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Results 1-10 of 1,030 for Criteria: Office(s):all Language:EN Stemming: true maximize
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TitleCtrPubDate
Int.ClassAppl.NoApplicantInventor
1. WO/2016/020710 METHOD OF DETERMINING PIK3CA MUTATIONAL STATUS IN A SAMPLEWO11.02.2016
C12Q 1/68
PCT/GR2015/000036PHARMASSIST LTD LIANIDOU, Evrykleia
The invention relates to an ultra-sensitive and highly specific methodology for the detection of PIK3CA mutations in the biological samples of cancer patients that is based on a combination of allele-specific, asymmetric rapid PCR and melting analysis in a DNA sample from Circulating Tumor Cells (CTCs), cell-free DNA (cfDNA) in plasma/serum, or Formalin-Fixed Paraffin-Embedded tissues (FFPE). Using the allele-specific primers for each hotspot mutations in exons 9 and 20 (E545K and H1047R, respectively), according to the invention detection can enhance the amplification of the mutant PIK3CA allele sequence, whereas the presence of the corresponding competitive blocking unlabeled probes for each exon can avoid the non-specific amplification of the wild-type PIK3CA sequence increasing the sensitivity and the specificity of method. The mutational detection is completed with the melting curve analysis of the unlabeled probe and the DNA template of the mutant PIK3CA sequence. The evaluation of PIK3CA mutational status on CTC in peripheral blood and cfDNA in plasma/serum of cancer patients is a strategy with potential clinical applications and could have an important impact on therapeutic interventions since the presence of PIK3CA mutations is associated with response to molecular targeted therapies.

2. WO/2016/016669 MULTI STAGE VAPOR COMPRESSION FOR HIGH EFFICIENCY POWER PRODUCTION AND HEAT PUMPWO04.02.2016
F25B 25/02
PCT/GR2015/000038STYLIARAS, Vasilelos STYLIARAS, Vasilelos
The method combines different electrolyte solutions having the same solvent. The solution is successively compressed and vaporized at different temperatures and the vapor is successively absorbed by the second solution that exhibits higher negative deviation, at higher temperature. The absorption heat of each absorber is recovered by the next evaporator. The more evaporator - absorber pairs that are used the higher the temperature lift or the created pressure ratio. Finally the vapor returns to the first solution at high temperature. Electrolyte is dissolved and rejected from each solution to achieve total heat recovering and the very high efficiency of the cycle. Gas absorption is suggested instead of solvent vapor.

3. WO/2016/016670 ABLATING SIC WAFER CONFIGURATIONS AND MANUFACTURING LIGHT EMITTING DIODE (LED) DEVICESWO04.02.2016
H01L 33/20
PCT/GR2015/000040FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS INSTITUTE OF ELECTRONIC STRUCTURE AND LASERS STRATAKIS, Emmanouil
The invention proposes a manufacturing method for enhancement of the luminosity of SiC-based LED devices using double exposure of the light-emitting surface of a LED device or LED component or SiC wafer to linearly polarized radiation of a femtosecond laser beam of a proper fluence. The first exposure results in the formation of a pattern of parallel periodic grooves onto SiC surface. Then the LED device, or LED component, or SiC wafer is rotated by 90 degrees and subsequently irradiated for a second time. The double exposure results in the formation of an array of regular depressions and nanogrooves onto SiC surface. These depressions act as an anti- reflecting coating due to smooth variation of the refractive index from its value in the crystal to air and lead to the increase of internal quantum efficiency of LED. The manufacturing method can be performed during the LED device fabrication or as a pre- or post- fabrication step. The manufacturing process can be performed in air or after immersion of a LED device, or LED component, or SiC wafer in liquid.

