Traitement en cours

Veuillez attendre...

Paramétrages

Paramétrages

Aller à Demande

1. CN114174813 - Systems and methods for diagnosing biological conditions associated with periodic changes in metal metabolism

Office
Chine
Numéro de la demande 202080054081.7
Date de la demande 05.06.2020
Numéro de publication 114174813
Date de publication 11.03.2022
Type de publication A
CIB
G01N 23/223
GPHYSIQUE
01MÉTROLOGIE; TESTS
NRECHERCHE OU ANALYSE DES MATÉRIAUX PAR DÉTERMINATION DE LEURS PROPRIÉTÉS CHIMIQUES OU PHYSIQUES
23Recherche ou analyse des matériaux par l'utilisation de rayonnement (ondes ou particules), p.ex. rayons X ou neutrons, non couvertes par les groupes G01N3/-G01N17/201
22en mesurant l'émission secondaire de matériaux
223en irradiant l'échantillon avec des rayons X ou des rayons gamma et en mesurant la fluorescence X
CPC
G01N 30/72
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
30Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography ; or field flow fractionation;
02Column chromatography
62Detectors specially adapted therefor
72Mass spectrometers
G16H 50/20
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
50ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
20for computer-aided diagnosis, e.g. based on medical expert systems
G16B 40/00
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
40ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
Déposants WEINSHAN YIKAN MEDICAL COLLEGE
西奈山伊坎医学院
Inventeurs ARORA MANISH
M·阿罗拉
CURTIN PAUL
P·柯廷
AUSTIN CHRISTOPHER
C·奥斯汀
Mandataires 深圳市百瑞专利商标事务所(普通合伙) 44240
Données relatives à la priorité 62/858,260 06.06.2019 US
Titre
(EN) Systems and methods for diagnosing biological conditions associated with periodic changes in metal metabolism
(ZH) 用于诊断与金属代谢的周期性变化相关的生物病症的系统和方法
Abrégé
(EN) A method for assessing a biological condition associated with metal metabolism in a subject, the method comprising sampling a location along a biological sample of the subject to obtain a number of ion samples. Each ion sample corresponds to a location on the biological sample, and each location represents an amount of growth of the biological sample. The obtained ions are analyzed with a mass spectrometer, thereby obtaining a plurality of traces. Each such trace represents a concentration over time of a corresponding elemental isotope of a plurality of elemental isotopes. A set of features is derived from the trace. Each feature is determined by a change in a single isotope or combination of isotopes in the plurality of traces. The set of features is input into a trained classifier to obtain a probability that the subject has the biological condition associated with metal metabolism.
(ZH) 一种用于评估受试者的与金属代谢相关的生物病状的方法,所述方法包含对沿所述受试者的生物样品的位置进行采样以获得若干个离子样品。每个离子样品对应于所述生物样品上的一个位置,并且每个位置表示所述生物样品的生长量。用质谱仪分析所获得的离子,由此获得多个迹线。每个此类迹线表示多种元素同位素中的对应元素同位素随时间推移的浓度。从所述迹线中得出一组特征。每个特征由所述多个迹线中的单个同位素或同位素组合的变化确定。将所述一组特征输入到经训练的分类器中,以获得所述受试者患有所述与金属代谢相关的生物病状的概率。