Traitement en cours

Veuillez attendre...

Paramétrages

Paramétrages

Aller à Demande

1. WO2008012785 - SONDE D'OXYGÈNE CELLULAIRE

Numéro de publication WO/2008/012785
Date de publication 31.01.2008
N° de la demande internationale PCT/IE2007/000071
Date du dépôt international 24.07.2007
CIB
A61K 49/00 2006.01
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
49Préparations pour examen in vivo
CPC
A61K 49/0015
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
001Preparation for luminescence or biological staining
0013Luminescence
0015Phosphorescence
A61K 49/0019
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
001Preparation for luminescence or biological staining
0013Luminescence
0017Fluorescence in vivo
0019characterised by the fluorescent group
A61K 49/0036
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
001Preparation for luminescence or biological staining
0013Luminescence
0017Fluorescence in vivo
0019characterised by the fluorescent group
0021the fluorescent group being a small organic molecule
0036Porphyrins
A61K 49/0056
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
001Preparation for luminescence or biological staining
0013Luminescence
0017Fluorescence in vivo
005characterised by the carrier molecule carrying the fluorescent agent
0056Peptides, proteins, polyamino acids
C12M 41/38
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
41Means for regulation, monitoring, measurement or control, e.g. flow regulation
30of concentration
38of metabolites or enzymes in the cells
G01N 21/6428
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
Déposants
  • UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK [IE]/[IE] (AllExceptUS)
  • PAPKOVSKY, Dimitri [IE]/[IE] (UsOnly)
  • O'RIORDAN, Tomas [IE]/[IE] (UsOnly)
  • PONOMAREV, Gelii, V. [RU]/[RU] (UsOnly)
Inventeurs
  • PAPKOVSKY, Dimitri
  • O'RIORDAN, Tomas
  • PONOMAREV, Gelii, V.
Mandataires
  • O'BRIEN, John, A.
Données relatives à la priorité
2006/054424.07.2006IE
Langue de publication anglais (EN)
Langue de dépôt anglais (EN)
États désignés
Titre
(EN) A PROBE FOR CELLULAR OXYGEN
(FR) SONDE D'OXYGÈNE CELLULAIRE
Abrégé
(EN)
A probe for sensing and imaging intracellular oxygen comprises an oxygen-sensitive fluorescent or phosphorescent dye combined with a hydrophilic macromolecular carrier and a cell loading agent. A method for sensing cellular oxygen using the probe is also described.
(FR)
L'invention porte sur une sonde destinée à détecter l'oxygène cellulaire et à en former une image, sonde qui comprend un colorant fluorescent ou phosphorescent sensible à l'oxygène combiné à un véhicule macromoléculaire hydrophile et à un agent de chargement cellulaire. L'invention concerne également un procédé qui permet de détecter l'oxygène cellulaire au moyen de la sonde précitée.
Également publié en tant que
Dernières données bibliographiques dont dispose le Bureau international