WO/2016/112878 ELECTRONIC GERMICIDAL DEVICE||WO||21.07.2016|
||PCT/CZ2015/000002||ČERMÁK, Mojmír||ČERMÁK, Mojmír|
In the electronic germicidal device comprising a source of pulsed voltage and a pair of electrodes to be applied on the treated tissue the electrodes (8, 9) placed on a plastic film form at least partially a system of parallel or concentric lines with opposite polarity of the neighbouring electrodes (8, 9).
WO/2016/112882 MACROMOLECULAR CONJUGATES FOR ISOLATION, IMMOBILIZATION AND VISUALIZATION OF PROTEINS||WO||21.07.2016|
||PCT/CZ2016/050002||USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I.||SACHA, Pavel|
The invention provides a synthetic macromolecular conjugate for selective interaction with proteins, comprising a synthetic copolymer, and at least one binding group and at least one further group selected from an affinity tag and an imaging probe, said at least one binding group and at least one further group being bound via covalent bond to said synthetic copolymer. The macromolecular conjugate is suitable in particular for identification, visualization, quantification or isolation of proteins and/or cells.
WO/2016/112879 CRYSTALLINE MODIFICATION 2 OF (3/R)-3-AMINO-1-[3-(TRIFLUOROMETHYL)-6,8-DIHYDRO-5H-[1,2,4]TRIAZOLO[4,3-α]PYRAZIN-7-YL]-4-(2,4,5-TRIFLUOROPHENYL)BUTAN-1-ONE L-TARTRATE||WO||21.07.2016|
||PCT/CZ2016/000001||ZENTIVA, K.S.||RICHTER, Jindrich|
Crystalline Modification 2 of Sitagliptin L-tartrate salt, exhibiting the following characteristic diffraction peaks: 5.83; 15.63; 17.73; 25.58; 26.44 ± 0.2° 2-theta. (Formula)
WO/2016/112883 MACROMOLECULAR CONJUGATES FOR VISUALIZATION AND SEPARATION OF PROTEINS AND CELLS||WO||21.07.2016|
||PCT/CZ2016/050003||USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I.||SACHA, Pavel|
The present invention describes macromolecular water-soluble conjugates based on synthetic copolymers to which at least one affinity tag, at least one imaging probe and at least one targeting ligand are bound via covalent bonds. The macromolecular conjugate may be used in identification, visualization, quantification or isolation of proteins and/or cells.
WO/2016/112880 CRYSTALLINE MODIFICATION 3 OF (3R)-3-AMINO-L-[3-(TRIFLUOROMETHYL)-6,8-DIHYDRO-5H- [L1,2,4]TRIAZOLOL[4,3-]PYRAZIN-7-YL]-4-(2,4,5-TRIFLUOROPHENYL)BUTAN-1-ONE L-TARTRATE||WO||21.07.2016|
||PCT/CZ2016/000002||ZENTIVA, K.S||RICHTER, Jindrich|
Crystalline Modification 3 of Sitagliptin L-tartrate salt, exhibiting following characteristic diffraction peaks: 4.22; 15.87; 16.58; 20.8; 22.72 ± 0.2° 2-theta. (Formula)
WO/2016/112881 DUAL MICROBIAL PREPARATION FOR LONG-TERM SUPPRESSION OR PREVENTION OF SYMPTOMS OF OPPORTUNISTIC MICROBIAL INFECTIONS||WO||21.07.2016|
||PCT/CZ2016/000007||BIO AGENS RESEARCH AND DEVELOPMENT - BARD s.r.o.||SUCHÁNEK, Martin|
The dual microbial preparation contains the microscopic oomycete Pythium oligandrum and components of a physiological microbiome. The microscopic oomycete Pythium oligandrum and the physiological microbiome component are present in the dual preparation in a form which facilitates their germination, subsequent propagation and colonization of the target tissues. The microscopic oomycete Pythium oligandrum is incorporated in a quantity of 103 to 107 CFU (colony forming units), with 104 to 105 CFU per one cycle of application preferably. The physiological microbiome component contains 5x 106 to 5x1010 CFU, with 5x107 to 5x109 per one cycle of application preferably. The fermented substrate found in the Pythium oligandrum oomycete is the source of nutrients for both microbial components. The dual microbial preparation also contains at least one auxiliary substance from a group including a desiccant, components of a buffer system, an anti-caking substance and an agent for the creation of a physiological osmotic environment. The physiological microbiome component is a component of the human microbiome, one of the microbes of the green complex, such as the Capnocytophaga sputigena bacterium, or one of the components of the healthy skin microbiome, such as the Staphyloccocus epidermidis bacterium, or one of the components of the healthy vaginal microbiome, such as the peroxide producing Lactobacillus crispatus. Either the microscopic oomycete Pythium oligandrum or the physiological microbiome component is present in the dual microbial preparation in the form of inactivated cells, cell extracts or isolated cell fractionation. The microbial activator for the Pythium oligandrum oomycete is a yeast autolysate in a quantity of 0.1 % to 10 % weight of the total quantity of dual microbial preparation. The auxiliary substances are regulated in a way which allows for application in the form of an ointment, cream, oil or suppository or in the form of a liquid aqueous preparation.
