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1. ZA2004/02440 - USE OF ANNELLATED PYRROLE COMPOUNDS IN THE TREATMENT OF ARTICULAR CARTILAGE OR SUBSCHONDRAL BONE DEGENERATION

Office
Afrique du Sud
Numéro de la demande 2004/02440
Date de la demande 29.03.2004
Numéro de publication 2004/02440
Date de publication 29.12.2004
Type de publication B
CIB
A61K
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
CPC
A61K 31/40
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61P 19/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
Déposants MERCKLE GMBH
ASCENTIA PHARMA INC
Inventeurs Johanne MARTEL-PELLETIER
Jean-Pierre PELLETIER
Mandataires HAHN & HAHN
Données relatives à la priorité 2356099 30.08.2001 CA
60/315 773 30.08.2001 US
Titre
(EN) USE OF ANNELLATED PYRROLE COMPOUNDS IN THE TREATMENT OF ARTICULAR CARTILAGE OR SUBSCHONDRAL BONE DEGENERATION
Abrégé
(EN)
degeneration or destruction of articul cartilage and/or subchondral bo in the affected joint of a mamm is accomplished by administering compound of formula (I), wherein t variables have the meanings given the present description. A preferr compound of formula (I) is formula ( This treatment ameliorates, diminish actively treats, reverses or prevents a

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