(EN) The present invention discloses a surface-drug-loading vertebroplasty dilatation balloon and a preparation method thereof. The surface-drug-loading vertebroplasty dilatation balloon comprises a balloon body, a drug-loading film is attached on surface of the balloon body, the drug-loading film is composed of at least two drug-loading coating layers, and the first drug-loading coating layer directlycontacting the balloon body is formed by electrospinning. The surface of the balloon body is provided with the drug-loading film, and the drug-loading film is composed of a plurality of the drug-loading coating layers, can be retained in body after the balloon is withdrawn, forms an outer shell enclosing bone cement, plays a function of effectively releasing the drugs at desired sites, improves function efficiency of the drugs, and also prevents the bone cement from detaching from positions. The vertebroplasty dilatation balloon has multiple functions, improves postoperative effects of percutaneous vertebroplasty and percutaneous kyphoplasty, and is especially suitable for treatments of osteoporosis and related compression fractures.
(ZH) 本发明公开了一种表面载药的椎体成形扩张球囊及其制备方法,其包括球囊本体,在球囊本体表面附有载药膜,所述载药膜由至少两层的载药涂层组成,其中,与球囊本体直接接触的第一层载药涂层通过静电纺丝形成。本发明在球囊本体表面设置载药膜,载药膜由多层的载药涂层构成,载药膜在球囊撤出后能够保留在体内,形成包裹骨水泥的外壳,既起到了向所需部位有效释放药物的作用,提高了药物的作用效率,又起到了防止骨水泥脱离位置的作用,功能多面,提高了经皮椎体成形术和经皮椎体后凸成形术的术后效果,尤其适合于骨质疏松以及相关压缩性骨折的治疗。