Traitement en cours

Veuillez attendre...

Paramétrages

Paramétrages

Aller à Demande

1. EP2639239 - Élimination d'agrégats de protéines à partir de préparations biopharmaceutiques dans un mode de transfert

Office
Office européen des brevets (OEB)
Numéro de la demande 13275053
Date de la demande 12.03.2013
Numéro de publication 2639239
Date de publication 18.09.2013
Type de publication B1
CIB
C07K 1/16
CCHIMIE; MÉTALLURGIE
07CHIMIE ORGANIQUE
KPEPTIDES
1Procédés généraux de préparation de peptides
14Extraction; Séparation; Purification
16par chromatographie
C07K 1/18
CCHIMIE; MÉTALLURGIE
07CHIMIE ORGANIQUE
KPEPTIDES
1Procédés généraux de préparation de peptides
14Extraction; Séparation; Purification
16par chromatographie
18Chromatographie d'échange d'ions
CPC
B01D 15/362
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
15Separating processes involving the treatment of liquids with solid sorbents
08Selective adsorption, e.g. chromatography
26characterised by the separation mechanism
36involving ionic interaction
361Ion-exchange
362Cation-exchange
C07K 1/165
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
1General methods for the preparation of peptides ; , i.e. processes for the organic chemical preparation of peptides or proteins of any length
14Extraction; Separation; Purification
16by chromatography
165mixed-mode chromatography
C07K 1/18
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
1General methods for the preparation of peptides ; , i.e. processes for the organic chemical preparation of peptides or proteins of any length
14Extraction; Separation; Purification
16by chromatography
18Ion-exchange chromatography
B01D 15/363
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
15Separating processes involving the treatment of liquids with solid sorbents
08Selective adsorption, e.g. chromatography
26characterised by the separation mechanism
36involving ionic interaction
361Ion-exchange
363Anion-exchange
B01D 15/3809
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
15Separating processes involving the treatment of liquids with solid sorbents
08Selective adsorption, e.g. chromatography
26characterised by the separation mechanism
38involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
3804Affinity chromatography
3809of the antigen-antibody type, e.g. protein A, G, L chromatography
B01J 39/20
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
39Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
08Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
16Organic material
18Macromolecular compounds
20obtained by reactions only involving unsaturated carbon-to-carbon bonds
Déposants MERCK PATENT GMBH
Inventeurs KOZLOV MIKHAIL
CATALDO WILLIAM
POTTY AJISH
GALIPEAU KEVIN
HAMZIK JAMES
UMANA JOAQUIN
PEECK LARS
États désignés
Données relatives à la priorité 201261609533 12.03.2012 US
201261666578 29.06.2012 US
Titre
(DE) Beseitigung von Proteinaggregaten aus biopharmazeutischen Präparaten in einem Durchflussmodus
(EN) Removal of Protein Aggregates from Biopharmaceutical Preparations in a Flow-Through Mode
(FR) Élimination d'agrégats de protéines à partir de préparations biopharmaceutiques dans un mode de transfert
Abrégé
(EN) The present invention provides compositions and methods for removal of protein aggregates from a sample in a flow-through mode using a cation exchange material with a ionic capacity of 1 to 30 mM.