Colecciones nacionales e internacionales de patentes

1. (WO2018064499) PEPTIDE INHIBITORS OF SODIUM CHANNELS

Pub. No.:    WO/2018/064499    International Application No.:    PCT/US2017/054339
Publication Date: Fri Apr 06 01:59:59 CEST 2018 International Filing Date: Sat Sep 30 01:59:59 CEST 2017
IPC: A61K 38/00
A61K 38/08
A61K 38/17
C07K 7/00
C07K 14/435
Applicants: SPYRYX BIOSCIENCES, INC.
Inventors: CROWDER, Timothy, Morgan
CHRISTENSEN, Dale, J.
TAYLOR, John, Clayton
Title: PEPTIDE INHIBITORS OF SODIUM CHANNELS
Abstract:
The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of specialized non-naturally occurring peptides to sodium channels.