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Analysis

1 / 7,150
1.000019827387Use of ligands of the high affinity binding site of diisopropyl-fluorophosphate in treatment of central nervous system disorders
DE - 23.12.1999
Int.Class A61K 31/66
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
66Phosphorus compounds
 Appl.No 19827387 Applicant BAYER AG Inventor SCHMIDT BERNARD

The use of ligands of the high affinity binding site of diisopropyl-fluorophosphate (DFP) at mammalian brain membranes in the preparation of medicaments for prevention and treatment of central nervous system disorders, is new.

2.000003811274Neue Anwendungen von Dopamin Rezeptor-Agonisten
DE - 27.10.1988
Int.Class A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
 Appl.No 3811274 Applicant SANDOZ AG Inventor MARKSTEIN RUDOLF DR
3.0000698120104-Aminopyrrole (3,2-d) Pyrimidinen als Antagonisten des Neuropeptide Y Receptors
DE - 26.02.2004
Int.Class A61K 31/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
 Appl.No 69812010 Applicant PFIZER PRODUCTS INC., GROTON Inventor DOW, ROBERT LEE
4.WO/1999/067229NEW 2-AMINOCARBONYL-5(2H)-ISOXAZOLONES AS LIGANDS OF A DFP-BINDING SITE FOR TREATMENT OF CNS-DISEASES
WO - 29.12.1999
Int.Class C07D 261/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
261Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
02not condensed with other rings
06having two or more double bonds between ring members or between ring members and non-ring members
10with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
12Oxygen atoms
 Appl.No PCT/EP1999/004030 Applicant BAYER AKTIENGESELLSCHAFT Inventor LENSKY, Stephan
The invention relates to new 2-aminocarbonyl-5(2H)-isoxazolones used as selective ligands of a high-affinity binding site of diisopropyl-fluorophosphate (DFP) on brain membranes, for prophylaxis and treatment of diseases of the central nervous system, especially cognitive disorders, depression, schizophrenia and anxiety.
5.000060111621DECAHYDRO-ISOCHINOLINDERIVATE
DE - 18.05.2006
Int.Class C07D 401/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
06linked by a carbon chain containing only aliphatic carbon atoms
 Appl.No 60111621 Applicant NOVARTIS AG Inventor TROXLER J
6.0000698304094-AMINOPYRROLE[3,2-D]PYRIMIDINE ALS NEUROPEPTID REZEPTOR ANTAGONISTEN
DE - 26.01.2006
Int.Class C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
 Appl.No 69830409 Applicant PFIZER PROD INC Inventor DOW LEE
7.000060218032NEUER, FÜR DIE THERAPIE GEEIGNETER LIGAND FÜR NIKOTINISCHE ACETYLCHOLINREZEPTOREN
DE - 16.08.2007
Int.Class C07D 491/22
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
491Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
22in which the condensed system contains four or more hetero rings
 Appl.No 60218032 Applicant ASTRAZENECA AB Inventor PHILLIPS EIFION
8.000069617712INDOLDERIVATE ALS MELATONINANALOGE
DE - 06.05.2004
Int.Class C07D 209/34
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02condensed with one carbocyclic ring
04Indoles; Hydrogenated indoles
30with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
32Oxygen atoms
34in position 2
 Appl.No 69617712 Applicant BESINS INTERNATIONAL PARIS LAB Inventor FOURTILLAN JEAN-BERNARD
9.000069612852BENZO[g]CHINOLINDERIVATE
DE - 04.10.2001
Int.Class C07D 221/08
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
221Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/-C07D219/187
02condensed with carbocyclic rings or ring systems
04Ortho- or peri-condensed ring systems
06Ring systems of three rings
08Aza-anthracenes
 Appl.No 69612852 Applicant NOVARTIS AG Inventor NEUMANN, PETER
10.000060204044PIPERAZIN DERIVATE MIT SST1 ANTAGONISTISCHER WIRKUNG
DE - 19.01.2006
Int.Class C07D 311/9
Appl.No 60204044 Applicant NOVARTIS AG Inventor TROXLER J
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