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Results 1-10 of 8,516 for Criteria: Office(s):all Language:ES Stemming: true maximize
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TitleCtrPubDate
Int.ClassAppl.NoApplicantInventor
1. WO/2015/044948 COCONUT PALM TREE LEAVES, FAN PALM AND DATE PALM TREE LEAVES FOR HANDMADE AND MILLMADE PAPER MAKINGWO02.04.2015
D21C 1/06
PCT/IN2013/000782VARGHESE, PhilipVARGHESE, Philip
Innovation of coconut palm tree leaves, fan palm and date palm tree leaves for handmade and millmade paper making; Raw materials: available in abundance from nature and very rich in fibre. A permanent solution for shortage of paper raw material worldwide. Pulp: good yield for paper in quality, quantity etc. Paper: suitable for all grades and qualities of paper. Industries: revolutionary industrialization in remote villages of handmade / millmade pulp / paper industries. Income: income, from waste for farmers, traders, employment, industrial growth, environment solution, etc.

2. WO/2015/044949 ELECTRICAL MEMBER FOR ELECTRICAL MACHINESWO02.04.2015
H02K 1/16
PCT/IN2014/000025TVS MOTOR COMPANY LIMITEDNAIR, Sreeju Sreedharan
An electrical member (200) for an electrical machine is described. In an embodiment, the electrical member (200) includes a body portion (208) having a cylindrical shape and a plurality of tapered teeth (210-1) and straight teeth (210-2), both extending in a radial direction from the body portion (208). Each tapered tooth (210-1) and straight tooth (210-2) has its side walls (216-1, 216-2, 218-1, 218-2) extending substantially parallel to a longitudinal axis of the body portion (208) in one direction and extending substantially radially in another direction. Each tapered tooth (210-1) is flanked by a straight tooth (210-2) on either side along a circumferential direction to form a slot (220) between a side wall (216-1) of one tapered tooth (210-1).

3. WO/2015/044950 AN ANTI-LEUKEMIC AGENT USEFUL FOR INDUCING DIFFERENTIATION IN MYELOID LEUKEMIA CELLSWO02.04.2015
A61K 31/4025
PCT/IN2014/000131COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHPAL, Pooja
The present invention provides the compound Ormeloxifene [3, 4-trans-2,2-dimethyl-3-phenyl-4-p- (beta-pyrrolidinoethoxy) phenyl-7-methoxy chroman] as useful in inducing differentiation in wide range of myeloid leukemias including acute promyelocytic leukemia, acute myeloid leukemia and chronic myeloid leukemia where block in differentiation is common feature. Ormeloxifene induced differentiation that is marked by increase in differentiation marker proteins like C/EBPa and surface proteins such as cd11b and granulocyte colony stimulating factor receptor (GCSFr). Differentiated cells having neutrophil like morphology were observed when treated with 1.0 uM to 7.5 uM ORM which clearly indicates that ORM can induce differentiation in myeloid leukemia cells. At higher doses (5uM to 7.5uM) there is early onset of myeloid differentiation ( 24 to 48h ) with reduced no. of cells which is likely due to apoptotic effects of ORM at higher does. In contrary, lower doses (1uM) induce differentiation after longer duration (6-15days) with quite reduced apoptotic effect.

4. WO/2015/044951 3,7-DIAZABICYCLO[3.3.1 ]NONANE CARBOXAMIDES AS ANTITHROMBOTIC AGENTSWO02.04.2015
C07D 471/08
PCT/IN2014/000458COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHDIKSHIT, Dinesh Kumar
The present invention relates to the 3,7-diazabicyclo[3.3.1]nonane carboxamides and process for preparation thereof. The present invention further relates to the compounds of general formula (1) possessing anti-thrombotic (anti-platelet) activities. The invention also relates to use of these moieties as inhibitors of collagen induced platelet adhesion and aggregation mediated through collagen receptors both in vitro and in vivo. Further, invention also relates these class of compounds exhibiting anti-platelet efficacy through dual mechanism inhibited both collagen as well as U46619 (thromboxane receptor agonist) induced platelet aggregation. General formula (1) Wherein, R' is; wherein R is selected from alkyl, acyl, tosyl, tert-butyloxycarbonyl, araalkyl or substituted araalkyl groups; R'' is selected preferably from halogen, cyano, lower alkyl, aryl, substituted aryl, and tosyl groups; R1 is selected from hydrogen and lower alkyl groups; R2 is selected from lower alkyl and aryl groups; R3 is selected from tert-butyloxycarbonyl and bezyloxycarbonyl groups; n = 0,1.

