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1. RU02303447 - METHOD FOR APPLYING ANNEALED PYRROLE COMPOUNDS WHEN TREATING ARTICULAR CARTILAGE DEGENERATION OR STRUCTURAL SUBCHONDRAL BONE TRANSFORMATIONS

Office
Fédération de Russie
Numéro de la demande 2004109227/15
Date de la demande 29.08.2002
Numéro de publication 02303447
Date de publication 27.07.2007
Numéro de délivrance
Date de délivrance 27.07.2007
Type de publication C2
CIB
A61K 31/40
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
31Préparations médicinales contenant des ingrédients actifs organiques 
33Composés hétérocycliques
395ayant l'azote comme hétéro-atome d'un cycle, p.ex. guanéthidine ou rifamycines
40ayant des cycles à cinq chaînons avec un azote comme seul hétéro-atome d'un cycle, p.ex. sulpiride, succinimide, tolmétine, buflomédil
A61P 19/02
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
PACTIVITÉ THÉRAPEUTIQUE SPÉCIFIQUE DE COMPOSÉS CHIMIQUES OU DE PRÉPARATIONS MÉDICINALES
19Médicaments pour le traitement des troubles du squelette
02des troubles articulaires, p.ex. arthrites, arthroses
CPC
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 31/40
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61K 31/498
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
A61K 31/538
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
535having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
53751,4-Oxazines, e.g. morpholine
538ortho- or peri-condensed with carbocyclic ring systems
A61K 31/5415
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
54having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
5415ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
Inventeurs PELLET'E Zhan-P'er (CA)
ПЕЛЛЕТЬЕ Жан-Пьер (CA)
MARTEL'-PELLET'E Zhoann (CA)
МАРТЕЛЬ-ПЕЛЛЕТЬЕ Жоанн (CA)
Données relatives à la priorité 2356099 30.08.2001 CA
60/315,773 30.08.2001 CA
Titre
(EN) METHOD FOR APPLYING ANNEALED PYRROLE COMPOUNDS WHEN TREATING ARTICULAR CARTILAGE DEGENERATION OR STRUCTURAL SUBCHONDRAL BONE TRANSFORMATIONS
(RU) ПРИМЕНЕНИЕ АННЕЛИРОВАННЫХ СОЕДИНЕНИЙ ПИРРОЛА ПРИ ЛЕЧЕНИИ ДЕГЕНЕРАЦИИ СУСТАВНОГО ХРЯЩА ИЛИ СТРУКТУРНЫХ ИЗМЕНЕНИЙ СУБХОНДРАЛЬНОЙ КОСТИ
Abrégé
(EN)
FIELD: medicine.SUBSTANCE: method involves introducing drug of formula (I) where variables have known values shown in invention application.EFFECT: increased treatment efficiency; reversed or prevented articular cartilage or subchondral bone degeneration.10 cl, 10 dwg

(RU)
Изобретение относится к медицине. Описано лечение или профилактика дегенерации или деструкции суставного хряща и/или субхондральной кости в поврежденном суставе млекопитающего, заключающееся во введении соединения формулы (I), где переменные имеют значения, данные в настоящем описании. Это лечение улучшает, усиливает эффект лечения, реверсирует или предотвращает любую дегенерацию или деструкции суставного хряща и/или субхондральной кости, являющуюся результатом ранней стадии указанной дегенерации. 4 н. и 6 з.п. ф-лы, 10 ил.

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