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1. WO2004098310 - PEPTIDES AYANT UN EFFET INHIBITEUR SUR L'ENZYME ACE

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Claims

1. Use of the pentapeptide IIAEK, the pentapeptide IPAVF and/or the hexapeptide IPAVFK and salts thereof for the preparation of an angiotensin-converting enzyme
inhibitor.

2. Use according to claim 1, wherein the angiotensin- converting enzyme inhibitor is a functional food product .

3. Use according to claim 1 or 2, wherein the peptide is
IPAVFK and is used for the preparation of an
antibactericidal product.

4. Use according to any of claims 1-3, wherein the peptide is IIAEK and is used for the preparation of a
hypercholesterolimic product.

5. Food product suitable for angiotensin-converting enzyme inhibition comprising an amount of 25mg/g or more of
IIAEK and/or 5mg/g or more of pentapeptide IPAVF and/or 3mg/g or more of the hexapeptide IPAVFK.

6. Food product according to claim 5, wherein the amount of IIAEK is 50mg/g or more and/or the amount of pentapeptide IPAVF is lOmg/g or more and/or the amount of hexapeptide IPAVFK is 6mg/g or more.

7. Process for the preparation of a food product according to claim 5 or 6, involving the following steps: a) enzymatic hydrolysis of a whey protein substrate
comprising beta-lactoglobulin resulting in a
hydrolysed whey product;
b) separation from the hydrolysed whey product of a
fraction rich in pentapeptide IIAEK, the
pentapeptide IPAVF and/or the hexapeptide IPAVFK; c) drying the fraction from step b) to obtain a solid
rich in pentapeptide IIAEK, the pentapeptide IPAVF
and/or the hexapeptide IPAVFK;
d) using the solid prepared in step c) as an ingredient in the preparation of the food product.

8. Process according to claim 7, wherein the enzymatic hydrolysis is performed using trypsin as enzyme.

9. Process according to claim 8, wherein a mixture of trypsin and chymotrypsin is used as enzyme.