WO/2016/107617 FILTER FOR REMOVAL OF INORGANIC AND ORGANIC SUBSTANCES FROM CONTAMINATED WATER||WO||07.07.2016|
||PCT/CZ2015/000050||VYSOKÁ ŠKOLA BÁŇSKÁ - TECHNICKÁ UNIVERSITA OSTRAVA||PLACHÁ, Daniela|
A filter for removal of inorganic and organic substances from contaminated water consisting of a casing provided with a lower bottom and a removable lid and further comprising water inlet and water outlet inside which a patron with adsorbent material based on modified clay minerals is arranged, characterized in that the adsorbent material is arranged in layers, which comprise at least one layer of modified clay mineral with organic cations with different chain lengths and at least one layer based on natural clay mineral or clay mineral in sodium form.
WO/2016/101939 ENTHALPY HEAT EXCHANGER||WO||30.06.2016|
||PCT/CZ2015/000153||RECUTECH S.R.O.||CHLUP, Jaroslav|
The invention relates to a counter flow enthalpy exchanger (1) having a parallelogram-shaped central part (11), whose ends in the flow direction through the exchanger it is joined by end parts (12, 13), which become narrower in the direction from the central part (11), whereby in order to separate the flow of the heat-transfer medium in the direction from the inner space to the outer space are arranged contour identical and with respect to the flowing medium sealed vapour-permeable lamellae (10) with shaping means for generating turbulent flow, whereby every two adjacent lamellae (10) form one interplate flow channel in the central part (11) one interplate flow channel. The lamella (10) is made as a one-piece self-supporting moulding common to the central part (11) and the end parts (12, 13), whereby it does not have a reinforcing support grid. Two adjacent lamellae (10) form one interplate flow channel in the end part (12, 13), in the walls of which are formed straight protrusions (121, 131) situated in the direction of the heat-transfer medium flow between the central part (11) and corresponding inlet or outlet of this medium.
WO/2016/101938 METHOD FOR PRODUCING SECONDARY POLYOLS AND THEIR USE||WO||30.06.2016|
||PCT/CZ2015/000152||VYSOKÉ UČENI TECHNICKÉ V BRNĚ||PETRŮJ, Jaroslav|
The method for producing secondary polyols by means of recycling secondary raw materials containing waste PIR foams, lies in mixing ground waste polyisocyanurate (PIR) foams with polyester based polymers and subjected to controlled glycerolysis in microwave field where it undergoes mixed catalytic depolymerization and secondary polyol is formed in the form of homogeneous liquid product. Mixed catalytic depolymerization is carried out in two phases and with alkali metal carboxylate based catalyzer having the chainlength C6-C20, preferably C6-C12, and/or with organic guanidine and amidine superbases and their mixtures present in glycerol, at concentrations 0,1 up to 1,0 mol.l-1. In the first phase polyester is depolymerized in alcoholysis agent - glycerol and in the second phase PIR foams are depolymerized in the mix of residual agent and oligoesters and polyols formed in the first stage. The reaction mixture subjected to mixed catalytic depolymerization contains 15 to 30 wt. % of waste PIR foams having the isocyanurate index higher than 2, 20 to 40 wt. % of polyesters, preferably waste polyethyleneterephtalat.es, and 40 to 60 wt. % of glycerol. Secondary polyols can be used to prepare new polyisocyanurate foams in the mixture of virgin (primary) and recycled (secondary) polyol. The content of secondary polyol in the mixture of virgin (primary) and recycled (secondary) polyol ranges within 5 - 25 wt. %.
WO/2016/101937 MODEM FOR DATA TRANSMISSION OVER HIGH VOLTAGE DISTRIBUTION LINES||WO||30.06.2016|
||PCT/CZ2015/000138||MODEMTEC s.r.o.||KACALA, Vladislav|
Modem for data transmission over high voltage distribution lines comprises a block (JADRO) that contains at least two serial communication ports (UART) and at least two ports (I/O) accessible via a connector (PK). The block (JADRO) further comprises a gate array (FPGA), an input analog-digital converter (AD) and an output digital-analog converter (DA). To the gate array (FFGA) a circuit (CPLD) is connected for booting firmware in the memory (RAM) to ensure the required function of the gate array (FPGA) after turning on of the power supply. The circuit (CPLD) is designed to ensure data protection and to check data handling for correctness. The memory (RAM) is connected to the gate array (FPGA) to ensure the entire operation of the gate array (FPGA) program. A memory (FLASH) is also connected to the gate array (FPGA) for saving of internal data. The gate array (FPGA) is equipped with an internal processor (ALU) and has such an internal hardware structure to be able to use the processor (ALU) for the control of processing, reception and transmission of data.