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1. (WO2005009480) TRAITEMENT DE TROUBLES DE L'APPAREIL GENITO-URINAIRE
Dernières données bibliographiques dont dispose le Bureau international   

N° de publication :    WO/2005/009480    N° de la demande internationale :    PCT/US2004/018455
Date de publication : 03.02.2005 Date de dépôt international : 09.06.2004
CIB :
A61K 47/48 (2006.01), A61K 51/12 (2006.01)
Déposants : CONTROL DELIVERY SYSTEMS, INC. [US/US]; 400 Pleasant Street, Watertown, MA 02472 (US) (Tous Sauf US).
ASHTON, Paul [GB/US]; (US) (US Seulement).
CYNKOWSKA, Grazyna [US/US]; (US) (US Seulement).
CYNKOWSKI, Tadeusz [US/US]; (US) (US Seulement).
SMITH, Thomas, J. [CA/US]; (US) (US Seulement)
Inventeurs : ASHTON, Paul; (US).
CYNKOWSKA, Grazyna; (US).
CYNKOWSKI, Tadeusz; (US).
SMITH, Thomas, J.; (US)
Mandataire : HALSTEAD, David, P.; Ropes & Gray, LLP., One International Place, Boston, MA 02110-2624 (US)
Données relatives à la priorité :
60/477,526 11.06.2003 US
60/479,023 16.06.2003 US
Titre (EN) IMPLANTS CONTAINING CODRUGS
(FR) TRAITEMENT DE TROUBLES DE L'APPAREIL GENITO-URINAIRE
Abrégé : front page image
(EN)Genitourinary system disorders are treated with therapeutic agents, and optionally further with radiation treatments. One aspect of the invention provides a drug delivery device comprising a codrug or a pharmaceutically acceptable salt or prodrug thereof, for administration of at least one biologically active moiety, which codrug comprises: a) at least two constituent moieties, each moiety being a residue of a biologically active compound or a product thereof, including a first constituent moiety and a second constituent moiety; and b) a linkage covalently linking said at least two constituent moieties to form said codrug, said linkage is cleaved under physiological conditions to regenerate said constituent moieties; wherein the device is dimensioned to position two radiation seeds a predetermined distance apart. Another aspect of the invention provides a drug delivery device comprising a codrug or a pharmaceutically acceptable salt or prodrug thereof, for administration of at least one biologically active moiety, which codrug comprises: a) at least two constituent moieties, each moiety being a residue of a biologically active compound or a product thereof, including a first constituent moiety and a second constituent moiety; and b) a linkage covalently linking said at least two constituent moieties to form said codrug, said linkage is cleaved under physiological conditions to regenerate said constituent moieties.
(FR)Selon l'invention, les troubles de l'appareil génito-uninaire sont traités à l'aide d'agents thérapeutiques, puis éventuellement par le biais de radiothérapies.
États désignés : AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW.
Organisation régionale africaine de la propriété intellectuelle (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Office eurasien des brevets (OEAB) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
Office européen des brevets (OEB) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IT, LU, MC, NL, PL, PT, RO, SE, SI, SK, TR)
Organisation africaine de la propriété intellectuelle (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Langue de publication : anglais (EN)
Langue de dépôt : anglais (EN)