4. WO/2016/009233 ROTATIONAL MECHANICAL POWER GENERATING SYSTEMWO21.01.2016
F03G 3/00
PCT/GR2014/000039KARRAMANOUKIAN, Haroutoun KARRAMANOUKIAN, Haroutoun
A machine mechanically controlled to generate power by using the gravity force consisting of main arms (6), secondary arms (9) and tertiary arms (16) with accessories, characterized in that the arms move simultaneously in opening and closing manner through articulated joints and bearings, the machine rotating as a whole, where a lower articulated bar (28) assisting movement of the secondary arm (9) in high position, moving by the ball bearing (27), when the secondary arm (9) rests thereon, causes the articulated bar (28) to carry on its stroke with the secondary arm (9) in the amount of 20% of the stroke remaining for the secondary arm, with the main arm (6) and accessories.

5. WO/2016/005776 MULTI-USE BEEHIVEWO14.01.2016
A01K 47/00
PCT/GR2015/000033GEROGIANNIS, Aristos GEROGIANNIS, Aristos
The invention relates to a multi-use beehive, which consists of a base (1), a deck (2), an inner supplier (3), a queen partition (22) and a lid (4). The base (1) has spacers (7), flying boards (8) for the bees and a perforated floor (12). The deck (2) consists of two parts (14), (15) with an inner insulation (18) and a connection flange (5). The inner supplier (3) has a pan (25) and grid (26) for receiving liquid and solid feed respectively, while the queen partition (22) allows accommodation of the queen. Finally, the lid (4) has also an insulation (18) and aeration ports (6). The beehive is made of plastic and its parts comprise holes for the assemblying thereof by means of pins (19).

6. WO/2015/198080 USING HIGH FREQUENCY VIBRATION FOR OPERATIONAL IMPROVEMENT OF MEMBRANE FILTRATION PROCESSWO30.12.2015
B01D 63/16
PCT/GR2015/000032CHATZIKONSTANTINOU, Konstantinos CHATZIKONSTANTINOU, Konstantinos
The present invention provides method and system for controlling membrane fouling in a membrane filtration process which is well tested in a pilot MBR system treating synthetic wastewater (SWW) as a municipal simulated wastewater, using small copies of commercialized modules and different type of membranes working for a long period, wherein said fouling control includes high frequency membrane vibration. The mechanical energy of vibrated apparatus is used to create and/or increase the shear-rate at the interface of the membrane filtration element in order to increase or improve rejection of the remaining or stacked elements, thus reducing or eliminating the accumulation of these retentate compounds, which causes blockage of the membranes. The method and system according to the present invention, works in situ at the relaxing intervals of the filtration process in a continuous or intermittent mode. The results of the present invention in accordance with the attached diagrams proven that there is no need of continuous use of HFPV process, as if a periodic vibration applied. The main goal of this invention was to establish a method/system to prevent or to remove deposits from filtration membranes used in a fluid separation process, by means of vibrators coupled either directly to the membranes or to the frame bearing said membranes, wherein the vibration applied in periods of membranes relaxing, which alternate with periods of active filtration, without vibration. Vibration can take place mainly in a direction parallel or perpendicular to the surface of the membranes themselves or the surface of the array of membrane elements, at amplitude ranging from 0.1-1.5 mm, but also in other directions, at smaller amplitude. Preferably vibrator's frequency ranges from 20 to 600 Hz, wherein the frequency, amplitude and/or waveform of the vibration can be constant or may be varied, during the membrane cleaning process and can be properly regulated according to the system needs, with an advanced monitoring operational system. It is a further object of this invention to provide an MBR system that does not utilize membrane air scouring as main cleaning process but as an associated cleaning system and process thus reducing energy consumption. In addition one more issue of this invention is to provide a new approach for the membranes' cleaning, taking into consideration for the first time the cleaning water temperature in a tank or in backwash process with or without vibration.

