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1. US20130071892 - PROCESS FOR PRODUCTION OF POLYHYDROXYALKANOIC ACID USING GENETICALLY MODIFIED MICROORGANISM HAVING ENOYL-CoA HYDRATASE GENE INTRODUCED THEREIN

Office
États-Unis d'Amérique
Numéro de la demande 13580771
Date de la demande 22.02.2011
Numéro de publication 20130071892
Date de publication 21.03.2013
Type de publication A1
CIB
C12P 7/62
CCHIMIE; MÉTALLURGIE
12BIOCHIMIE; BIÈRE; SPIRITUEUX; VIN; VINAIGRE; MICROBIOLOGIE; ENZYMOLOGIE; TECHNIQUES DE MUTATION OU DE GÉNÉTIQUE
PPROCÉDÉS DE FERMENTATION OU PROCÉDÉS UTILISANT DES ENZYMES POUR LA SYNTHÈSE D'UN COMPOSÉ CHIMIQUE DONNÉ OU D'UNE COMPOSITION DONNÉE, OU POUR LA SÉPARATION D'ISOMÈRES OPTIQUES À PARTIR D'UN MÉLANGE RACÉMIQUE
7Préparation de composés organiques contenant de l'oxygène
62Esters des acides carboxyliques
CPC
C12P 7/625
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
7Preparation of oxygen-containing organic compounds
62Carboxylic acid esters
625Polyesters of hydroxy-carboxylic acids
Déposants Fukui Toshiaki
TOKYO INSTITUTE OF TECHNOLOGY
Orita Izumi
Mifune Jun
Kawashima Yui
Inventeurs Fukui Toshiaki
Orita Izumi
Mifune Jun
Kawashima Yui
Données relatives à la priorité 2010-043017 26.02.2010 JP
Titre
(EN) PROCESS FOR PRODUCTION OF POLYHYDROXYALKANOIC ACID USING GENETICALLY MODIFIED MICROORGANISM HAVING ENOYL-CoA HYDRATASE GENE INTRODUCED THEREIN
Abrégé
(EN)

The present invention intends to produce poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) [P(3HB-co-3HHx)] with a high 3-hydroxyhexanoic acid fraction using a vegetable oil as a basic raw material. In accordance with the present invention, there is provided a method of producing a microorganism that produces poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) with a high 3-hydroxyhexanoic acid fraction using a vegetable oil as a basic raw material, by introducing a gene encoding R-hydratase that converts a fatty acid β-oxidation system intermediate to a monomer, (R)-3-hydroxyacyl-CoA [R-3HA-CoA], into a recombinant Cupriavidus necator strain that was conferred an ability of producing P(3HB-co-3HHx).


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