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1. SG180677 - METHOD FOR TREATING HEART FAILURE WITH STRESSCOPIN-LIKE PEPTIDES

Office
Singapour
Numéro de la demande 2012032603
Date de la demande 04.11.2010
Numéro de publication 180677
Date de publication 28.06.2012
Type de publication A
CIB
A61K 38/22
ANÉCESSITÉS COURANTES DE LA VIE
61SCIENCES MÉDICALE OU VÉTÉRINAIRE; HYGIÈNE
KPRÉPARATIONS À USAGE MÉDICAL, DENTAIRE OU POUR LA TOILETTE
38Préparations médicinales contenant des peptides
16Peptides ayant plus de 20 amino-acides; Gastrines; Somatostatines; Mélanotropines; Leurs dérivés
17provenant d'animaux; provenant d'humains
22Hormones
Déposants JANSSEN PHARMACEUTICA NV
Inventeurs GENGO, PETER, J.
SABBAH, HANI, N.
SHANKLEY, NIGEL, P.
Données relatives à la priorité 12612548 04.11.2009 US
61/258,181 04.11.2009 US
Titre
(EN) METHOD FOR TREATING HEART FAILURE WITH STRESSCOPIN-LIKE PEPTIDES
Abrégé
(EN)
The present invention relates to novel methods of treating heart failure comprising administering an amount of stresscopin-like peptide to a subject in need thereof; and substantially maintaining the amount of said peptide present in the plasma of said subject at a concentration resulting in a therapeutic benefit without a substantial increase in the heart rate of said subject. The method involves the use of stresscopin-like peptides that are selective corticotrophin releasing hormone receptor type 2 (CRHR2) agonists.

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