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1. WO2021064132 - TRAITEMENT DU SYNDROME DE LA MÉNOPAUSE ET/OU DES SYMPTÔMES ASSOCIÉS À LA MÉNOPAUSE


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INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/EP2020/077579 P6060157PCT
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
01 October 2020 01 October 2019
Applicant
BESINS HEALTHCARE IRELAND LIMITED
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No. ____________
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     A61K 31/19 (2006.01)i; A61K 31/353 (2006.01)i; A61K 31/365 (2006.01)i; A61K 31/375 (2006.01)i; A61K 31/4045 (2006.01)i; A61K 31/728 (2006.01)i; A61K 33/06 (2006.01)i; A61K 36/15 (2006.01)i; A61K 36/16 (2006.01)i; A61K 36/28 (2006.01)i; A61K 36/71 (2006.01)i; A61K 36/84 (2006.01)i; A61P 15/12 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     A61K; A61P
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, BIOSIS, CHEM ABS Data, WPI Data, EMBASE

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
X
JP 2006111541 A (TOYO SHINYAKU KK) 27 April 2006 (2006-04-27)
13
Manufacture example 2;paragraph [0077]
(2)
X
CIOTTA L ET AL, "M087 TREATMENT WITH HYALURONIC ACID + CONDROITIN SULFATE OF GENITO-URINARY SUBJECTIVE DISTURBANCES OF WOMEN IN POST-MENOPAUSE", INTERNATIONAL JOURNAL OF GYNECOLOGY AND OBSTETRICS,Vol. 119, 2012,
XP028949605
1-16
the whole document
(3)
Y
CAPPELLI V ET AL, "[Evaluation of the efficacy of a new nutraceutical product in the treatment of postmenopausal symptoms].", MEDLINE December 2015 (2015-12), Database accession no. NLM26788874
Retrieved from the Internet:
URL:US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US
XP002798386
1-16
abstract
(4)
Y
TERAUCHI MASAKAZU ET AL, "Effects of grape seed proanthocyanidin extract on menopausal symptoms, body composition, and cardiovascular parameters in middle-aged women: a randomized, double-blind, placebo-controlled pilot study.", MEDLINE September 2014 (2014-09), Database accession no. NLM24518152
Retrieved from the Internet:
URL:US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US
XP002798387
1-16
abstract
& TERAUCHI MASAKAZU ET AL, "Effects of grape seed proanthocyanidin extract on menopausal symptoms, body composition, and cardiovascular parameters in middle-aged women: a randomized, double-blind, placebo-controlled pilot study.",  MENOPAUSE (NEW YORK, N.Y.) SEP 2014,Vol. 21, No. 9, September 2014 (2014-09), page 990-996,
(5)
Y
SEYED BAHMAN PANAHANDE ET AL, "Effects of French maritime pine bark extract (Oligopin ) supplementation on bone remodeling markers in postmenopausal osteopenic women: A randomized clinical trial", PHYTOTHERAPY RESEARCH.,Vol. 33, No. 4, 24 March 2019 (2019-03-24), page 1233-1240,
XP055677603
1-16
the whole document
table 2
(6)
Y
MIELNIK JETZY, "P318 Extract of cimicifuga racemosa in the treatment of neurovegetative symptoms in women in the perimenopausal period", MATURITAS,Vol. 27, November 1996 (1996-11), page 215,
XP028900899
1-16
the whole document
(7)
Y
SHARLA L POWELL ET AL, "In Vitro Serotonergic Activity of Black Cohosh and Identification of N-omega-Methylserotonin as a Potential Active Constituent", 24 December 2008 (2008-12-24), Vol. 56, No. 24, page 11718-11726,
XP002620988
[retrieved on  2008-12-02]
1-16
page 11718, right-hand column, paragraph 1
page 11724, right-hand column, paragraph 3
(8)
Y
BORRELLI F ET AL, "Alternative and complementary therapies for the menopause", 01 August 2010 (2010-08-01), Vol. 66, No. 4, page 333-343,
XP027148038
[retrieved on  2010-07-16]
1-16
the whole document
§§ 3.1, 3.8
table 5
(9)
Y
EKBATANIN N NAZEM ET AL, "Can valerian improve menopausal sleep quality?", JOURNAL OF NEUROLOGICAL SCIENCES,Vol. 333, 2013,
XP028721080
1-16
the whole document
(10)
Y
HAESEONG PARK ET AL, "A pilot phase II trial of magnesium supplements to reduce menopausal hot flashes in breast cancer patients", SUPPORTIVE CARE IN CANCER, SPRINGER-VERLAG, DE,Vol. 19, No. 6, 27 January 2011 (2011-01-27), page 859-863,
XP019896214
1-16
abstract
figure 1
(11)
Y
TASCIOGLU A ET AL, "In vitroandin silicoevaluation of aromatase inhibitory activity of apigenin and amentoflavone; dual benefit of St. John's Wort in postmenopausal women", TOXICOLOGY LETTERS,Vol. 258, 2016,
XP029714182
1-16
the whole document
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
JP 2006111541 A
27 April 2006
NONE
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
30 November 2020
Date of mailing of the international search report:
08 December 2020
Authorized officer:
Collura, Alessandra
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