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1. WO1988004690 - NOUVEAUX ACTIVATEURS DE PLASMINOGENE

Note: Texte fondé sur des processus automatiques de reconnaissance optique de caractères. Seule la version PDF a une valeur juridique

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Claims :

1. A plasminogen activator selected from the group consisting of Fg. tPA/UK410, Fg. tPA/UK410/366 and tPPUK410/366 and UK-K2 410/366.

2. A recombinant DNA molecule comprising a coding sequence for a plasminogen activator selected from the group consisting of Fg. tPA/UK410, Fg. tPA/UK410/366 or tPPUK410/366 and UK-K2 410/366.

3. The recombinant DNA molecule of claim 2 which is a mammalian expression vector and in which the plasminogen activator coding sequence is fused in-frame to a regulatory region.

4. A transformed mammalian cell which comprises the recombinant DNA molecule of claim 3.

5. A pharmaceutical composition comprising the plasminogen activator of claim 1 and a pharmaceutically acceptable carrier therefore.

6. A process for preparing a plasminogen activator which comprises culturing transformed mammalian cells of claim 4 and isolating the plasminogen activator produced thereby.