WO/2016/190723 THE DETERMINATION METHOD OF THE HIGH CARDIOVASCULAR RISK INDICATORS IN THE CASE OF CENTRAL OBSESITY IN PATIENTS FROM BALTIC SEA REGION||WO||01.12.2016|
||PCT/LV2016/000002||RÍGAS STRADIŅA UNIVERSITÁTE||VOICEHOVSKA, Júlija|
The invention relates to medicine, internal medicine, general medicine, general physicians, cardiology, endocrinology, gerontology, dermatology. A non-invasive, valid method for the assessment of high cardiovascular risk score in central obesity patients of the Baltic region is developed. Changes of 2 and more characteristics that contribute to skin appearance are definied, so if these include 6-8 and above papillomas, 2 or 3 and above keratosis and lentigo zones, and/or 4-6 gravitational wrinkles, high cardiovascular risk is established.
WO/2016/159747 ETHYNYLXANTHINES, PREPARATION AND USE AS CALCIUM ION CHANNEL MODULATORS||WO||06.10.2016|
||PCT/LV2015/000003||LATVIAN INSTITUTE OF ORGANIC SYNTHESIS||ARSENJANS, Pavels|
The present invention relates to novel pharmaceutical compounds, which exhibit ability to act as calcium ion channel modulators, methods for their synthesis and the treatment and/or prevention of various diseases and disorders including deregulated calcium ion channel activity.
WO/2016/159746 NOVEL ETHYNYLXANTHINES, THEIR PREPARATION AND USE AS INHIBITORS OF MATRIX METALLOPROTEINASES AND ANGIOGENESIS||WO||06.10.2016|
||PCT/LV2015/000002||LATVIAN INSTITUTE OF ORGANIC SYNTHESIS||ARSENJANS, Pavels|
The present invention relates to a novel ethynylxanthine derivatives of formula (I) which exhibit ability selectively suppress matrix metalloproteinases and therefore may act as inhibitors of angiogenesis, methods for their synthesis and use for the treatment and/or prevention of various diseases and disorders caused by overexpression of matrix metalloproteinases by administration of such substances.
WO/2016/159745 ETHYNYLXANTHINES, PREPARATION AND USE FOR CANCER TREATMENT||WO||06.10.2016|
||PCT/LV2015/000001||LATVIAN INSTITUTE OF ORGANIC SYNTHESIS||ARSENJANS, Pavels|
The present invention relates to novel ethynylxanthine derivatives of formula (I) which exhibit high antiproliferative activity against various tumor cell lines, methods for their synthesis and use for the treatment and/or prevention of cancer.
WO/2016/129983 NOVEL N-ACYL-ARYLSULFONAMIDE DERIVATIVES AS AMINOACYL-TRNA SYNTHETASE INHIBITORS||WO||18.08.2016|
||PCT/LV2016/000001||LATVIAN INSTITUTE OF ORGANIC SYNTHESIS||JIRGENSONS, Aigars|
The present invention relates to novel N-acyl-diarysulfonamides acting as inhibitors of bacterial aminoacyl-tRNA synthetase. These can be used as medicines or as constituent of medicines for the treatment of bacterial infections.
WO/2016/072824 A FOLD ABLE DEVICE FOR PREPARING FOOD ON AN OPEN FIRE||WO||12.05.2016|
||PCT/LV2015/000008||CVETKOVS, Andris||CVETKOVS, Andris|
The invention relates to devices for preparing food on an open fire. A device has been developed for preparing food on an open fire that is compact, fast and easy to assemble, and convenient for use, even on a hiking tour. The device, containing a barbecue grill which can be opened with a handle, additionally comprises two separate identical supports, where each support is designed as a pointed rod in order to fix it firmly in the soil and connected in the upper part by means of a U-shaped clamp to support the barbecue grill; and containing a rod-shaped grill holder, where one end is folded at a 90 degree angle forming a bracing element of the top edge of the grill, and the other end is folded at a 90 degree angle and sharpened in order to fix it firmly in the soil, and fitted with a handle; furthermore, the holder is divisible in its middle section.
