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Paramétrages

Paramétrages

1. US20170189238 - APERTURED HYDROGEL COMPOSITIONS AND WOUND DRESSINGS

Note: Texte fondé sur des processus automatiques de reconnaissance optique de caractères. Seule la version PDF a une valeur juridique

Claims

1. A composition comprising:
a layer of water-swellable hydrogel, wherein the hydrogel has embedded therein a reinforcement sheet of liquid-water-permeable material,
wherein the layer of hydrogel has a wound-facing side and a non-wound-facing side and apertures extend through the layer of hydrogel from the wound-facing side to the non-wound-facing side and through the reinforcement sheet,
wherein the mean area of the apertures on at least one of the wound-facing side and non-wound-facing side of the hydrogel is at least 5 mm 2.
2. The composition according to claim 1, wherein the mean area of the apertures on at least one of the wound-facing side and non-wound-facing side of the layer of hydrogel is at least 10 mm 2.
3. The composition according to claim 1, wherein the mean area of the apertures on at least one of the wound-facing side and non-wound-facing side of the layer of hydrogel is at least 20 mm 2.
4. The composition according to claim 1, wherein the mean area of the apertures on at least one of the wound-facing side and non-wound-facing side of the layer of hydrogel is at least 20 mm 2 to 50 mm 2.
5. The composition according to claim 1, wherein the total area occupied by the apertures on the wound-facing side and/or non-wound-facing side of the layer of hydrogel is 60% or less of the total area of the layer of hydrogel.
6. The composition according to claim 5, wherein the layer of hydrogel has from about 1 to about 5 apertures per square 10 cm of the wound-facing side and/or non-wound-facing side.
7. The composition according to claim 1, wherein a polymeric film is disposed over the non-wound-facing side of the layer of hydrogel, the film having an MVTR of at least 100 g/m 2/24 hours, measured in accordance with BS EN 13726-2:2002.
8. The composition according to claim 1, wherein the mean area of the apertures on at least one of the wound-facing side and non-wound-facing side of the layer of hydrogel is at least 10 mm 2,
the layer of hydrogel has from about 1 to about 5 apertures per square 10 cm of the wound-facing side and/or non-wound-facing side,
the hydrogel is an ionic hydrogel, and
a polymeric film is disposed over the non-wound-facing side of the layer of hydrogel, the film having an MVTR of at least 100 g/m 2/24 hours, measured in accordance with BS EN 13726-2:2002.
9. The composition according to claim 8, wherein the polymeric film has an MVTR of from 1000 g/m 2/24 hours to 3000 g/m 2/24 hours, measured in accordance with BS EN 13726-2:2002.
10. The composition according to claim 9, wherein the polymeric film is continuous in that it extends over and covers each of the apertures in the layer of hydrogel.
11. The composition according to claim 10, wherein an absorbent layer is disposed between the layer of hydrogel and the polymeric film.
12. The composition according to claim 11, wherein the absorbent layer comprises a foamed hydrophilic material.
13. The composition according to claim 12, wherein the foamed hydrophilic material is selected from a foamed polyurethane and a foamed hydrogel.
14. The composition according to claim 9, wherein a further polymeric film is disposed over and in contact with the non-wound-facing side of the layer of hydrogel, the further polymeric film having an MVTR of at least 100 g/m 2/24 hours, measured in accordance with BS EN 13726-2:2002, and the polymeric films are adhered together by a layer of adhesive.
15. The composition according to claim 14, wherein the further polymeric film has apertures therein, at least some of which overlie the apertures in the layer of hydrogel, and the polymeric film disposed further away from the non-wound-facing side of the layer of hydrogel is continuous in that it extends over and covers each of the apertures in the layer of hydrogel and/or the further polymeric layer.
16. The composition according to claim 15, wherein the layer of adhesive has apertures therein, at least some of which overlie the apertures in the layer of hydrogel and/or the apertures of the further polymeric film.
17. The composition according to claim 16, wherein the layer of hydrogel is 3 mm or less in thickness, measured from the wound-facing side to the non-wound-facing side.
18. A method of forming a composition comprising:
providing a layer of water-swellable hydrogel, wherein the hydrogel has embedded therein a reinforcement sheet of liquid water-permeable material, the layer of hydrogel having a wound-facing side and a non-wound-facing side;
cutting apertures through the layer of water-swellable hydrogel and the reinforcement sheet embedded therein to form apertures that extend through the layer of hydrogel from the wound-facing side to the non-wound-facing side and through the reinforcement sheet,
wherein the mean area of the apertures on at least one of the wound-facing side and non-wound-facing side of the hydrogel is at least 5 mm 2.
19. The method according to claim 18, wherein the method involves die cutting the apertures.
20. The method according to claim 18, wherein the method further involves placing a continuous polymeric film over the non-wound-facing side of the layer of hydrogel, the film having an MVTR of at least 100 g/m 2/24 hours, measured in accordance with BS EN 13726-2:2002, wherein the polymeric film is continuous in that it extends over and covers each of the apertures in the layer of hydrogel.
21- 25. (canceled)