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1. WO1992016949 - PROCEDE D'AMELIORATION DU RENDEMENT D'ELUTION D'UN GENERATEUR RADIO-ISOTOPIQUE

Note: Texte fondé sur des processus automatiques de reconnaissance optique de caractères. Seule la version PDF a une valeur juridique

[ EN ]

CLAIMS
1. A method of improving the elution yield of a radioisotope generator, comprising a column containing carrier material adapted to adsorb a parent isotope, said column including an inlet opening and an outlet opening, said outlet opening being connected via an eluate conduit to a tapping point, where a liquid eluate containing a daughter radioisotope can be obtained, said inlet opening being connected via an eluent conduit to an eluent reservoir, said reservoir being provided with an inlet opening for air suppletion to the generator during elution thereof,
said method being characterized, in that during elution of the generator air is supplied to the eluent reservoir, which air has a minimized alcohol content.

2. A method as claimed in claim 1, wherein the column of the radioisotope generator contains a carrier material which at least substantially consists of alumina, wherein the parent isotope is molybdenum-99, wherein the daughter isotope is technetium-99m, and wherein the eluent is a saline solution, preferably a physiological saline solution.

3. A method as claimed in claim 1 or 2, characterized in that during elution of the generator air is supplied to the eluent reservoir, the alcohol content of which is reduced to such an extent, that the alcohol concentration in the eluent never can reach a value of 0.1 cl/ml, preferably of 0.05 μ-1/ml .

4. A method as claimed in claim 3, characterized in that the alcohol content in the air to be supplied to the eluent reservoir is reduced by using a suitable filter means.

5. A method as claimed in claim 4, characterized in that the alcohol content in the air to be supplied to the eluent reservoir is reduced by using an active-carbon filter.

6. A radioisotope generator, comprising a column containing carrier material adapted to adsorb a parent isotope, said column including an inlet opening and an outlet opening, said outlet opening being connected via an eluate conduit to a tapping point, where a liquid eluate containing a daughter radioisotope can be obtained, said inlet opening being connected via an eluent conduit to an eluent reservoir, said reservoir being provided with an inlet opening for air suppletion to the generator during elution thereof, said generator being characterized in that it comprises filter means suitable for reducing the alcohol content of the air to be supplied to the eluent reservoir during elution of the generator.

7. A generator as claimed in claim 6, characterized in that the filter means comprises an active-carbon filter.

8. A generator as claimed in claim 6 or 7, characterized in that the filter means is sealingly connected to the inlet opening of the eluent reservoir.

9. A generator as claimed in claim 8, characterized in that the filter means is connected between the eluent reservoir and a bacteria filter, equally sealingly connected to the inlet opening of the eluent reservoir.