Traitement en cours

Veuillez attendre...

Paramétrages

Paramétrages

Aller à Demande

1. WO2021058956 - PROCÉDÉ D'OBTENTION DE CELLULES DE TYPE BASAL DES VOIES RESPIRATOIRES DÉRIVÉES DE CELLULES SOUCHES PLURIPOTENTES ET MODÈLE D'ÉPITHÉLIUM DES VOIES RESPIRATOIRES


Avertissement La version image (PDF) disponible dans PATENTSCOPE est la version officielle. Cette version HTML en ligne est fournie pour aider les utilisateurs. Malgré le grand soin apporté à la compilation pour assurer une représentation précise et exacte des données figurant sur le document/les images imprimés, des erreurs et/ou des omissions ne peuvent pas être exclues en raison des processus de transmission et de conversion de données et des limitations inhérentes aux processus de traduction (éventuellement) automatique utilisés. Les liens hypertexte suivis de ce symbole sont associés à des ressources externes qui ne sont pas contrôlées par l'OMPI. L'OMPI décline toute responsabilité concernant les points mentionnés ci-dessus.

INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/GB2020/052310 P000406.WO
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
23 September 2020 26 September 2019
Applicant
NEWCELLS BIOTECH LIMITED
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No.     2a    
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     C12N 5/071 (2010.01)i; C12N 7/00 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     C12N; C07K
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, BIOSIS, EMBASE, WPI Data

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
X
COLIN R. BUTLER ET AL, "Rapid Expansion of Human Epithelial Stem Cells Suitable for Airway Tissue Engineering", AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE.,Vol. 194, No. 2, 15 July 2016 (2016-07-15), page 156-168,
XP055693474
1-34
material and methods;figures 1, 6, 7
(2)
X
JASON R. ROCK ET AL, "Basal cells as stem cells of the mouse trachea and human airway epithelium.", PNAS,Vol. 106, No. 31, 01 January 2009 (2009-01-01), page 12771-12775,
XP055080161
16,17,19
page 12774, right-hand column; figure 4
(3)
X
MILLER ALYSSA J ET AL, "Generation of lung organoids from human pluripotent stem cells in vitro", 21 January 2019 (2019-01-21), Vol. 14, No. 2, page 518-540,
XP036687606
[retrieved on  2019-01-21]
1-27
material and methods;figure 1
(4)
X
SARAH X L HUANG ET AL, "Efficient generation of lung and airway epithelial cells from human pluripotent stem cells", NATURE BIOTECHNOLOGY,01 December 2013 (2013-12-01),
XP055091029
1-27
figures 1, 2, 5
(5)
X
EP 3272859 A1 (UNIV KYOTO [JP]) 24 January 2018 (2018-01-24)
1-27
example 1
(6)
A
AMJAD HORANI ET AL, "Rho-Associated Protein Kinase Inhibition Enhances Airway Epithelial Basal-Cell Proliferation and Lentivirus Transduction", AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY.,Vol. 49, No. 3, 01 September 2013 (2013-09-01), page 341-347,
XP055693472
1-34
material and methods;figure 1
(7)
A
FENG LI ET AL, "Diversity of Epithelial Stem Cell Types in Adult Lung", STEM CELLS INTERNATIONAL,Vol. 2015, 01 January 2015 (2015-01-01), page 1-11,
XP055693484
1-34
the whole document
(8)
X,P
FINN J. HAWKINS ET AL, "Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells", CELL STEM CELL,21 February 2020 (2020-02-21),
XP055755037
1-34
material and methods;figures 1-5
(9)
X,P
ABO KRISTINE M ET AL, "Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors.", BIORXIV : THE PREPRINT SERVER FOR BIOLOGY 04 JUN 2020,04 June 2020 (2020-06-04),
XP002801268
28-34
material and methods
(10)
X,P
LIU XUEFENG ET AL, "Conditionally Reprogrammed Human Normal Airway Epithelial Cells at ALI: A Physiological Model for Emerging Viruses", 01 June 2020 (2020-06-01), Vol. 35, No. 3, page 280-289,
XP037184847
[retrieved on  2020-06-17]
28-34
figures 1-3
(11)
T
NISHIGA MASATAKA ET AL, "COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives", 20 July 2020 (2020-07-20), Vol. 17, No. 9, page 543-558,
XP037218263
[retrieved on  2020-07-20]
the whole document
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
EP 3272859 A1
24 January 2018
CA 2980270 A1
EP 3272859 A1
JP 6730709 B2
JP WO2016148307 A1
US 2018112186 A1
WO 2016148307 A1
22 September 2016
24 January 2018
29 July 2020
28 December 2017
26 April 2018
22 September 2016
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
30 November 2020
Date of mailing of the international search report:
09 December 2020
Authorized officer:
Trommsdorff, Marion
Top    Part 1: 1 2 3 4 5 6         Part 2: A B C D E