5. WO/2015/044965 A PROCESS FOR PREPARATION OF MIRABEGRON AND ALPHA CRYSTALLINE FORM THEREOFWO02.04.2015
C07D 277/40
PCT/IN2014/000637MEGAFINE PHARMA (P) LTD.MATHAD, Vijayavitthal Thippannachar
An improved process for the preparation of Mirabegron of formula (I) where 4- nitrophenylethylamine of formula (III) or its acid addition salt of formula (IlIa) reacted with compound of formula (XII) in a solvent, optionally in presence of base and/or catalyst to obtain (R)-2-hydroxy-N-[2-(4-nitrophenyl)ethyl]-2-phenylacetamide of formula (XIII) followed by reducing (R)-2-hydroxy-N-[2-(4-nitrophenyl)ethyl]-2-phenylacetamide of formula (XIII) in a solvent to obtain (R)-2-[2'-(4-nitrophenyl)ethyl]amino]-l-phenylethanol of formula (XIV), optionally converting it into its acid addition salt of formula (XlVa); reducing (R)-2-[2'-(4- nitrophenyl)ethyl]amino]-l -phenylethanol of formula (XIV) or its acid addition salt of formula (XlVa) further in solvent to obtain (R)-2-[[2-(4-aminophenyl)ethyl]-amino]-l -phenylethanol of formula (XV) or its acid addition salt of formula (XVa) respectively; and reacting compound (R)- 2-[[2-(4-aminophenyl)ethyl]-amino]-l-phenylethanol of formula (XV) or its acid addition salt of compound of formula (XVa) with compound of formula (VII) in solvent, optionally in the presence of acid, and/or a catalyst to obtain Mirabegron of formula (I) which is further isolated as its a- crystalline form. The compound of formula (XIV) used in the foregoing process can also be prepared by reacting with a compound of formula (III) or acid addition salt of compound of formula (IlIa) in presence of a solvent, a catalyst and optionally in presence of a base to obtain compound of formula (XIV) optionally converting it into its acid addition salt of formula (XlVa); and the same is used in the above-referred process. The compound of formula (XV) used in the foregoing process can also be prepared by reacting a compound of formula (III) or its acid addition salt of formula (IlIa) with a compound of formula (XVI) in a solvent, optionally in presence of a base, optionally in presence of a catalyst to obtain compound of formula (XVII); and optionally isolate the compound of formula (XVII) followed by reducing the compound of formula (XVII) using reducing agent, in a solvent, optionally in presence of a base, optionally in presence of a catalyst to obtain compound of formula (XV) which is further used in the above- referred process for the preparation of Mirabegron of formula (I) and its a-crystalline form. Another additional single-pot process for preparation of Mirabegron of formula (I) is disclosed, wherein compound of formula (XV) or its acid addition salt of formula (XVa) reacted with compound of formula (XVIII) in presence of a solvent and oxidizing agent, optionally in presence of base, optionally in presence of a catalyst to obtain Mirabegron of formula (I).

6. WO/2015/044962 AMORPHOUS FORM OF LEVOMILNACIPRAN HYDROCHLORIDE AND HYDRATES THEREOFWO02.04.2015
C07C 237/30
PCT/IN2014/000632CADILA HEALTHCARE LIMITEDDWIVEDI, Shri Prakash Dhar
The present invention provides an amorphous form of levomilnacipran hydrochloride and process of preparation thereof. The present invention also provides an amorphous solid dispersion comprising levomilnacipran hydrochloride and a polymer.

7. WO/2015/044957 A PROCESS FOR TRANSFORMATION IN WITHANIA SOMNIFERA PLANTS TO INCREASE SECONDARY METABOLITE CONTENTWO02.04.2015
C07K 14/415
PCT/IN2014/000619COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHKHAN, Bashir Mohammad
Described herein is a process of genetic transformation in W. somnifera by Agrobacterium tumefaciens mediated transformation to overexpress squalene synthase gene (WsSQS) encoding WsSQS enzyme that catalyzes the synthesis of squalene from farnesyl pyrophosphate. Increased withanolide level including withaferin-A, withanolide A and B and withanone is attained in transformed plant tissues.

8. WO/2015/044954 EMERGENCY MODE IN A HYBRID VEHICLEWO02.04.2015
B60K 6/20
PCT/IN2014/000606TVS MOTOR COMPANY LIMITEDMAZUMDAR, Dipanjan
The present subject matter relates to a hybrid vehicle having an emergency mode in the form of a limp home mechanism. The limp home mechanism comprises of a manually operated kick start lever connected with the engine, an alternator mechanically connected to the kick start lever, the alternator having a stator and a rotor, and an RR unit taking input from the alternator. The limp home mechanism removes the engine cranking dependency on the controller and the battery and enables manual cranking of the engine in emergency situations.

9. WO/2015/044958 QUANTITATION OF STRUCTURAL ISOMERS USING MALDI MS/MSWO02.04.2015
G01N 33/68
PCT/IN2014/000620COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHPANCHAGNULA, Venkateswarlu
The present invention relates to a quantitative determination of structural isomers implicated in diseases, the said process is completely independent of chromatographic separation, internal standard, and labeled isotopic references. Further, the present invention provides a diagnostic kit for quantitative determination of structural isomers.

10. WO/2015/044964 MAGNETIC NANOPARTICLES DECORATED ACTIVATED CARBON NANOCOMPOSITES FOR PURIFICATION OF WATERWO02.04.2015
B01J 20/20
PCT/IN2014/000636COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCHSAINI, Parveen
The present invention relates to the development of water purifying compositions based on magnetic nanoparticles decorated activated carbon nanocomposites which display both magnetic character as well as adsorbent characteristics. The addition of adsorbent to impure water containing dye as pollutant enables the fast adsorption of dye leading to discoloration of water whereas magnetic properties facilitates the rapid isolation of pollutant adsorbed nanocomposites powder from the purified water with the aid of a magnet. The present invention also provides a process for the development of such multifunctional adsorbent using a process which enables decoration of adsorbent with 5-50 weight % of magnetic nanoparticles, the enables the realization of magnetic adsorbent having saturation magnetization in the range 0.09 to 28.3 emu/g, dye removal efficiency of >99%, rapid decolourization of methylene blue (MB)/methyl orange (MO) dye polluted water in less than 1 min, magnetic separation time in the range <0.2 to 60 min and dye sorption capacity in the range of 3.3x10-4 to 116.3x10-4 mol of MB and 3.6x10-4 to 148.6x10-4 mol of MO dye per 100 gram of nanocomposite powder in a rapid adsorption (<1 min) and magnetic separation process. Besides, these nanocomposites could also be useful for other of applications e.g. as separation of catalytic residues from the products, for removal of oil from water, filler for development of thermally/electrically conducting magneto-rheological fluids or for handling of electromagnetic pollution.


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