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Analysis

1.104587180Traditional Chinese medicine composition for alleviating gastrointestinal adverse reaction caused by AIDS (Acquired Immune Deficiency Syndrome) antiviral drug
CN 06.05.2015
Int.Class A61K 36/8968
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
8968Ophiopogon (Lilyturf)
Appl.No 201510056343.4 Applicant DENG XIN Inventor DENG XIN
The invention discloses a traditional Chinese medicine composition for alleviating gastrointestinal adverse reaction caused by AIDS antiviral drug. The traditional Chinese medicine composition is characterized by being prepared from the following traditional Chinese medicine raw materials in parts by weight: 20-30 parts of poria, 15-25 parts of hawthorn, 8-12 parts of tangerine peel, 6-10 parts of Atractylodes, 15-25 parts of radix bupleuri, 8-12 parts of astragalus root, 14-18 parts of fructus aurantii, 6-10 parts of radix paeoniae alba and 4 to 8 parts of radix ophiopogonis. The medicine composition provided by the invention, with consideration of factors in Guangxi, such as climatic characteristics, physical characteristics, environmental factors and dietary habits, can effectively alleviate gastrointestinal adverse reaction caused by AIDS antiviral drug, enhance appetite of patients, improve CD4 cell population and boost immunity.
2.110841069Pharmaceutical composition comprising thalidomide and antifungal agent and application thereof
CN 28.02.2020
Int.Class A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Appl.No 201911314649.X Applicant FIRST AFFILIATED HOSPITAL OF KUNMING MEDICAL UNIVERSITY Inventor LI YUYE
The invention discloses a pharmaceutical composition comprising thalidomide and an antifungal agent and application thereof; the pharmaceutical composition comprises thalidomide and an antifungal agent and is used for preparing drugs for the treatment of acquired immune deficiency syndrome complicated by Penicilliosis marneffei's disease. The pharmaceutical composition has a stronger therapeutic effect on mice infected with acquired immune deficiency syndrome complicated by Penicilliosis marneffei's disease than an antifungal agent alone, and is also stronger than thalidomide alone. Accordingto the invention, the treatment dosage of the antifungal agent is reduced, the effect of inhibiting Penicillium marneffei is enhanced, and the treatment effect is effectively improved.
3.103520426Traditional Chinese medicine for relieving gastrointestinal side effects caused by acquired immune deficiency syndrome antiviral drug
CN 22.01.2014
Int.Class A61K 36/8945
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
894Dioscoreaceae (Yam family)
8945Dioscorea, e.g. yam, Chinese yam or water yam
Appl.No 201310494391.2 Applicant Deng Xin Inventor Deng Xin
The invention discloses a traditional Chinese medicine for relieving gastrointestinal side effects caused by acquired immune deficiency syndrome antiviral drug. The traditional Chinese medicine is characterized by comprising the following active ingredients in parts by weight: 10-30 parts of radix codonopsis, 10-25 parts of rhizoma atractylodis macrocephalae, 15-40 parts of poria, 5-15 parts of dried orange peels, 5-20g of rhizoma pinellinae praeparata, 5-20g of radix aucklandiae, 5-15g of dioscorea roots, and 5-20 parts of fructus crataegi. The medicine can relieve the bad effect caused by anti-virus medicine on a digestive tract, promote the appetite of a patient, increase the number of CD4 cells, and enhance the immunity.
4.104666992Traditional Chinese medicine composition for relieving hepatic and renal function injuries caused by antiviral medicines for AIDS
CN 03.06.2015
Int.Class A61K 36/899
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
Appl.No 201510056350.4 Applicant 邓鑫 Inventor 邓鑫
The invention discloses a traditional Chinese medicine composition for relieving hepatic and renal function injuries caused by antiviral medicines for AIDS. The traditional Chinese medicine composition is characterized by being prepared from the following raw materials in parts by weight: 15-25 parts of paeonia suffruticosa, 8-12 parts of Chinese yam, 20-30 parts of poria cocos, 6-10 parts of rhizoma atractylodis macrocephalae 15-25 parts of gentian, 8-12 parts of astragalus membranaceus, 14-18 parts of angelica sinensis, 6-10 parts of white paeony root and 4-8 parts of corn stigma. The traditional Chinese medicine product is applied to treatment of the diseases such as liver blood deficiency, hypotension, incomplete cerebral blood supply and angina, is capable of effectively relieving the hepatic and renal function injuries caused by the antiviral medicines of AIDS, and has the advantages of high treatment speed, high curative effect and low treatment cost.
5.111617161Traditional Chinese medicine composition for relieving liver and kidney injury caused by AIDS antiviral drugs
CN 04.09.2020
Int.Class A61K 36/815
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
815Lycium (desert-thorn)
Appl.No 202010451273.3 Applicant YUNNAN INSTITUTE OF TRADITIONAL CHINESE MEDICINE Inventor CAI YI
The invention provides a traditional Chinese medicine composition for relieving liver and kidney injury caused by AIDS antiviral drugs, and relates to the technical field of traditional Chinese medicine treatment. The traditional Chinese medicine composition for relieving the liver and kidney injury caused by the AIDS antiviral drugs comprises the following traditional Chinese medicines: radix angelicae sinensis, Chinese wolfberry, radix astragali, radix paeoniae alba, radix ginseng, colla corii asini, radix rehmanniae preparata, radix glycyrrhizae, cortex eucommiae, fructus psoraleae, cortexmoutan, rhizoma atractylodis macrocephalae and the like. The immunity of a human body is improved through the radix angelicae sinensis, the Chinese wolfberry, the radix astragali and the radix ginseng; qi deficiency and blood deficiency of a patient are improved through the radix paeoniae alba, the colla corii asini, the radix rehmanniae preparata and the radix glycyrrhizae; the injured liver andkidney of the human body are nourished and the injury is improved through the cortex eucommiae, the fructus psoraleae, the cortex moutan and the rhizoma atractylodis macrocephalae; design is reasonable; qi-blood deficiency of the patient is improved; the immunity of the patient is enhanced; subsequent treatment can be smoother; and meanwhile, traditional Chinese medicine ingredients for nourishingthe liver and the kidney can be better absorbed.
