K 14/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
C07K 14/47
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
G01N 2800/24
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
24Immunology or allergic disorders
G01N 33/564
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
564for pre-existing immune complex or autoimmune disease ; , i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
G01N 33/6875
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
6875Nucleoproteins
G01N 33/6893
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
6893related to diseases not provided for elsewhere
Déposants
  • TOSCANA BIOMARKERS S.R.L. [IT/IT]; Via Fiorentina, 1 I-53100 Siena, IT (AllExceptUS)
  • PRATESI, Federico [IT/IT]; IT (UsOnly)
  • ALCARO, Maria Claudia [IT/IT]; IT (UsOnly)
  • CHELLI, Mario [IT/IT]; IT (UsOnly)
  • LOLLI, Francesco [IT/IT]; IT (UsOnly)
  • PAOLINI, Ilaria [IT/IT]; IT (UsOnly)
  • PAPINI, Anna Maria [IT/IT]; IT (UsOnly)
  • ROVERO, Paolo [IT/IT]; IT (UsOnly)
  • MIGLIORINI, Paola [IT/IT]; IT (UsOnly)
Inventeurs
  • PRATESI, Federico; IT
  • ALCARO, Maria Claudia; IT
  • CHELLI, Mario; IT
  • LOLLI, Francesco; IT
  • PAOLINI, Ilaria; IT
  • PAPINI, Anna Maria; IT
  • ROVERO, Paolo; IT
  • MIGLIORINI, Paola; IT
Mandataires
  • CAPASSO, Olga; c/o De Simone and Partners S.p.A Via Vincenzo Bellini, 20 I-00198 Rome, IT
Données relatives à la priorité
10168270.602.07.2010EP
Langue de publication anglais (EN)
Langue de dépôt anglais (EN)
États désignés
Titre
(EN) HISTONE CITRULLINATED PEPTIDES AND USES THEREOF
(FR) PEPTIDES CITRULLINÉS D'HISTONE ET LEURS UTILISATIONS
Abrégé
(EN)
The present invention refers to citrullinated synthetic peptides derived from the histone H4 protein and their use in the diagnosis of autoimmune diseases,particularly Rheumatoid Arthritis (RA).
(FR)
La présente invention concerne des peptides synthétiques citrullinés dérivés de la protéine histone H4 et leur utilisation pour le diagnostic de maladies auto-immunes, notamment la polyarthrite rhumatoïde (PR).
Dernières données bibliographiques dont dispose le Bureau international