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Paramétrages

Paramétrages

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1. WO1999004237 - 'PRIONINES', MARQUEURS TRES SPECIFIQUES DESTINES A LA DETECTION PRESYMPTOMATIQUE ET NON VULNERANTE DES ENCEPHALOPATHIES SPONGIFORMES TRANSMISSIBLES, ET CIBLES POUR REACTIFS THERAPEUTIQUES DESTINES A PREVENIR CES ENCEPHALOPATHIES ET A LUTTER CONTRE CELLES-CI, CHEZ L'HOMME ET L'ANIMAL

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[ EN ]
What is claimed is:

1. Any method for diagnosis or pre-symptomatic diagnosis of a TSE disease in humans and animals that involves detecting the sequence, a part of the sequence or a modified form of the sequence of any of the proteins having the sequence of the group of proteins BSAS, SCRAPAS and CJAS wherein said sequences are sequence SEQ ID NO : 1, SEQ ID NO : 2 and SEQ ID NO : 3 respectively.

2. Any therapeutic method for preventing, treating or stoping a human or animal TSE disease that targets any of the proteins from the group of proteins of claim 1.

3. Any method for pre-symptomatic diagnosis or therapy of a TSE disease in humans and or animals which uses or targets a protein expressed from within an alternate reading frame of a prion protein gene, and which has structural characteristics resembling, totally or partially, the characteristics of the proteins of claim 1.