6.102575256Genetically modified sequences encoding plasmodium vivax antigens
CN 11.07.2012
Int.Class C12N 15/30
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
30Genes encoding protozoal proteins, e.g. from Plasmodium, Trypanosoma, Eimeria
Appl.No 200980160391.0 Applicant Universidade Federal De Minas Gerais-Ufmg Inventor Bruna Romero Oscar
The present invention relates to the construction of modified genetic sequences, which comprise sequences for antigens (DBP-PA, DBP-AM, DBP-MT, AMA-1, CS and MSP-1 ) of Plasmodium vivax, the corresponding recombinant proteins encoded by said sequences as well as genetically modified viruses that express these recombinant antigens. In addition, the present invention refers to a method of prime-boost vaccination using adenoviral or poxviral vectors, purified proteins for immunization of mammals and vaccine compositions to be used as vaccines against malaria.
7.1927259Antifungal pharmaceutical composition for preventing patient fungus infection
CN 14.03.2007
Int.Class A61K 36/489
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
489Sophora, e.g. necklacepod or mamani
Appl.No 200610062370.3 Applicant Shenzhen Southchina Biotechnoyogy Co., Ltd. Inventor Guan Biwei
An antifungal agent combination for preventing patients from fungal infection, it is prepared according to common technique using the raw materials in the following weight ratio: 20 shares of honeysuckle, 30 shares of Indian chrysanthemum herb or root, 30 shares of balsampear root, and 20 shares of lightyellow sophora root. The advantages of the present invention is : with long-term use of the invention products, it can prevent and cure AIDS patients with oral fungal infection which is the most common AIDS opportunistic infections and can spread to the throat and esophagus, resulting in glossopharyngeal pain, Hampering foodintake, even spread all over the body, especially the lungs, brain infections. Control of oral fungal infection of AIDS patients is an important part of curing AIDS, and also has actually great significance in improving patient symptoms, enhancing systemic immunity.
8.111398480Kit for simultaneously detecting triazole antifungal drugs and glycopeptide antibiotics and detection method thereof
CN 10.07.2020
Int.Class G01N 30/02
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
30Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
02Column chromatography
Appl.No 202010317906.1 Applicant AUTOBIO DIAGNOSTICS CO., LTD. Inventor CAI KEYA
The invention discloses a kit for simultaneously detecting triazole antifungal drugs and glycopeptide antibiotics, the kit comprises an extracting solution, a diluent, a mobile phase, a calibrator anda quality control material, the calibrator and the quality control material comprise fluconazole, voriconazole, posaconazole, itraconazole, vancomycin and teicoplanin; wherein the extracting solutioncomprises an isotope internal standard substance and a methanol aqueous solution, and the isotope internal standard substance comprises fluconazole-d4, voriconazole-d3, posaconazole-d4 and itraconazole-d5; wherein the diluent is distilled water or ultrapure water. The invention has the advantages that the invention firstly provides a kit capable of detecting a micromolecular antifungal drug and simultaneously detecting macromolecule glycopeptide antibiotics; the kit is simple in sample pretreatment and short in pretreatment time, improves the detection efficiency, can detect multiple types ofmedicines, can meet the detection requirements of clinically high-throughput samples, has a very good application prospect, and is convenient to popularize.
9.WO/2007/093134AIDS VACCINE BASED ON REPLICATIVE VACCINIA VIRUS VECTOR
WO 23.08.2007
Int.Class A61K 39/21
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
21Retroviridae, e.g. equine infectious anemia virus
Appl.No PCT/CN2007/000589 Applicant CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION CENTER FOR AIDS/STD CONTROL AND PREVENTION Inventor SHAO, Yiming
Replicative live-vector vaccine against AIDS expressing antigen of human immunodeficiency virus (HIV) and its application are provided. Said vaccine is constructed on the basis of replicative vaccinia virus, such as vaccinia virus Tian Tan strain. The replicative live-vector vaccine of present invention is capable of inducing high level humoral and cell immunoresponse against HIV. The carrier for constructing said vaccine, and immunization procedure using said vaccine are also provided.
10.101020052AIDS vaccine based on replicative vaccinia virus vector
CN 22.08.2007
Int.Class A61K 39/125
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
125Picornaviridae, e.g. calicivirus
Appl.No 200610007567.7 Applicant VD and AIDS Preventing and Controlling Center, China Disease Preventing and Cont Inventor Shao Yiming
The present invention relates to replicative live AIDS carrier vaccine expressing HIV antigen and its use. The vaccine is constructed based on replicative vaccinia virus, such as vaccinia virus Tiantan strain. The replicative live AIDS carrier vaccine can induce high level HIV resisting body fluid and cellular immune response. The present invention provides the carrier for constructing the AIDS vaccine, and also relates to immunizing process with the AIDS vaccine.