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1. WO2005000266 - FORMULATIONS LIPOSOMALES COMBINEES

Numéro de publication WO/2005/000266
Date de publication 06.01.2005
N° de la demande internationale PCT/US2004/016413
Date du dépôt international 22.05.2004
CIB
A61K 9/127 2006.01
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
9Préparations médicinales caractérisées par un aspect particulier
10Dispersions; Emulsions
127Liposomes
CPC
A61K 48/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A61K 9/127
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
A61P 17/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
C12N 15/88
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
88using microencapsulation, e.g. using ; amphiphile; liposome vesicle
Y02A 50/463
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
50in human health protection
30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
46Medical treatment of waterborne diseases characterized by the agent
462The waterborne disease being caused by a virus
463the virus being the Hepatitis A virus [HAV]
Déposants
  • NEOPHARM, INC. [US/US]; 150 Field Drive, Suite 195 Lake Forest, IL 60045, US (AllExceptUS)
  • JAMIL, Haris [US/US]; US (UsOnly)
  • AHMAD, Imran [US/US]; US (UsOnly)
  • AHMAD, Zafeer [US/US]; US (UsOnly)
  • ANYARAMBHATLA, Gopal [IN/US]; US (UsOnly)
Inventeurs
  • JAMIL, Haris; US
  • AHMAD, Imran; US
  • AHMAD, Zafeer; US
  • ANYARAMBHATLA, Gopal; US
Mandataires
  • HEFNER, Daniel, M. ; Leydig, Voit & Mayer, Ltd. Two Prudential Plaza, Suite 4900 180 N. Stetson Avenue Chicago, IL 60601-6780, US
Données relatives à la priorité
60/472,66422.05.2003US
60/495,26013.08.2003US
Langue de publication anglais (EN)
Langue de dépôt anglais (EN)
États désignés
Titre
(EN) LIPOSOMAL FORMULATIONS COMPRISING A COMBINATION OF TWO OR MORE ACTIVE AGENTS
(FR) FORMULATIONS LIPOSOMALES COMBINEES
Abrégé
(EN)
The present invention provides a composition comprising a physiologically acceptable carrier and two or more agents encapsulated in a liposome, wherein the combination of the two or more agents possess the following properties: (1) cytotoxicity to tumor cells, (2) nutritional properties, (3) use in application to nails, hair, skin or lips or (4) activity against parasites and insects. The invention also provides a method of making such a composition. The invention further provides the use of said composition for a manufacture of a medicament for treating cancer when the combination of the two or more agents is cytotoxic to tumor cells.
(FR)
L'invention concerne une composition comprenant un excipient pharmaceutiquement acceptable et au moins deux agents encapsulés dans un liposome. La combinaison de ces deux agents possède les propriétés suivantes: (1) cytotoxicité sur les cellules tumorales, (2) propriétés nutritives, (3) utilisation pour les ongles, les cheveux, la peau ou les lèvres, ou (4) effet contre les parasites et les insectes. L'invention concerne également un procédé de production desdites compositions. Elle concerne en outre un procédé de traitement du cancer qui exploite l'effet cytotoxique de la combinaison des deux agents sur les cellules tumorales.
Également publié en tant que
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