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1. (WO1999034825) VACCIN ANTI-FECONDITE ET MODE D'UTILISATION
Note: Texte fondé sur des processus automatiques de reconnaissance optique de caractères. Seule la version PDF a une valeur juridique

WHAT IS CLAIMED IS:

1. A fertility impairing vaccine comprising an antigen comprising
substantially pure, nonrecombinant zona pellucida glycoprotein, or an antigenic fragment thereof.

2. The fertility impairing vaccine of claim 1 wherein the zona pellucida glycoprotein is porcine zona pellucida glycoprotein.

3. The fertility impairing vaccine of any preceding claim further comprising an immunological adjuvant.

4. The fertility impairing vaccine of claim 3 wherein the immunological adjuvant comprises synthetic trehalose dicorynomycolate.

5. The fertility impairing vaccine of any preceding claim wherein the
vaccine further comprises squalene oil.

6. The fertility impairing vaccine of any preceding claim which is an
immunosterilant vaccine.

7. A method for impairing the fertility of an animal comprising
administering to the animal the vaccine of any of the preceding claims wherein the vaccine is administered in a manner and an amount effective to cause fertility impairment in the animal.

8. The method of claim 7 wherein the vaccine causes temporary, reversible infertility in the animal.

9. The method of claim 7 wherein the vaccine causes permanent,
irreversible infertility in the animal.

10. The method of claims 7, 8 or 9 wherein the animal is a carnivore.

11. The method of claim 10 wherein the carnivore is a dog or a cat.

12. The method of claim 11 wherein the carnivore is a dog.

13. The method of claim 12 wherein administration of the vaccine does not cause abnormal estrus cycles in the dog.

AMENDED CLAIMS
[received by the International Bureau on 14 June 1999 . ( 14.06.99 ) ; original claim 10 cancel led; original claims 1 and 7-9 amended ;' cl aims 1 1 -13 renumbered as claims 10-12 amended ;
remaining claims unchanged (2 pages) ]

1. A fertility impairing vaccine for use in carnivores comprising an antigen comprising substantially pure, nonrecombinant zona pellucida
glycoprotein or an antigenic fragment thereof.

2. The fertility impairing vaccine of claim 1 wherein the zona pellucida glycoprotein is porcine zona pellucida glycoprotein.

3. The fertility impairing vaccine of any preceding claim further comprising an immunological adjuvant.

4. The fertility impairing vaccine of claim 3 wherein the immunological adjuvant comprises synthetic trehalose dicorynomycolate.

5. The fertility impairing vaccine of any preceding claim wherein the
vaccine further comprises squalene oil.

6. The fertility impairing vaccine of any preceding claim which is an
immunosterilant vaccine.

7. A method for impairing the fertility of a carnivore comprising
administering to the carnivore the vaccine of any preceding claim,
wherein the vaccine is administered in a manner and an amount effective to cause fertility impairment in the carnivore.

8. The method of claim 7 wherein the vaccine causes temporary, reversible infertility in the carnivore.

9. The method of claim 7 wherein the vaccine causes permanent,
irreversible infertility in the carnivore.

10. The method of claims 7, 8, or 9 wherein the carnivore is a dog or a cat.

1 1. The method of claim 10 wherein the carnivore is a dog.

12. The method of claim 1 1 wherein administration of the vaccine does not cause abnormal estrus cycles in the dog.