7. WO/2015/193692 DEVICE FOR DELIVERING AN INSULATION ENHANCING POLYURETHANE FOAM WITHIN PROFILES USED IN DOORS, WINDOWS AND RELATED APPLICATIONSWO23.12.2015
B29C 44/38
PCT/GR2015/000031TZIKA, Asimo TZIKA, Asimo
A device adapted to deliver an insulation enhancing polyurethane foam within profiles used in doors, windows and related applications comprising an insulating material supply member (1) extending into a polyurethane forming and discharge member (2) adapted to enter and move linearly along a chamber (25, 35) of a thermally insulated sash or frame profile assembly and deliver therein a polyurethane foam that absolutely abuts onto the walls of the chamber without exerting undesirable stresses thereupon. The insulating material supply member (1) comprises independent pipes (8, 9) delivering a polyol constituent (A) and an isocyanate constituent (B) that are mixed together with a supply of air within a mixing compartment (4) of the polyurethane forming and discharge member (2) to produce the desired insulating material. The polyurethane supplying assembly starts injection at one end of the profile bar having an industrial standard length and moves reawards to fill the chamber with the polyurethane insulating material.

8. WO/2015/189647 MOLDS FOR CUSTOM DENTAL IMPLANT ABUTMENTS AND IMPRESSION POSTSWO17.12.2015
A61C 13/00
PCT/GR2015/000029VERGOULLIS, loannis VERGOULLIS, loannis
Molds for fabrication of custom and potentially modifiable abutments and impression posts for dental implants with various degrees of angulations (including zero degrees) and various dimensions are provided, with a generally oval shape that expands laterally upwards, a symmetrical or asymmetrical cross-section, and regular surfaces, that are fabricated as one piece, or as two coupling pieces snapping onto each other. Custom abutments achieve the development of a custom gingival emergence profile, three dimensionally, which is potentially modifiable according to the needs of each particular clinical case. Custom impression posts that correspond in dimensions and angulations to the abutments allow the accurate recording and transfer of the developed gingival emergence profile from the mouth onto the working cast, where the final implant prosthesis is fabricated. The custom abutments and impression posts have properties and design that allows their preparation and usage as temporary abutments for the cementation and support of temporary prostheses, following the same principals as per teeth temporary rehabilitation, but they can also be scanned by a digital scanner for the generation of a digital impression and the fabrication of a digital prosthesis.

9. WO/2015/189648 ABUTMENTS AND IMPRESSION POSTS FOR DENTAL IMPLANT PROCEDURESWO17.12.2015
A61C 8/00
PCT/GR2015/000030VERGOULLIS, Ioannis VERGOULLIS, Ioannis
The fabrication of straight and angulated, custom, potentially modifiable abutments; straight, custom, potentially modifiable open tray impression posts; and straight and angulated, custom, potentially modifiable closed tray impression posts is provided. The custom abutments achieve the development of a three dimensionally customized gingival emergence profile according to the needs of each clinical case in different sizes and dimensions around the implant platform. Impression posts corresponding to the custom abutments in dimensions and angulations allow the recording and transfer of the developed gingival profile from the mouth onto the working cast in order for the final prosthesis to be fabricated accurately, while they also have independent parts that improve the quality of the results of the implant treatment process. The custom abutments and impression posts moreover can be modified to be temporary abutments used to support a temporary prosthesis and can also be scanned by a digital scanner in order to generate a digital impression and or digital working cast.

10. WO/2015/185950 TRANSPORTABLE FOLDABLE APPARATUS FOR THE ACCESS OF PEOPLE WITH MOBILITY PROBLEMS TO THE SEAWO10.12.2015
E01C 9/08
PCT/GR2015/000028MANTELAKIS, Antonios MANTELAKIS, Antonios
The present invention is a folding transportable apparatus for the access of people with mobility problems to the sea, consisting of a folding moving walkway (1), a people-carrying wheelchair (4) which moves freely on said walkway, a drive mechanism (2) for assisting with the moving of the wheelchair and a transport wheel base (3). It is a compact technical solution, with few peripheral parts, for transport to and from the beach / sea, a non-permanent structure, with little construction time, stable on sandy ground and with low construction costs, while the transport wheel base ensures ergonomic storage and transport of the entire folding apparatus.


Results 1-10 of 1,030 for Criteria: Office(s):all Language:EN Stemming: true
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