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Paramétrages

1. WO2005007850 - PROCEDE D'INFUSION D'UN ARN DANS UNE CELLULE

Numéro de publication WO/2005/007850
Date de publication 27.01.2005
N° de la demande internationale PCT/JP2004/010548
Date du dépôt international 16.07.2004
Demande présentée en vertu du Chapitre 2 21.01.2005
CIB
C12N 15/11 2006.01
CCHIMIE; MÉTALLURGIE
12BIOCHIMIE; BIÈRE; SPIRITUEUX; VIN; VINAIGRE; MICROBIOLOGIE; ENZYMOLOGIE; TECHNIQUES DE MUTATION OU DE GÉNÉTIQUE
NMICRO-ORGANISMES OU ENZYMES; COMPOSITIONS LES CONTENANT; CULTURE OU CONSERVATION DE MICRO-ORGANISMES; TECHNIQUES DE MUTATION OU DE GÉNÉTIQUE; MILIEUX DE CULTURE
15Techniques de mutation ou génie génétique; ADN ou ARN concernant le génie génétique, vecteurs, p.ex. plasmides, ou leur isolement, leur préparation ou leur purification; Utilisation d'hôtes pour ceux-ci
09Technologie d'ADN recombinant
11Fragments d'ADN ou d'ARN; Leurs formes modifiées
CPC
A61K 47/6951
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
50the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
69the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
6949inclusion complexes, e.g. clathrates, cavitates or fullerenes
6951using cyclodextrin
B82Y 5/00
BPERFORMING OPERATIONS; TRANSPORTING
82NANOTECHNOLOGY
YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
5Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
C12N 15/111
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
111General methods applicable to biologically active non-coding nucleic acids
C12N 15/87
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
C12N 2310/14
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2310Structure or type of the nucleic acid
10Type of nucleic acid
14interfering N.A.
C12N 2320/32
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2320Applications; Uses
30Special therapeutic applications
32Special delivery means, e.g. tissue-specific
Déposants
  • 財団法人くまもとテクノ産業財団 KUMAMOTO TECHNOLOGY & INDUSTRY FOUNDATION [JP/JP]; 〒8612202 熊本県上益城郡益城町大字田原2081番地10 Kumamoto 2081-10, Oaza Tabaru, Mashiki-machi, Kamimashiki-gun, Kumamoto 8612202, JP (AllExceptUS)
  • 有馬 英俊 ARIMA, Hidetoshi [JP/JP]; JP (UsOnly)
  • 平山 文俊 HIRAYAMA, Fumitoshi [JP/JP]; JP (UsOnly)
  • 上釜 兼人 UEKAMA, Kaneto [JP/JP]; JP (UsOnly)
Inventeurs
  • 有馬 英俊 ARIMA, Hidetoshi; JP
  • 平山 文俊 HIRAYAMA, Fumitoshi; JP
  • 上釜 兼人 UEKAMA, Kaneto; JP
Mandataires
  • 特許業務法人特許事務所サイクス SIKs & Co.; 〒1040031 東京都中央区京橋一丁目8番7号 京橋日殖ビル8階 Tokyo Kyobashi-Nisshoku Bldg., 8th Floor 8-7, Kyobashi 1-come, Chuo-ku, Tokyo 104-0031, JP
Données relatives à la priorité
2003-19777316.07.2003JP
Langue de publication japonais (JA)
Langue de dépôt japonais (JA)
États désignés
Titre
(EN) METHOD OF INFUSING RNA IN CELL
(FR) PROCEDE D'INFUSION D'UN ARN DANS UNE CELLULE
(JA) 細胞にRNAを導入する方法
Abrégé
(EN)
A method of efficiently infusing RNA, especially siRNA, in cells. There is provided a method of infusing RNA in cells which comprises the step of incubating cells in the presence of RNA to be infused and a cyclodextrin/ dendrimer composite.
(FR)
L'invention concerne un procédé permettant d'infuser de manière efficace un ARN, notamment l'ARNsi dans des cellules, et comprenant l'étape consistant à incuber des cellules en présence de l'ARN à infuser et d'un composite de cyclodextrine/dendrimère.
(JA)
 本発明の目的は、RNA、特にsiRNAを細胞内に効率よく導入する方法を提供することである。本発明によれば、導入すべきRNAとシクロデキストリン・デンドリマー結合体の存在下で細胞をインキュベーションする工程を含む、細胞にRNAを導入する方法が提供される。
Également publié en tant que
Dernières données bibliographiques dont dispose le Bureau international