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Machine translation
1. (WO1979000882) MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1979/000882    International Application No.:    PCT/US1979/000202
Publication Date: 01.11.1979 International Filing Date: 02.04.1979
IPC:
G01N 33/542 (2006.01), G01N 33/58 (2006.01)
Applicants:
Inventors:
Priority Data:
893650 05.04.1978 US
Title (EN) MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS
(FR) CONTROLE D"UN MILIEU MACROMOLECULAIRE DANS DES RECEPTEURS D"ESSAI SPECIFIQUES
Abstract: front page image
(EN)Method and compositions are provided for performing protein binding assays involving a homologous pair consisting of ligand and receptor for the ligand. The method employs a label conjugated to a member of said homologous pair and a uniformly dispersed discontinuous phase of discrete particles in a continuous aqueous phase, where the discrete particles create microenvironments which allow for discrimination between the label associated with the particle - in a discontinuous phase - and the label in the continuous phase. Various conjugates and particles are provided which find use in the subject method.
(FR)Methode et compositions pour effectuer des essais de liaison de proteines comprenant une paire homologue consistant en un liant et un recepteur pour le liant. La methode utilise une etiquette conjuguee a un membre de ladite paire homologue et une phase discontinue uniformement dispersee de particules discretes dans une phase aqueuse continue, ou les particules discretes creent des micromilieux qui permettent de faire la distinction entre l"etiquette associee a la particule - en phase discontinue - et l"etiquette en phase continue. Plusieurs conjugues et particules sont utilises dans la methode en question.
Designated States:
Publication Language: English (EN)
Filing Language: English (EN)