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1. WO2020163179 - CADRE EXTENSIBLE PAR BALLONNET POUR L'IMPLANTATION TRANSCATHÉTER D'UNE PROTHÈSE DE VALVULE CARDIAQUE

Note: Texte fondé sur des processus automatiques de reconnaissance optique de caractères. Seule la version PDF a une valeur juridique

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CLAIMS

What is claimed is:

1. A transcatheter valve prosthesis comprising:

a stent having a crimped configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve, wherein the stent is balloon expandable, the stent including

an inflow portion formed proximate to an inflow end of the stent, the inflow portion including a plurality of crowns and a plurality of struts with each crown being formed between a pair of opposing struts, a plurality of side openings being defined by the plurality of crowns and the plurality of struts, wherein endmost inflow side openings and endmost inflow crowns are formed at the inflow end of the stent and the inflow end of the stent has a total of twelve endmost inflow crowns,

an outflow portion formed proximate to an outflow end of the stent, the outflow portion including a plurality of crowns and a plurality of struts with each crown being formed between a pair of opposing struts, wherein endmost outflow crowns are formed at the outflow end of the stent and the outflow end of the stent has a total of six endmost outflow crowns, and wherein a diameter of the inflow end of the stent is the same as a diameter of the outflow end of the stent, and

a transition portion extending between the inflow portion and the outflow portion, and

a prosthetic valve disposed within and secured to at least the transition portion of the stent, the prosthetic valve being configured to block blood flow in one direction to regulate blood flow through a central lumen of the stent.

2. The transcatheter valve prosthesis of claim 1, wherein the prosthetic valve includes three leaflets and three commissures, each commissure being formed by attached adjacent lateral ends of an adjoining pair of the three leaflets.

3. The transcatheter valve prosthesis of claim 2, wherein the transition portion includes a total of six axial frame members, each axial frame member extending between a crown of the outflow portion and a crown of the inflow portion and each axial frame member disposed approximately halfway between a pair of adjacent endmost outflow crowns, and wherein three

of the six axial frame members are aligned with and attached to a respective commissure of the three leaflets of the prosthetic valve.

4. The transcatheter valve prosthesis of claim 2, wherein the three leaflets are attached to the stent along a margin of attachment that follows struts and nodes of the inflow portion of the stent, a node being defined as a region where two crowns of the plurality of crowns within the inflow portion connect, wherein the margin of attachment has a smooth concave shape and wherein the two crowns that connect at each node overlap.

5. The transcatheter valve prosthesis of claim 2, wherein struts adjacent to the six endmost outflow crowns are endmost struts and a plurality of holes are formed within the endmost struts, the plurality of holes configured to attach a respective commissure of the three leaflets of the prosthetic valve to the stent.

6. The transcatheter valve prosthesis of claim 5, wherein the transition region is formed by a connection between abutting crowns of the outflow portion and crowns of the inflow portion, the connection having an increased width relative to the plurality of struts of the outflow portion.

7. The transcatheter valve prosthesis of claim 5, wherein a generally triangular material flap is attached to the plurality of holes and the respective commissure of the three leaflets of the prosthetic valve is attached to the generally triangular material flap.

8. The transcatheter valve prosthesis of claim 2, wherein the transition portion includes a total of six axial frame members, each axial frame member including a planar base and two spaced apart legs longitudinally extending from the planar base, the planar base having an increased width relative to the plurality of struts of the outflow portion and each leg being attached to a crown of the inflow portion.

9. The transcatheter valve prosthesis of claim 8, wherein the legs radially extend from the planar base when the stent is in the expanded configuration and wherein a generally diamond shaped material flap is attached to three of the axial frame members and the respective commissure of the three leaflets of the prosthetic valve is attached to the generally diamond shaped material flap.

10. The transcatheter valve prosthesis of claim 2, wherein the transition portion includes a total of six axial frame members, each axial frame member including two spaced apart legs radially and longitudinally extending from a crown of the outflow portion, each leg being attached to a crown of the inflow portion.

11. The transcatheter valve prosthesis of claim 10, wherein a generally diamond-shaped material flap is attached to three of the axial frame members and the respective commissure of the three leaflets of the prosthetic valve is attached to the generally diamond-shaped material flap.

12. The transcatheter valve prosthesis of claim 10, wherein struts of the inflow portion alternate between a first thickness and a second thickness, the second thickness being greater than the first thickness.

13. The transcatheter valve prosthesis of claim 1, wherein the transition portion includes a total of six axial frame members, each axial frame member attached to a respective endmost outflow crown.

14. The transcatheter valve prosthesis of claim 1, wherein the transition portion includes a total of six axial frame members and a total of six endmost outflow side openings are formed at the outflow end of the stent, each endmost outflow side opening being defined by two struts of the outflow portion, four struts of the inflow portion, and two axial frame members of the transition portion.

15. The transcatheter valve prosthesis of claim 1, wherein at least one strut of the inflow portion is tapered and the thickness varies along a length thereof such that a middle portion is relatively thinner than opposing end portions of the strut.

16. A transcatheter valve prosthesis comprising:

a stent having a crimped configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve, wherein the stent is balloon expandable, the stent including

an inflow portion formed proximate to an inflow end of the stent, the inflow portion including a plurality of crowns and a plurality of struts with each crown being formed between a pair of opposing struts, a plurality of side openings being defined by the plurality of crowns and the plurality of struts, wherein endmost inflow side openings and endmost inflow crowns are formed at the inflow end of the stent and the inflow end of the stent has a total of twelve endmost inflow crowns, and

an outflow portion formed proximate to an outflow end of the stent, wherein the outflow end of the stent has a total of three commissure posts, each commissure post longitudinally extending from a crown of the inflow end and the three commissure posts being circumferentially spaced apart, and wherein a diameter of the inflow end of the stent is the same as a diameter of the outflow end of the stent, and

a prosthetic valve disposed within and secured to at least a portion of the stent, the prosthetic valve being configured to block blood flow in one direction to regulate blood flow through a central lumen of the stent.

17. A transcatheter valve prosthesis comprising:

a stent having a crimped configuration for delivery within a vasculature and an expanded configuration for deployment within a native heart valve, wherein the stent is balloon expandable, the stent including

a plurality of axial frame members,

an inflow portion including at least three rows of struts and crowns formed between adjacent pairs of said struts, wherein the at least three rows of the inflow portion are formed between an inflow end of the axial frame members and an inflow end of the stent, and an outflow portion including a single row of struts and crowns formed between adjacent pair of said struts, the outflow portion being coupled to an outflow end of the axial frame members, wherein exactly two struts of the plurality of struts of the outflow portion are disposed between adjacent axial frame members.

18. The transcatheter valve prosthesis of claim 17,

wherein the plurality of axial frame members includes exactly six axial frame members, wherein three of the six axial frame members are commissure posts and three of the six axial frame members are axial struts, and

wherein each of the axial struts is disposed between adjacent commissure posts.

19. The transcatheter valve prosthesis of claim 18, further compering a prosthetic valve including three leaflets, wherein each commissure of the leaflets is coupled to a corresponding commissure post of the stent.

20. The transcatheter valve prosthesis of claim 17, wherein one of the at least three rows of struts and crowns of the inflow portion includes crowns coupled to inflow end of the axial frame member, wherein the one row includes exactly four struts between adjacent axial frame members.