WO/2016/039605 BRAIN TISSUE POST-MORTEM DETECTION TECHNIQUES FOR PATHOMORPHOLOGIC BRAIN EXAMINATION IN CASE OF ENCEPHALOPATHY||WO||17.03.2016|
||PCT/LV2014/000012||RĪGAS STRADIŅA UNIVERSITĀTE||ROGA, Silvija|
The invention relates to medicine, namely to pathomorphology, and it is associated with post-mortem pathomorphologic brain examination in cases of encephalopathy. The aim of the invention is to develop brain tissue post-mortem detection techniques for pathomorphologic brain examination in cases of encephalopathy, which would allow eliminating discrepancies and errors in post-mortem diagnosis of the disease. The goal is achieved by ensuring that during the pathomorphologic examination of post-mortem brain, it is removed from the skull, and the examination determines skull vault's largest span along the mid-line of the skull's inner surface CD, determines skull vault's largest span along the mid-line of the skull's outer surface GH, cuts a straight front-parietal line (starting from the frontal lobe) of the underside of the two hemispheres, exposing the brain's lateral and third ventricle, then placing it in the preparation bath, fixating both sides of the hemispheres and determining the outer distance between the brain's frontal horns AB, the distance along the midline EF of the lateral ventricle, and the ratio of the coefficient, thus determining post-mortem signs of encephalopathy.
WO/2015/093921 ELECTRIC-MACHINE VOLTAGE CONVERTER||WO||25.06.2015|
||PCT/LV2013/000014||VENTSPILS AUGSTSKOLA||BEZRUKOVS, Valerijs|
The invention relates to electrical equipment for electric trains. A converter consists of a synchronous generator (2) having an armature winding (3) and an excitation winding (4), a drive engine having an armature winding (5) positioned in slots (6) of a rotor (7), and a stationary inductor (8) on which are positioned an independent excitation winding (9) and a consecutive excitation winding (10). A rotor of the generator and a rotor of the drive engine are affixed to the same shaft (11). Outputs of the armature winding (5) are connected to a collector (12) which is located on the shaft of the rotor (7) near one end of the rotor, and are intended for connecting to a direct current voltage source by means of brushes (13). The rotor (7) of the drive engine is provided with a second collector (15) which is positioned on the shaft (11) near the second end of the rotor (7), sections of the winding (5) are made of two identical coils (16, 17) which are oppositely stacked in the slots (6) of the rotor (7) (Fig. 1), and the outputs of each of the coils (16, 17) are connected to a collector (12, 15) located on a corresponding end of the rotor (7). In each section of the winding (5), the coils (16, 17) are connected in series by means of the collectors (12, 15) and the brushes (13), with a shift of 180 electrical degrees. Currents, which pass through the conductors of the coils (16, 17) stacked in each slot (6), move in the same direction.
WO/2015/084134 COMPOSITION OF BIOLOGICALLY ACTIVE SUBSTANCES FOR INHIBITION GRAY ROT BOTRYTIS CINEREA AND PREPARATION METHOD THEREOF||WO||11.06.2015|
||PCT/LV2014/000002||LATVIJAS VALSTS MEŽZINĀTNES INSTITŪTS "SILAVA"||DAUGAVIETIS, Māris|
Invention concerns to forest chemistry branch and covers technology of complete utilization of tree biomass by obtaining biologically active substances with antifungal properties against the fungi Botrytis cinerea. The aim of invention is biologically active products' with antifungal properties against fungi Botrytis cinerea development. The aim is achieved by new product contains spruce bark ethanol extract, ethanol with stabilizer and preservative, sticky agent, emulsifier, potassium hydroxide solution and water.
WO/2015/060702 PHARMACEUTICAL COMPOSITION FOR CONTROLLING BODY MASS GAIN COMPRISING S-PHENOTROPIL||WO||30.04.2015|
||PCT/LV2014/000011||LATVIAN INSTITUTE OF ORGANIC SYNTHESIS||KALVINS, Ivars|
The invention relates to medicine, in particular S-Phenotropil ((S)-2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamide) containing pharmaceutical compositions and their use in control of body mass gain.