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1. WO2004093673 - DETECTION OPTIQUE DE CARIES DENTAIRES

Note: Texte fondé sur des processus automatiques de reconnaissance optique de caractères. Seule la version PDF a une valeur juridique

[ EN ]

WHAT IS CLAIMED IS:

1. A method for enhancing imaging of diseased tissue comprising the steps of: (a) quantifying fluorescence spectral values of a plurality of tissue regions of a target tissue, wherein the plurality of tissue regions represents stages of development of a disease;
(b) transforming the fluorescence spectral values to produce enhanced spectral values for each tissue region; and
(c) displaying an enhanced image of the plurality of tissue regions using the transformed spectral values.
2. The method of claim 1, wherein said transforming step (b) includes multiplying the spectral values with predetermined enhancing coefficients to produce the enhanced spectral values, the enhancing coefficients calculated based on spectral changes during the stages of development of the disease.
3. The method of claim 2, wherein the step of quantifying (a) includes measuring fluorescence intensity of each tissue region at a range of wavelengths representing a red spectrum (R), a green spectrum (G) and a blue spectrum (B).
4. The method of claim 3 wherein said step of quantifying (a) further comprises the step of recording the fluorescence spectral values using a digital camera having sensors corresponding to R, G, and B, and producing a digital image having a plurality of pixels,
wherein the fluorescence spectral value recorded by the sensor corresponding to R is represented by a red component (Rm), the fluorescence spectral value recorded by the sensor corresponding to G is represented by a green component (Gm), and the fluorescence spectral value recorded by the sensor corresponding to B is represented by a blue component (Bm) of each pixel.
5. The method of claim 4, wherein said transforming step (b) includes modifying at least one of: Rm, Gm, and Bm of at least one of the plurality of tissue regions to produce the enhanced spectral values for each tissue region.
6. The method of claim 5, wherein said displaying (c) includes displaying the enhanced image of the plurality of tissue regions by digital imaging using Rd, Gd, and Bd of each pixel for each tissue region.

7. The method of claim 2 wherein the plurality of tissue regions comprises : a region of healthy tissue, a region of initial diseased tissue, and a region of advanced diseased tissue.
8. The method of claim 7, wherein the target tissue is a tooth.
9. The method of claim 8, wherein the region of healthy tissue shows no caries (NC), the region of initial diseased tissue shows initial caries (IC), and the region of advanced diseased tissue shows advanced caries (AC).
10. The method of claim 9, wherein the fluorescence spectral values are obtained from measuring fluorescence intensity of NC, IC and AC at a range of wavelengths representing a red spectrum (R), a green spectrum (G) and a blue spectrum (B),
wherein said step of quantifying (a) further comprises the step of recording the fluorescence spectral values of NC, IC, and AC using a digital camera having sensors corresponding to R, G, and B, producing a digital image having a plurality of pixels.

11. The method of claim 10 wherein said fransforming step (b) includes optionally modifying Rm to produce an enhanced red component (Rd), optionally modifying Gm to produce an enhanced green component (Gd), and optionally modifying Bm to produce an enhanced blue component (Bd) of each pixel for corresponding NC, IC and AC.
12. The method of claim 11 wherein the enhanced spectral value, Rd of NC is substantially lower than the enhanced spectral value, R of AC, the enhanced spectral value, Gd of NC is substantially higher than the enhanced spectral value, Gd of AC, and the enhanced spectral value, Bd of NC is optionally substantially higher than the enhanced spectral value, B of NC.
13. The method of claim 12, wherein R of NC is equal to zero (0), and Gd of AC and Bd of AC are equal to zero (0).
14. The method of claim 11 , wherein
Rd of each NC, IC, and AC represents a first linear relationship of Rm, Gm, and Bm of corresponding NC, IC, and AC, respectively,
G of each NC, IC, and AC represents a second linear relationship of Rm, Gm, and Bm of corresponding NC, IC, and AC, respectively, and
Bd of each NC, IC, and AC represents a third linear relationship of Rm, Gm, and Bm of corresponding NC, IC, and AC, respectively.
15. The method of claim 14, wherein the first linear relationship is represented by:

wherein the second linear relationship is represented by:
Gd = bιRm + b2Gm + b3B_m,
wherein the third linear relationship is represented by:
Bd = CiRm + C2Gm + c3Bm,
wherein Rd represents Rd of NC, IC, or AC; Gd represents Gd of NC, IC, or AC; B represents B of NC, IC, or AC; Rm represents Rm of corresponding NC, IC, or AC; Gm represents Gm of corresponding NC, IC, or AC; Bm represents B_m of corresponding NC, IC, or AC; ai, a2, a3, bi, b2, b3, cls c2, and c3 represent predetermined coefficients at each pixel.
16. The method of claim 15 wherein said step of displaying (c) includes producing digital imaging of the enhanced image of NC, IC, and AC by using corresponding Rd, Gd, and Bd.
17. The method of claim 14, wherein R is represented by:
Rd = kπ + k12 d,
Gd = k2ι + k22 d
Bd = 3ι -l- k32 d1
wherein Rd represents R of NC, IC, or AC; Gd represents Gd of NC, IC, or AC; Bd represents B of NC, IC, or AC; d represents the ratio: Rm/(Gm+B_m), wherein Rm represents Rm of corresponding NC, IC, or AC; Gm represents Gm of
corresponding NC, IC, or AC, and Bm of corresponding NC, IC, or AC; kπ, kι2, k2ι, k22, si, k32 represent previously determined coefficients.
18. The method of claim 17 wherein said step of displaying (c) includes producing digital imaging of the enhanced image of NC, IC, and AC by using corresponding Rj, Gd, and Bd.
19. A system for detecting development stages of a disease comprising:
a recording device capable of recording an image of a target tissue having a plurality of regions representing stages of development of a disease, said recording device recording fluorescence spectral values from the plurality of regions;
a processor operably coupled with said recording device for processing the recorded fluorescence spectral values and producing spectral data representing to the plurality of regions of the target tissue;

software operably coupled with said processor for enabling a transformation of spectral data into enhanced spectral data representing an enhanced image of the plurality of regions of the target tissue, the transformation including multiplying the spectral data with predetermined enhancing coefficients, the predetermined enhancing coefficients calculated based on spectral changes during stages of disease
development; and
a display screen operably coupled with software for displaying the enhanced image of the plurality of regions of the target tissue, wherein the plurality of regions are distinguishable by color.
20. The system of claim 19 further comprising a camera probe electronically connected with the recording device, configured to enter restricted area to record the image of the target tissue.
21. The system of claim 19 further comprising a light source for inducing the target tissue to produce fluorescence spectral values.
22. The system of claim 19, wherein said recording device is a digital camera.

23. The system of claim 19, wherein said recording device is a video camera.

24. The system of claim 22 wherein said recording device has a spectral sensors for recording fluorescence spectral values corresponding to the wavelengths representing a plurality of spectra.
25. The system of claim 24, wherein said sensors comprise:
a sensor for recording fluorescence values representing a red spectrum;
a sensor for recording fluorescence values representing a green spectrum; and a sensor for recording fluorescence values representing a blue spectrum.

26. The system of claim 19 wherein said software is provided in a computer defining said display screen.
27. The system of claim 26 wherein said display screen is configured to display a plurality of colors corresponding to the enhanced spectral data.
28. The system of claim 27 wherein said display screen is configured to digitally display the enhanced image.
29. The system of claim 19 adapted to detect a tooth disease.
30. The system of claim 29 adapted to detect tooth caries.