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1. WO2004094586 - SUBSTRAT DE CROISSANCE CELLULAIRE SOUPLE TRIDIMENSIONNEL ET PROCEDES ASSOCIES

Numéro de publication WO/2004/094586
Date de publication 04.11.2004
N° de la demande internationale PCT/US2004/011796
Date du dépôt international 16.04.2004
Demande présentée en vertu du Chapitre 2 27.09.2004
CIB
C12N 5/00 2006.01
CCHIMIE; MÉTALLURGIE
12BIOCHIMIE; BIÈRE; SPIRITUEUX; VIN; VINAIGRE; MICROBIOLOGIE; ENZYMOLOGIE; TECHNIQUES DE MUTATION OU DE GÉNÉTIQUE
NMICRO-ORGANISMES OU ENZYMES; COMPOSITIONS LES CONTENANT; CULTURE OU CONSERVATION DE MICRO-ORGANISMES; TECHNIQUES DE MUTATION OU DE GÉNÉTIQUE; MILIEUX DE CULTURE
5Cellules non différenciées humaines, animales ou végétales, p.ex. lignées cellulaires; Tissus; Leur culture ou conservation; Milieux de culture à cet effet
CPC
C12M 23/20
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
23Constructional details, e.g. recesses, hinges
20Material Coatings
C12M 25/02
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
25Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
02Membranes; Filters
C12M 25/14
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
25Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
14Scaffolds; Matrices
C12M 35/04
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
35Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
04Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
C12N 2533/30
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2533Supports or coatings for cell culture, characterised by material
30Synthetic polymers
C12N 2533/52
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2533Supports or coatings for cell culture, characterised by material
50Proteins
52Fibronectin; Laminin
Déposants
  • CARNEGIE MELLON UNIVERSITY [US]/[US] (AllExceptUS)
  • LEDUC, Philip, R. [US]/[US] (UsOnly)
  • KUBICEK, James, D. [US]/[US] (UsOnly)
  • BRELSFORD, Stephanie [US]/[US] (UsOnly)
Inventeurs
  • LEDUC, Philip, R.
  • KUBICEK, James, D.
  • BRELSFORD, Stephanie
Mandataires
  • HIRSHMAN, Jesse, A.
Données relatives à la priorité
60/464,01018.04.2003US
Langue de publication anglais (EN)
Langue de dépôt anglais (EN)
États désignés
Titre
(EN) THREE-DIMENTIONAL, FLEXIBLE CELL GROWTH SUBSTRATE AND RELATED METHODS
(FR) SUBSTRAT DE CROISSANCE CELLULAIRE SOUPLE TRIDIMENSIONNEL ET PROCEDES ASSOCIES
Abrégé
(EN)
An engineered cell growth substrate is provided along with an apparatus containing the substrate. The substrate contains features, including, without limitation: an extracellular matrix mimetic, areas of differing elasticity moduli and/or 3-dimensional engineered formations, such as grooves or protuberances. Methods of fabricating the cell growth substrate, methods of growing cells on the substrate, and methods of evaluating analytes on cells on the substrate also are provided.
(FR)
L'invention concerne un substrat de croissance cellulaire technique et un appareil contenant ledit substrat. Ce dernier renferme des caractéristiques, y compris, notamment, une matrice-mimétique extracellulaire, des zones de modules d'élasticité différents et/ou des formations techniques tridimensionnelles, par exemple des rainures ou des protubérances. L'invention concerne enfin des procédés de fabrication du substrat de croissance cellulaire, des procédés de croissance des cellules sur le substrat, et des procédés d'évaluation des analytes des cellules sur le substrat.
Également publié en tant que
US2006270023
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